Results 41 to 50 of about 28,139,687 (262)

Heterolytic bond activation at gold: Evidence for gold(III) H-B, H-Si complexes, H-H and H-C cleavage [PDF]

, 2019
The coordinatively unsaturated gold(III) chelate complex [(C^N-CH)Au(C6F5)]+ (1+) reacts with main group hydrides H-BPin and H-SiEt3 in dichloromethane solution at 70 °C to form the corresponding σ-complexes, which were spectroscopically characterized (C^
Budzelaar, Peter, Bochmann, Manfred, Bochmann M., Rocchigiani L., Budzelaar P. H. M., Rocchigiani, Luca   +5 more
core   +1 more source

Cobalt-catalyzed directed C–H alkenylation of pivalophenone N–H imine with alkenyl phosphates

Beilstein Journal of Organic Chemistry, 2018
A cobalt–N-heterocyclic carbene (NHC) catalyst efficiently promotes an ortho C–H alkenylation reaction of pivalophenone N–H imine with an alkenyl phosphate. The reaction tolerates various substituted pivalophenone N–H imines as well as cyclic and acyclic
Wengang Xu, Naohiko Yoshikai
doaj   +1 more source

Tracking C-H activation with orbital resolution [PDF]

, 2023
The reactivity towards C-H bond activation of alkanes with transition metals is determined by the ability of the metal to donate and withdraw electron density in due proportion.
Dmitry, Ozerov, Torsten, Leitner, Christopher, Arrell, Raphael, Jay, Victoria, Kabanova, Philip, Johnson, Jessica, Harich, Camila, Bacellar, Ambar, Banerjee, Christopher, Milne, Nils, Huse, Grigory, Smolentsev, Michael, Coates, Anna, Wach, Claudio, Cirelli, Michael, Odelius, Robert, Stefanuik, Camelia, Borca, Ru-Pan, Wang, Thomas, Huthwelker, Hampus, Wikmark, Abdullah, Kahraman, Emma, Beale, Philippe, Wernet   +23 more
core   +2 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

C–H Activation via Group 8–10 Pincer Complexes: A Mechanistic Approach

Inorganics
C–H bond activation is a crucial synthetic strategy widely utilized in both academic and industrial settings. Due to the strong and kinetically inert nature of the C–H bond, its functionalization typically requires metal-based catalysts.
Juan S. Serrano-García, Andrés Amaya-Flórez, Jordi R.-Galindo, Lucero González-Sebastián, Luis Humberto Delgado-Rangel, David Morales-Morales   +5 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Advances in the Synthesis of Fluorinated Scaffolds by Transition Metal-Catalyzed C–H Bond Activation [PDF]

, 2020
International audienceThanks to the unique features of the fluorine atom and the fluorinated groups, fluorine-containing molecules are essential. Therefore, the search for new fluorinated groups as well as straightforward and original methodologies for ...
Mazeh, Sara, Besset, Tatiana, Lapuh, María Ivana   +2 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

The Activating Effect of Strong Acid for Pd-Catalyzed Directed C–H Activation by Concerted Metalation-Deprotonation Mechanism

Molecules, 2021
A computational study on the origin of the activating effect for Pd-catalyzed directed C–H activation by the concerted metalation-deprotonation (CMD) mechanism is conducted.
Heming Jiang, Tian-Yu Sun
doaj   +1 more source

Chemoselective C–C σ-Bond Activation of Biphenylene [PDF]

, 2020
The chemoselective cleavage of an arene ring in biphenylene is reported using an aluminium(I) complex. The reaction proceeds with complete integrity of the central 4-membered ring despite this ring containing the weakest C–C σ-bond in the hydrocarbon ...
Mark, Crimmin, Richard Y, Kong
core   +2 more sources