Results 41 to 50 of about 19,520 (191)

Direct arylation catalysis with chloro[8-(dimesitylboryl)quinoline-κN]copper(I)

Beilstein Journal of Organic Chemistry, 2016
We report direct arylation of arylhalides with unactivated sp2 C–H bonds in benzene and naphthalene using a copper(I) catalyst featuring an ambiphilic ligand, (quinolin-8-yl)dimesitylborane.
Sem Raj Tamang, James D. Hoefelmeyer
doaj   +1 more source

“On Water” Palladium Catalyzed Direct Arylation of 1H-Indazole and 1H-7-Azaindazole

Molecules, 2020
The C3 direct arylation of 1H-indazole and 1H-7-azaindazole has been a significant challenge due to the lack of the reactivity at this position. In this paper, we describe a mild and an efficient synthesis of new series of C3-aryled 1H-indazoles and C3 ...
Khadija Gambouz, Abdelmoula El Abbouchi, Sarah Nassiri, Franck Suzenet, Mostapha Bousmina, Mohamed Akssira, Gérald Guillaumet, Saïd El Kazzouli   +7 more
doaj   +1 more source

Confirming the existence of π-allyl-palladium intermediates during the reaction of meta photocycloadducts with palladium(ii) compounds [PDF]

, 2000
The transient existence of π-allyl-palladium intermediates formed by the reaction of Pd(OAc)2 and anisole-derived meta photocycloadducts has been demonstrated using NMR techniques.
Penkett, Clive S, Brann, Paul J, Woolford, Jason A, Kahan, Rachel J   +3 more
core   +3 more sources

Recent Developments in C–H Activation for Materials Science in the Center for Selective C–H Activation

Molecules, 2018
Organic electronics is a rapidly growing field driven in large part by the synthesis of π-conjugated molecules and polymers. Traditional aryl cross-coupling reactions such as the Stille and Suzuki have been used extensively in the synthesis of &pi ...
Junxiang Zhang, Lauren J. Kang, Timothy C. Parker, Simon B. Blakey, Christine K. Luscombe, Seth R. Marder   +5 more
doaj   +1 more source

A modular approach to prepare enantioenriched cyclobutanes: synthesis of (+)-rumphellaone A [PDF]

, 2019
A modular synthesis of enantioenriched polyfunctionalized cyclobutanes was developed that features an 8-aminoquinolinamide directed C–H arylation reaction. The C–H arylation products were derivatized through subsequent decarboxylative coupling processes.
Beck, Jordan C., Chapman, Lauren M., Lacker, Caitlin R., Reisman, Sarah E.   +3 more
core   +1 more source

Site-selective α-C(sp3)–H arylation of dialkylamines via hydrogen atom transfer catalysis-enabled radical aryl migration

Nature Communications
Site-selective C(sp3)–H arylation is an appealing strategy to synthesize complex arene structures but remains a challenge facing synthetic chemists. Here we report the use of photoredox-mediated hydrogen atom transfer (HAT) catalysis to accomplish the ...
Jie Xu, Ruihan Li, Yijian Ma, Jie Zhu, Chengshuo Shen, Heng Jiang   +5 more
doaj   +1 more source

Synthesis of C,N'-linked bis-heterocycles using a deprotometalation-iodination-N-arylation sequence and evaluation of their antiproliferative activity in melanoma cells [PDF]

, 2014
International audienceBenzothiophene, benzofuran, benzothiazole and benzoxazole were deprotometalated using the lithium-zinc combination prepared from ZnCl2*TMEDA (TMEDA = N,N,N',N'-tetramethylethylenediamine, 1 equiv) and lithium 2,2,6,6 ...
Bentabed-Ababsa, Ghenia, Chevallier, Floris, Derdour, Aicha, Dorcet, Vincent, Florence, Mongin, Hedidi, Madani, Picot, Laurent, Roisnel, Thierry, Thiery, Valérie   +8 more
core   +3 more sources

Copper-catalyzed CuAAC/intramolecular C–H arylation sequence: Synthesis of annulated 1,2,3-triazoles

Beilstein Journal of Organic Chemistry, 2012
Step-economical syntheses of annulated 1,2,3-triazoles were accomplished through copper-catalyzed intramolecular direct arylations in sustainable one-pot reactions.
Rajkumar Jeyachandran, Harish Kumar Potukuchi, Lutz Ackermann   +2 more
doaj   +1 more source

Ru-Catalyzed C-H Arylation of Fluoroarenes with Aryl Halides [PDF]

, 2016
We gratefully acknowledge the Engineering and Physical Sciences Research Council (EPSRC, EP/I038578/1 and EP/ K039547/1) for funding and the European Research Council for a Starting Grant (to I.L.).
Bringmann G., de Meijere A., Francisco Juliá-Hernández, Gregory J. P. Perry, Igor Larrosa, Jude N. Arokianathar, Marco Simonetti, Xacobe C. Cambeiro   +7 more
core   +7 more sources

Research on synthesis of microwave‐assisted heterocyclic compounds with eco‐friendly solvents and transition metals via C–H activation

Bulletin of the Korean Chemical Society, EarlyView.
This review summarizes microwave‐assisted transition‐metal catalysis for constructing N‐ and O‐heterocycles, highlighting rapid C–H and pre‐activated C–X activation, improved selectivity, and green synthetic efficiency. Abstract Microwave‐assisted organic synthesis provides a rapid and sustainable platform for synthesizing various heterocycles ...
Woo‐Jin Park, Ye Ri Han, Hyejeong Lee
wiley   +1 more source