Undirected, Homogeneous C-H Bond Functionalization: Challenges and Opportunities. [PDF]
ACS Cent Sci, 2016 The functionalization of C–H bonds has created new approaches to preparing organic molecules by enabling new strategic “disconnections” during the planning of a synthetic route.
Hartwig JF, Larsen MA.
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ACS Catalysis, 2020 Transition-metal-catalyzed C–H bond functionalization has known a rapid evolution in the last years, offering modern strategies for reaching high molecular complexity in a step- and atom-economical...
Tatiana Besset
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Ruthenium-Catalyzed C–H Bond Functionalization in Cascade and One-Pot Transformations
Coordination Chemistry Reviews, 2021 Ruthenium complexes are well known as remarkable pre-catalysts for challenging C–H bond functionalizations. Combining them with other types of chemical reactions in a tandem or one-pot fashion is appealing from a sustainable point of view because it ...
Rafael Gramage-Doria, Christian Bruneau
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Evolution of C-H Bond Functionalization from Methane to Methodology. [PDF]
J Am Chem Soc, 2016 This Perspective presents the fundamental principles, the elementary reactions, the initial catalytic systems, and the contemporary catalysts that have converted C−H bond functionalization from a curiosity to a reality for synthetic chemists.
Hartwig JF.
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A Perspective on Late-Stage Aromatic C-H Bond Functionalization. [PDF]
J Am Chem Soc, 2022 Late-stage functionalization of C–H bonds (C–H LSF) can provide a straightforward approach to the efficient synthesis of functionalized complex molecules.
Zhang L, Ritter T.
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Recent Advances in Regioselective C-H Bond Functionalization of Free Phenols. [PDF]
Molecules, 2023 Phenols are important readily available synthetic building blocks and starting materials for organic synthetic transformations, which are widely found in agrochemicals, pharmaceuticals, and functional materials.
Li Y, Huang Y, Li Z, Sun J.
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C–H bond functionalization reactions enabled by photobiocatalytic cascades
Green Synthesis and Catalysis, 2021 Light may participate in biocatalytic processes either by direct light-induced biocatalysis or by cascading light-induced chemical reactions with biocatalytic ones, which are acknowledged as photocatalysis.
Yuanying Li +3 more
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Biocatalytic, Intermolecular C-H Bond Functionalization for the Synthesis of Enantioenriched Amides. [PDF]
Angew Chem Int Ed Engl, 2021 Directed evolution of heme proteins has opened access to new-to-nature enzymatic activity that can be harnessed to tackle synthetic challenges. Among these, reactions resulting from active site iron-nitrenoid intermediates present a powerful strategy to ...
Athavale SV +5 more
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C-H Bond Functionalization of Amines: A Graphical Overview of Diverse Methods. [PDF]
SynOpen, 2021 This Graphical Review provides a concise overview of the manifold and mechanistically diverse methods that enable the functionalization of sp3 C–H bonds in amines and their derivatives.
Dutta S +4 more
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Synthesis of Benzo[4,5]thiazolo[2,3-c][1,2,4]triazole Derivatives via C-H Bond Functionalization of Disulfide Intermediates. [PDF]
Molecules, 2022 Many nitrogen- and sulfur-containing heterocyclic compounds exhibit biological activity. Among these heterocycles are benzo[4,5]thiazolo[2,3-c][1,2,4]triazoles for which two main synthetic approaches exist.
Ardón-Muñoz LG, Bolliger JL.
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