Results 31 to 40 of about 29,149,024 (329)
Multiple Catalytic C-H Bond Functionalization for Natural Product Synthesis.
Angewandte Chemie, 2020 In the past decade, multiple catalytic C-H bond functionalization has been successfully applied in natural product synthesis as a strategy to reduce the number of steps, increase overall yield and employ more easily available starting materials.
O. Baudoin
semanticscholar +1 more source
Angewandte Chemie, 2022 Direct C-H bond functionalization is a useful strategy for the straightforward formation of C-C and C-Heteroatom bonds. In the present work, a unique approach for the challenging electrophilic Au-catalyzed α- C-H bond functionalization of tertiary amines
David Fabian León Rayo +4 more
semanticscholar +1 more source
Coumarins Synthesis and Transformation via C–H Bond Activation—A Review
Inorganics, 2022 For several decades, coumarins have attracted considerable attention due to the fact of their application in diverse fields such as medical science and biomedical research as well as several industrial branches.
Katarzyna Szwaczko
doaj +1 more source
Arenes and Heteroarenes C–H Functionalization Under Enabling Conditions: Electrochemistry, Photoelectrochemistry & Flow Technology [PDF]
, 2023 C-H bond functionalization generates molecular complexity in single-step transformation. However, the activation of C-H bonds requires expensive metals or stoichiometric amounts of oxidizing/reducing species.
Ayesha , Murtaza +6 more
core +1 more source
A Simple Access to γ‐ and ε‐Keto Arenes via Enzymatic Divergent C─H Bond Oxyfunctionalization
Advanced Science, 2023 Performing divergent C─H bond functionalization on molecules with multiple reaction sites is a significant challenge in organic chemistry. Biocatalytic oxyfunctionalization reactions of these compounds to the corresponding ketones/aldehydes are typically
Huanhuan Li +6 more
doaj +1 more source
C–H Functionalization via Iodine-mediated Electrocatalysis and C–N Bond Formation [PDF]
, 2022 The access of heterocyclic compounds via direct amination of C-H bonds are of vital interest because of their role in pharmaceutical and natural products. The combination of molecular iodine and electricity activates benzylic C-H bond and facilitates the
Guilherme. M., Martins +3 more
core +1 more source
Nature Communications, 2022 Methods to functionalize inert C–H bonds are a critical focus of synthetic organic chemistry. In this work the authors use computations and experiments to uncover the mechanisms of palladium-catalysed C–H lactonizations in aromatic carboxylic acids, and ...
Li-Ping Xu +4 more
doaj +1 more source
Distal Functionalization via Transition Metal Catalysis
Chemistry Proceedings, 2022 The ubiquitous presence of sp3 C−H bonds in natural feedstock makes them inexpensive, easily accessible, and attractive synthons for the preparation of common and/or complex molecular frameworks in biologically active natural products, pharmaceutics ...
Haibo Ge
doaj +1 more source
, 2023 International audienceThe last decade has witnessed the emergence of innovative synthetic tools for the synthesis of fluorinated molecules. Among these approaches, the transition metal catalyzed functionalization of various scaffolds with a panel of ...
Besset, Tatiana +2 more
core +1 more source
Imine as a Linchpin Approach for Distal C(sp2)–H Functionalization [PDF]
, 2020 Despite the widespread applications of C–H functionalization, controlling site selectivity remains a significant challenge. Covalently attached directing group (DG) served as an ancillary ligand to ensure proximal ortho-, distal meta- and para-C-H ...
Sadhan, Jana +6 more
core +2 more sources