Results 181 to 190 of about 52,780 (297)
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Late-Stage Aromatic C-H Bond Functionalization for Cysteine/Selenocysteine Bioconjugation. [PDF]
Zhao Z +7 more
europepmc +1 more source
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Site-Selective C─H Bond Functionalization of Sugars. [PDF]
Stepanova EV +4 more
europepmc +1 more source
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
Nile Red-Based Covalent Organic Framework as a Photocatalyst for C-H Bond Functionalization. [PDF]
Gordo-Lozano M +6 more
europepmc +1 more source
O-Acetyl Oximes as Transformable Directing Groups for Pd-Catalyzed C−H Bond Functionalization
Sharon R. Neufeldt, Melanie S. Sanford
openalex +2 more sources
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
β-C-H bond functionalization of ketones and esters by cationic Pd complexes. [PDF]
Li YH, Chekshin N, Lu Y, Yu JQ.
europepmc +1 more source

