Results 41 to 50 of about 27,070,838 (300)

A general strategy for C(sp3)–H functionalization with nucleophiles using methyl radical as a hydrogen atom abstractor [PDF]

, 2021
Photoredox catalysis has provided many approaches to C(sp3)-H functionalization that enable selective oxidation and C(sp3)-C bond formation via the intermediacy of a carbon-centered radical. While highly enabling, functionalization of the carbon-centered
Isabelle, Leibler, Abigail, Doyle, Leibler, Isabelle Nathalie-Marie, Tekle-Smith, Makeda A, Doyle, Abigail G, Makeda A., Tekle-Smith   +5 more
core   +3 more sources

Robust molecular trends in Pd-catalyzed C(sp2/sp3)-H activation reactions – A review

Results in Chemistry, 2021
Direct functionalization of inert C–H bonds into various C-X (X = C, N, O, S) functionalities is one of the frontier research topics and regularly gaining popularities among the communities of scientists by providing opportunities for direct synthesis of
Pravati Panda, Kaushik Pal, Subhendu Chakroborty   +2 more
doaj   +1 more source

Stereoselective C−B and C−H Bonds Functionalization of polyBorylated Alkenes [PDF]

, 2023
Alkenes are fundamental functional groups which feature in various materials and bioactive molecules; however, efficient divergent strategies for their stereodefined synthesis are difficult.
Narendra K., Vaishanv, Nadim, Eghbarieh, Ahmad, Masarwa, Rahul A., Jagtap   +3 more
core   +1 more source

Silver-Mediated Direct sp(3) C-H Bond Functionalization

, 2015
Direct sp(3) C-H bond functionalization is an efficient, straightforward, and powerful method to construct new C-X (X = C, N, F, S) bonds from nonfunctionalized aliphatic motif of organic molecules, which has been used in late-stage modification of ...
Zhou, Taigang, Zhang-Jie Shi, Shi, Zhang-Jie, Taigang Zhou   +3 more
core   +1 more source

Recent Advances in the Nickel-Catalyzed Alkylation of C-H Bonds

Molecules
Functionalization of C-H bonds has emerged as a powerful strategy for converting inert, nonfunctional C-H bonds into their reactive counterparts.
Franc Požgan, Uroš Grošelj, Jurij Svete, Bogdan Štefane, Hamad H. Al Mamari   +4 more
doaj   +1 more source

An Atomically Dispersed Photocatalyst for para-Selective C-H bond Functionalization of Electron-Poor Arenes [PDF]

Regioselective C-H bond functionalization is pivotal in modern scientific exploration, offering solutions for achieving novel synthetic methodologies and pharmaceutical development.
Suman , Pradhan, Jun , Hu, Giovanni , Barcaro, Joaquin , Silvestre-Albero, Jabor , Rabeah, Sandra , Van Aert, Susanna , Monti, Xingchao , Dai, Piotr , Kuśtrowski, Shoubhik, Das, Aleksander , Jaworski, Veronica , Celorrio, Peng , Ren, Yuman, Qin, Sara , Bals, Noopur , Jain, Anna , Rokicińska   +16 more
core   +2 more sources

Selective Dealkenylative Functionalization of Styrenes via C-C Bond Cleavage

Research, 2020
As a readily available feedstock, styrene with about 25 million tons of global annual production serves as an important building block and organic synthon for the synthesis of fine chemicals, polystyrene plastics, and elastomers.
Jianzhong Liu, Jun Pan, Xiao Luo, Xu Qiu, Cheng Zhang, Ning Jiao   +5 more
doaj   +1 more source

Site-Selective A-C-H Functionalization of Trialkylamines via Reversible Hydrogen Atom Transfer Catalysis [PDF]

, 2021
Trialkylamines are widely found in naturally-occurring alkaloids, synthetic agrochemicals, biological probes, and especially pharmaceuticals agents and pre-clinical candidates.
Franziska, Schoenebeck, Yangyang, Shen, Ignacio, Funes-Ardoiz, Tomislav, Rovis   +3 more
core   +2 more sources

Recent Developments in Transition-Metal Catalyzed Direct C–H Alkenylation, Alkylation, and Alkynylation of Azoles

Molecules, 2020
The transition metal-catalyzed C–H bond functionalization of azoles has emerged as one of the most important strategies to decorate these biologically important scaffolds. Despite significant progress in the C–H functionalization of various heteroarenes,
Su Chen, Prabhat Ranjan, Leonid G. Voskressensky, Erik V. Van der Eycken, Upendra K. Sharma   +4 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source