Results 31 to 40 of about 27,070,838 (300)
Nature Communications, 2022 Methods to functionalize inert C–H bonds are a critical focus of synthetic organic chemistry. In this work the authors use computations and experiments to uncover the mechanisms of palladium-catalysed C–H lactonizations in aromatic carboxylic acids, and ...
Li-Ping Xu +4 more
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Distal Functionalization via Transition Metal Catalysis
Chemistry Proceedings, 2022 The ubiquitous presence of sp3 C−H bonds in natural feedstock makes them inexpensive, easily accessible, and attractive synthons for the preparation of common and/or complex molecular frameworks in biologically active natural products, pharmaceutics ...
Haibo Ge
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, 2023 International audienceThe last decade has witnessed the emergence of innovative synthetic tools for the synthesis of fluorinated molecules. Among these approaches, the transition metal catalyzed functionalization of various scaffolds with a panel of ...
Besset, Tatiana +2 more
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Organophotoredox-Catalyzed Direct C-H Functionalization of “Drug Prejudice” at Room Temperature [PDF]
, 2020 Organophotocatalytic C─H bond functionalization has attracted lot of attention in the past several years due to the possibility of catalysing reactions in a metal-free environment.
Narendra, Chaubey +2 more
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Synthesis of Phthalides and α,β-butenolides by Transition Metal-Catalyzed Activation of C—H Bonds
Molecules, 2019 Phthalides and α,β-butenolides are two related classes of oxygenated heterocycles with a wide range of biological activities. An innovative strategy to prepare these compounds is based on C—H bond functionalization reactions, in which two
Andrea Renzetti, Kozo Fukumoto
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Multiple Catalytic C-H Bond Functionalization for Natural Product Synthesis [PDF]
, 2020 In the past decade, multiple catalytic C-H bond functionalization has been successfully applied in natural product synthesis as a strategy to reduce the number of steps, increase overall yield and employ more easily available starting materials.
Baudoin, Olivier
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Green Synthesis and Catalysis, 2023 Disclosed herein is a novel Rh/Ag co-catalyzed SNH directed C–H activation and C–H/N–H bond functionalization protocol of free NH-sulfoximines with hypervalent iodonium ylides.
Jiapian Huang +4 more
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Evolution of C-H Bond Functionalization from Methane to Methodology. [PDF]
J Am Chem Soc, 2016 This Perspective presents the fundamental principles, the elementary reactions, the initial catalytic systems, and the contemporary catalysts that have converted C-H bond functionalization from a curiosity to a reality for synthetic chemists.
Hartwig JF.
europepmc +2 more sources
C−H Bond Functionalization under Electrochemical Flow Conditions
The Chemical Record, 2022 AbstractElectrochemical C−H functionalization is a rapidly growing area of interest in organic synthesis. To achieve maximum atom economy, the flow electrolysis process is more sustainable. This allows shorter reaction times, safer working environments, and better selectivities.
Tamlal Pokhrel +4 more
openaire +2 more sources
Radical‐Promoted Distal C‐H Functionalization of C(sp3) Centers with Fluorinated Moieties
, 2020 International audienceDue to their unique properties, fluorinated scaffolds are pivotal compounds in pharmaceuticals, agrochemicals and materials science.
Tatiana Besset +5 more
core +1 more source