Results 181 to 190 of about 27,304,717 (282)

Unlocking Terpenoid Transformations: C-H Bond Functionalization for Methyl Group Substitution, Elimination, and Integration. [PDF]

ACS Cent Sci
Murray LAM.
europepmc   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Substitution, Elimination, and Integration of Methyl Groups in Terpenes Initiated by C-H Bond Functionalization. [PDF]

ACS Cent Sci
Kang YC, Wetterer RT, Karimov RR, Kojima M, Surke M, Martín-Torres I, Nicolai J, Elkin M, Hartwig JF.   +8 more
europepmc   +1 more source

Palladium-catalyzed direct asymmetric C-H bond functionalization enabled by the directing group strategy. [PDF]

Chem Sci, 2020
Yang K, Song M, Liu H, Ge H.
europepmc   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Connecting remote C-H bond functionalization and decarboxylative coupling using simple amines. [PDF]

Nat Chem, 2020
de Azambuja F, Yang MH, Feoktistova T, Selvaraju M, Brueckner AC, Grove MA, Koley S, Cheong PH, Altman RA.   +8 more
europepmc   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

In-situ noncovalent interaction of ammonium ion enabled C-H bond functionalization of polyethylene glycols. [PDF]

Nat Commun
Zhang Z, Lv X, Mu X, Zhao M, Wang S, Ke C, Ding S, Zhou D, Wang M, Zeng R.   +9 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Transition-Metal-Catalyzed Directed C-H Bond Functionalization with Iodonium Ylides: A Review of the Last 5 Years. [PDF]

Molecules
Liao J, Kong D, Gao X, Zhai R, Chen X, Wang S.   +5 more
europepmc   +1 more source