Results 141 to 150 of about 219,259 (216)

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Cyclometalated Platinum Compounds from Competing C–H/C–X Bond Activation Pathways

ACS Omega
Craig M. Anderson, Matthew W. Greenberg, Christopher N. LaFratta, Monika Dziubelski, Zainab Aleem, Benett B. Hathaway, Joseph M. Tanski   +6 more
doaj   +1 more source

Pd@PdBO<i>_x</i> heterostructure with strong electronic interaction to promote C─H bond activation for glycerol oxidation reaction. [PDF]

Sci Adv
Li Z, Jiang K, Yang Y, Pian Y, Liu H, Zheng Z, Wang X, Jana S, Li J, Ma Z, Qiao X, Zou X, Ma X, Zhang B, Chu H, Wu YA.   +15 more
europepmc   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Remote C─H Bond Activation via Enantioselective Carbopalladation and 1,4-Pd Migration Cascade Process. [PDF]

Adv Sci (Weinh)
Xu B, Ji D, Zhang ZM, Zhang J.
europepmc   +1 more source

C-H Bond Activation Mechanism by a Pd(II)-(μ-O)-Au(0) Structure Unique to Heterogeneous Catalysts. [PDF]

JACS Au, 2022
Takei D, Yatabe T, Yabe T, Miyazaki R, Hasegawa JY, Yamaguchi K.   +5 more
europepmc   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Mechanism of Oxidative C─H Bond Activation by De Novo Designed Artificial Cu Metalloenzymes Using H₂O₂ and O₂. [PDF]

Chemistry
Prakash D, Wu Y, Misra SK, Sampath N, Wang B, Chakraborty S.   +5 more
europepmc   +1 more source

Ru(II)-Catalyzed Hydroarylation of in situ Generated 3,3,3-Trifluoro-1-propyne by C-H Bond Activation: A Facile and Practical Access to β-Trifluoromethylstyrenes. [PDF]

Chemistry, 2022
Vuagnat M, Tognetti V, Jubault P, Besset T.   +3 more
europepmc   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source