Results 51 to 60 of about 1,168,282 (300)

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Watershed Colonialism and Popular Geographies of North American Rivers

open access: yesOpen Rivers, 2017
Rivers have long been the subject and vehicle for compelling stories. As physical features that tie natural and human history, rivers in narratives have hidden as much as they’ve revealed by naturalizing cultural practices and human values...
Sigma Colon
doaj   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Long noncoding RNAs: functions and mechanisms in colon cancer

open access: yesMolecular Cancer, 2020
Evidence indicates that long non-coding RNAs (lncRNAs) play a crucial role in the carcinogenesis and progression of a wide variety of human malignancies including colon cancer.
Sian Chen, Xian Shen
semanticscholar   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Influência da peritonite sobre a síntese de colágeno em anastomoses do cólon distal: estudo experimental em ratos

open access: yesActa Cirúrgica Brasileira, 2000
Com o objetivo de verificar a relação entre a concentração de colágeno e a capacidade de suportar pressão em anastomoses de cólon quando existe peritonite, utilizaram-se 40 ratos machos, Wistar-TECPAR, com idade média de 120 dias e peso médio de 302 g ...
Maria de Lourdes Pessole Biondo-Simões   +5 more
doaj   +1 more source

Parthenolide ameliorates colon inflammation through regulating Treg/Th17 balance in a gut microbiota-dependent manner

open access: yesTheranostics, 2020
Inflammatory bowel disease (IBD) is a global health problem in which gut microbiota dysbiosis plays an important pathogenic role. However, the current drugs for IBD treatment are far from optimal. Previous researches indicated that parthenolide (PTL) had
Yao Liu   +12 more
semanticscholar   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Tumores malignos sincrônicos de cólon e reto. [PDF]

open access: yes, 1999
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Departamento de Clínica Cirúrgica, Curso de Medicina, Florianópolis ...
Silva, Marisa Helena da
core  

The relationship of E-cadherin with colorectal adenocarcinoma prognosis [PDF]

open access: yes, 2005
BACKGROUND: To evaluate the relationship between E-cadherin and recurrence, relapse free survival, overall survival and TNM system in patients operated on for colorectal adenocarcinoma.
Artigiani Neto, Ricardo   +3 more
core   +1 more source

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