Results 181 to 190 of about 28,139,687 (262)

Base-Promoted Iridium-Catalyzed Deuteration and C-H Bond Activation of <i>N</i>-Heterocycles. [PDF]

open access: yesJ Org Chem
Tickner BJ   +5 more
europepmc   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Cyclometalated Platinum Compounds from Competing C–H/C–X Bond Activation Pathways

open access: yesACS Omega
Craig M. Anderson   +6 more
doaj   +1 more source

Palladium-mediated ligand-directed C–H bond activation and halogenation by mechanochemistry

open access: yes
Izravno i selektivno uvođenje funkcionalnih skupina postignuto zamjenom inertnih veza C–H jedan je od sintetskih koraka u pripremi brojnih organskih spojeva.
Barišić, Dajana
core  

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Mechanistic Insights into Iron-Catalyzed C-H Bond Activation and C-C Coupling. [PDF]

open access: yesOrganometallics, 2021
Brewer SM   +7 more
europepmc   +1 more source

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