Intermolecular Radical C–H Bond Activation: A Powerful Tool for Late Stage Functionalization
CHIMIA, 2020 The synthesis of complex molecules via radical reactions involving carbon–carbon and carbon–heteroatom bonds has become a very successful approach. Radical chemistry has long been dominated by the use of tin-based reagents.
Fabrice Dénès
doaj +1 more source
Selective activation of CH bond of phenol in ortho-position into COH bond in a two-phase system
Catalysis Communications, 2021 A method for the selective activation of CH bond of phenol in ortho-position into C-OH bond was developed at room temperature over Cu2+ ions in a two-phase system using marginally water-soluble polar alcohols, acetonitrile and water as solvents and ...
Ke Zheng +4 more
doaj +1 more source
Metal Nanoparticles as Sustainable Tools for C–N Bond Formation via C–H Activation
Molecules, 2021 The design of highly active metal nanoparticles to be employed as efficient heterogeneous catalysts is a key tool for the construction of complex organic molecules and the minimization of their environmental costs.
Federica Valentini +2 more
doaj +1 more source
Lead-free B-site bimetallic perovskite photocatalyst for efficient benzylic C–H bond activation
Cell Reports Physical Science, 2021 Summary: Although bismuth (Bi)-based halide perovskites have attracted profound attention in photocatalysis, the undesirable photophysical properties are not well modulated, and the effect of surface structure on adsorption and activation of reactant ...
Ming Shi +7 more
doaj +1 more source
Ligand Accelerated Hydrogen Isotope Exchange: Switching C-H Activation from Functionalization Towards C-D Bond Formation [PDF]
, 2023 Hydrogen isotope exchange (HIE) has emerged as a unique strategy for labelling, affording plenty of deuterated chemicals with varieties in patterns.
Jianfei, Bai +6 more
core +2 more sources
Computational exploration of the reaction mechanism of the Cu+-catalysed synthesis of indoles from N-aryl enaminones [PDF]
Royal Society Open Science, 2016 We have studied the role of Cu+-phenantroline as a catalyst in the cyclization of N-aryl-enaminones using density-functional theory computations. The catalyst was found to bind the substrate upon deprotonation of its eneaminone, and to dramatically ...
Carlos E. P. Bernardo, Pedro J. Silva
doaj +1 more source
Systematic Assessment of the Catalytic Reactivity of Frustrated Lewis Pairs in C-H Bond Activation
Molecules, 2023 Unreactive C-H bond activation is a new horizon for frustrated Lewis pair (FLP) chemistry. This study provides a systematic assessment of the catalytic reactivity of recently reported intra-molecular FLPs on the activation of typical inert C-H bonds ...
Yongjie Guo +7 more
doaj +1 more source
Introducing Ion Mobility Mass Spectrometry to Identify Site-Selective C–H Bond Activation in N-Heterocyclic Carbene Metal Complexes [PDF]
, 2022 The activation of C−H bonds in a selective manner still constitutes a major challenge from a synthetic point of view; thus, it remains an active area of fundamental and applied research. Herein, we introduce ion mobility spectrometry mass spectrometry-
Ibañez-Ibañez, Laura +13 more
core +1 more source
Ni-catalyzed benzylic β-C(sp3)–H bond activation of formamides
Nature Communications, 2022 The development of 3d-metal-catalyzed β-C–H bond activation via 4-membered metallacycles remains an elusive challenge. Here, the authors report a Ni-Al bimetal-catalyzed β-C(sp3)–H bond activation of formamides via 4-membered nickelacycles.
Rong-Hua Wang +7 more
doaj +1 more source
C–H Functionalization via Iodine-mediated Electrocatalysis and C–N Bond Formation [PDF]
, 2022 The access of heterocyclic compounds via direct amination of C-H bonds are of vital interest because of their role in pharmaceutical and natural products. The combination of molecular iodine and electricity activates benzylic C-H bond and facilitates the
Guilherme. M., Martins +3 more
core +1 more source