Results 61 to 70 of about 1,249,876 (248)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Who speaks for whom? Can nurses be patient advocates in renal settings? [PDF]

open access: yes, 2014
Nursing texts laud the role of nurses as advocates for patients. With increased acknowledgement of patient-centred care, is it appropriate or desired for nurses to presume this as their role?
Wellard, Sally
core  

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Educación sobre el cáncer en los centros escolares : guía para profesores

open access: yes, 1990
Incluye apéndice con direcciones de interés al respectoTrabajo de educación sanitaria sobre el cáncer y su prevención desde edades tempranas para fomentar una actitud positiva hacia la enfermedad.

core  

Chinese quality control indices for standardized diagnosis and treatment of renal cancer (2022 edition)

open access: yesJournal of the National Cancer Center
Renal cancer is one of the most common malignancies of the urinary system, and the number of deaths continues to increase. The standardized management of the diagnosis and treatment of renal cancer is challenging due to the great differences in the ...
Lin Yao   +18 more
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Evaluación de la citología con balón en el diagnostico precoz del cáncer de esófago.

open access: yes, 1992
El cáncer de esófago es una entidad que en forma anecdótica, ha sido descrita como frecuente en los municipios del Departamento de Cundinamarca (Colombia), ubicados en el antiplano, alrededor de Bogotá.
De Escorcia, Eva Klaus   +2 more
core  

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Editorial

open access: yesRevista Guatemalteca de Urología, 2020
En este volumen tenemos artículos como el de revisión realizado por los doctores Flores–Carbajal y Medrano–Urtecho, quienes logran repasar y actualizar los aspectos más importantes de la Nefrectomía Parcial especialmente en el abordaje Laparoscópico ...
Hugo Roberto Arriaga Morales
doaj  

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

open access: yesMolecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh   +11 more
wiley   +1 more source

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