Results 51 to 60 of about 19,520 (191)

Synthesis of Elaborate Benzofuran-2-Carboxamide Derivatives through a Combination of 8-Aminoquinoline Directed C–H Arylation and Transamidation Chemistry

Molecules, 2020
Herein, we present a short and highly modular synthetic route that involves 8-aminoquinoline directed C−H arylation and transamidation chemistry, and which enables access to a wide range of elaborate benzofuran-2-carboxamides.
Michael Oschmann, Linus Johansson Holm, Monireh Pourghasemi-Lati, Oscar Verho   +3 more
doaj   +1 more source

Synthesis of Solution-Phase Phosphoramidite and Phosphite Ligand Libraries and Their In Situ Screening in the Rhodium-Catalyzed Asymmetric Addition of Arylboronic Acids [PDF]

, 2007
Herein, we report the automated parallel synthesis of solution-phase libraries of phosphoramidite ligands for the development of enantioselective catalysts.
Feringa, Ben L.,, Jagt, Richard B.C.,, Minnaard, Adriaan J.,, Schudde, Ebe P.,, Toullec, Patrick Y.,, Vries, Johannes G. de,   +5 more
core   +1 more source

The Challenging P‐Alkylation of Aromatic Phosphorus Heterocycles and Follow‐Up Reactions

ChemistryEurope, EarlyView.
P‐alkylation of λ3σ2‐phosphinines is hindered by weak nucleophilicity and scarce synthetic access, previously requiring multistep routes or extreme electrophiles. A direct ambient‐condition method is reported using 3,5‐bis(trimethylsilyl)‐phosphinine/B(C6F5)3 with esters or iso(thio)cyanates to generate stable 1‐R‐phosphininium salts.
Samantha Frank, Ádám Horváth, Duy Nguyen, Moritz J. Ernst, Simon Steinhauer, Zoltán Benkő, Christian Müller   +6 more
wiley   +1 more source

Хлорфенолы в органическом синтезе [PDF]

, 2016
Received: 17.08.2016; accepted: 11.10.2016; published: 01.12.2016.Поступило: 17.08.2016; приянято: 11.10.2016; опубликовано: 01.12.2016.This article reviews the alternatives for modifications of p-chlorophenols, p-chloroanisoles with the formation of C-C,
Ivanova, E. A., Mitin, V. V., Morzherin, Yu. Yu., Prokhorova, P. E., Иванова, Е. А., Митин, В. В., Моржерин, Ю. Ю., Прохорова, П. Е.   +7 more
core   +1 more source

Shedding Light on Synthetic Autocatalysis: From Conventional Closed‐Shell Chemistries to Overlooked Open‐Shell Occurrences

Chemistry – A European Journal, EarlyView.
Why add another catalyst when the product itself holds the power to catalyze its own formation? Autocatalysis in synthetic chemistry enhances reaction efficiency and uncovers novel catalytic behavior across both closed‐shell and open‐shell systems, expanding reactivity and enabling innovative design strategies.
Jaspreet Kaur, Joshua P. Barham
wiley   +1 more source

Pyridylidene ligand facilitates gold-catalyzed oxidative C–H arylation of heterocycles

Beilstein Journal of Organic Chemistry, 2015
Triaryl-2-pyridylidene effectively facilitates the gold-catalyzed oxidative C–H arylation of heteroarenes with arylsilanes as a unique electron-donating ligand on gold.
Kazuhiro Hata, Hideto Ito, Yasutomo Segawa, Kenichiro Itami   +3 more
doaj   +1 more source

Pd(II)‐Catalyzed Strategies for the β‐Arylation of α‐Amino Acids: An Overview

Chemistry – A European Journal, EarlyView.
The graphical abstract summarizes the review “Pd(II)‐Catalyzed Strategies for the β‐Arylation of α‐Amino Acids: An Overview”, highlighting representative Pd(II)‐catalyzed methods for the β‐arylation of α‐amino acids. Key mechanistic features, substrate diversity, and synthetic relevance of these transformations are showcased. Abstract Metal‐catalyzed C─
Davide Illuminati, Claudio Trapella, Vinicio Zanirato, Virginia Cristofori, Anna Fantinati   +4 more
wiley   +1 more source

Site-Selective C−H Arylation of Primary Aliphatic Amines Enabled by a Catalytic Transient Directing Group [PDF]

, 2016
Transition-metal-catalysed direct C–H bond functionalization of aliphatic amines is of great importance in organic and medicinal chemistry research. Several methods have been developed for the direct sp3 C–H functionalization of secondary and tertiary ...
Ge, Haibo, Liu, Yongbing
core   +1 more source

Methyl on the Bridge: 2‐Methyl Propellane as Precursor for 1,3‐Substituted 2‐Methylated Bicyclo[1.1.1]Pentanes

Chemistry – A European Journal, EarlyView.
The synthesis of 2‐methyl propellane and its conversion to various 1,2‐ and 1,2,3‐di‐ and trisubstituted bicyclopentanes is reported. Abstract Bicyclo[1.1.1]pentanes (BCPs) have emerged as isosteric replacements for mono‐ and para‐substituted benzene rings in medicinal and materials applications, involving substitution at the BCP bridgehead (1,3 ...
Sean R. Verschaeve, Mariana Gomes Manso, Tibo Van Eeckhoorn, Mark E. Light, Bruno Linclau   +4 more
wiley   +1 more source

Phosphine-Free Palladium-Catalyzed Direct C-3 Arylation of 2-Phenylimidazo[1,2-a]pyridine Using Silver(I) Carboxylate

Journal of Chemistry, 2013
Phosphine-free palladium-catalyzed direct arylation of 2-phenyl-imidazo[1,2-a]pyridine has been developed with the concept of using silver(I) carboxylate.
Sridevi Kona, Rama Suresh Ravi, Manab Chakravarty, Venkata N. R. Chava   +3 more
doaj   +1 more source