A cooperative Pd-Cu system for direct C-H bond arylation [PDF]
, 2014 The authors are grateful to the Royal Society (University Research Fellowship to CSJC) for financial support.A novel and efficient method for C-H arylation using well-defined Pd- and Cu-NHC systems has been developed.
Cazin, Catherine +3 more
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Sulfur Mediated Allylic C-H Arylation, Epoxidation and Aziridination [PDF]
, 2019 Transition-metal-free, sulfur mediated allylic C-H arylation, epoxidation and aziridination were realized through one-pot procedures. The reaction design involved initial addition between olefins and triflic anhydride activated sulfoxides, followed by ...
Gang, Hu, Hang, Luo, Pingfan, Li
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Development of and Mechanistic Insights into Palladium-Catalyzed C-H Arylation Reactions. [PDF]
Biaryls are important targets for numerous applications in organic synthesis. As a result, the development of metal-mediated aryl cross-coupling has been extensively studied. The disadvantage of this approach is the requirement for each coupling partner
Deprez, Nicholas R.
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Palladium-Catalyzed C–H Arylation of 1,2,3-Triazoles
Molecules, 2016 Palladium(II) acetate, in combination with triphenylphosphine, catalyzes direct arylation of 1,4-disubstituted 1,2,3-triazoles effectively. This C–H arylation reaction provides facile access to fully substituted triazoles with well-defined regiochemistry.
Chengwei Zhang, Lin You, Chuo Chen
doaj +1 more source
Beilstein Journal of Organic Chemistry, 2020 An efficient synthesis of tetrabenzo[a,d,j,m]coronene derivatives having alkyl and alkoxy substituents at the 3, 6, 13, and 16-positions was achieved based on the ruthenium-catalyzed coupling reactions of anthraquinone derivatives with arylboronates via ...
Seiya Terai +3 more
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Palladium-catalyzed α-arylation of arylketones at low catalyst loadings [PDF]
, 2014 The authors thank the ERC (Advanced Researcher award-FUNCAT), 7th Framework Program NMP2-LA-2010–246461 (SYNFLOW) and King Saud University for funding.A general catalytic protocol for the a-arylation of aryl ketones has been developed.
Nolan, Steven Patrick +10 more
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Ligand-Enabled Palladium(II)-Catalyzed γ-C(sp3)−H Arylation of Primary Aliphatic Amines [PDF]
, 2023 Amines are common scaffolds in bioactive molecules as well as building blocks for chemical synthesis. Despite significant advances in palladium-catalyzed C(sp3)−H functionalization of amines over the past decades, it remains challenging to perform ...
Lei, Jiao, Chen-Hui, Yuan
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Direct C–H Alpha Arylation of Enones with ArI(O2CR)2 Reagents [PDF]
, 2019 Herein, we report the metal-free direct C–H arylation of enones mediated by hypervalent iodine reagents. The reaction proceeds via a reductive iodonium Claisen rearrangement of in situ b-pyridinium silyl enol ethers.
Felipe Cesar Sousa e Silva (7520025) +5 more
core +2 more sources
A Dual Catalytic Platform for Enabling sp3 α C–H Arylation & Alkylation of Benzamides [PDF]
, 2019 A dual catalytic sp3 a C–H arylation & alkylation of benzamides with organic halides is described. This protocol exhibits excellent chemoselectivity and exquisite site-selectivity, offering a complementary reactivity mode to existing sp3 arylation or ...
Jessica, Giacoboni +5 more
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Regioselective Direct C−H Bond (Hetero)arylation of Thiazoles Enabled by a Novel Iminopyridine-Based α‐Diimine Nickel(II) Complex Evaluated by DFT Studies. [PDF]
, 2023 Direct C−H bond arylation is a highly effective method for synthesizing arylated heteroaromatics. This method reduces synthetic steps and minimizes the formation of impurities. We report an air and moisture-stable iminopyridine-based α-diimine nickel (II)
John , Michael O. Cue +9 more
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