Results 161 to 170 of about 28,139,687 (262)

Aerobic C-H bond activation at a Pd center under aqueous conditions. [PDF]

Chem Sci
Bae DY, Ruhs NP, Mirica LM.
europepmc   +1 more source

Efficient Screening of Metal Promoters of Pt Catalysts for C-H Bond Activation in Propane Dehydrogenation from a Combined First-Principles Calculations and Machine-Learning Study. [PDF]

ACS Omega, 2023
Zhou N, Liu W, Jan F, Han Z, Li B.
europepmc   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Circular Low-Carbon Ammonia Synthesis Enabled by Microwave-Induced CH Bond Activation Reactions. [PDF]

ChemSusChem
Desta BK, Baddam SR, Tewari K, Chen Y, Luo C, Robinson B, Araia A, Sanyal O, Wang Y, Tian Y, Hu J.   +10 more
europepmc   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Formation of charge-polarized regions at dual single-atom sites for C-H bond activation in methane. [PDF]

Nat Commun
Chen D, Zhou J, Lyu W, Zhao X, Fang R, Wang F, Li Y.   +6 more
europepmc   +1 more source

Stability and C-H Bond Activation Reactions of Palladium(I) and Platinum(I) Metalloradicals: Carbon-to-Metal H-Atom Transfer and an Organometallic Radical Rebound Mechanism. [PDF]

J Am Chem Soc, 2023
Krämer T, Gyton MR, Bustos I, Sinclair MJG, Tan SY, Wedge CJ, Macgregor SA, Chaplin AB.   +7 more
europepmc   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Basicity-Controlled C-H Bond Activation by a Structurally Characterized Ni(III)-Hydroxo Complex. [PDF]

J Am Chem Soc
Pan HR, Wu J, Tsai CM, Liao PJ, Hsu HF.
europepmc   +1 more source

Adsorption of Polycyclic Aromatic Hydrocarbons and C₆₀ onto Forsterite: C-H Bond Activation by the Schottky Vacancy. [PDF]

ACS Earth Space Chem, 2022
Campisi D, Lamberts T, Dzade NY, Martinazzo R, Ten Kate IL, Tielens AGGM.   +5 more
europepmc   +1 more source