Ligand Accelerated Hydrogen Isotope Exchange: Switching C-H Activation from Functionalization Towards C-D Bond Formation [PDF]
, 2023 Hydrogen isotope exchange (HIE) has emerged as a unique strategy for labelling, affording plenty of deuterated chemicals with varieties in patterns.
Jianfei, Bai +6 more
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Palladium-Catalyzed C−H Bond Functionalization with Arylsulfonyl Chlorides
, 2016 Palladium-Catalyzed C−H Bond Functionalization with Arylsulfonyl ...
Vy M. Dong (1311219) +2 more
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Organophotoredox-Catalyzed Direct C-H Functionalization of “Drug Prejudice” at Room Temperature [PDF]
, 2020 Organophotocatalytic C─H bond functionalization has attracted lot of attention in the past several years due to the possibility of catalysing reactions in a metal-free environment.
Narendra, Chaubey +2 more
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Synthesis of Phthalides and α,β-butenolides by Transition Metal-Catalyzed Activation of C—H Bonds
Molecules, 2019 Phthalides and α,β-butenolides are two related classes of oxygenated heterocycles with a wide range of biological activities. An innovative strategy to prepare these compounds is based on C—H bond functionalization reactions, in which two
Andrea Renzetti, Kozo Fukumoto
doaj +1 more source
Anaerobic functionalization of unactivated C–H bonds [PDF]
Current Opinion in Chemical Biology, 2009 The functionalization of alkanes was once thought to lie strictly within the domain of enzymes that activate dioxygen in order to generate an oxidant with suitable potency to cleave inert C-H bonds. The emergence of the radical SAM superfamily of enzymes-those which use S-adenosyl-l-methionine as a precursor to a 5'-deoxyadenosyl 5'-radical-has kindled
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Green Synthesis and Catalysis, 2023 Disclosed herein is a novel Rh/Ag co-catalyzed SNH directed C–H activation and C–H/N–H bond functionalization protocol of free NH-sulfoximines with hypervalent iodonium ylides.
Jiapian Huang +4 more
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Pushing the boundaries of C–H bond functionalization chemistry using flow technology
Journal of Flow Chemistry, 2020 C–H functionalization chemistry is one of the most vibrant research areas within synthetic organic chemistry. While most researchers focus on the development of small-scale batch-type transformations, more recently such transformations have been carried ...
Sebastian Govaerts, A. Nyuchev, T. Noel
semanticscholar +1 more source
Rhodium catalyzed chelation-assisted C-H bond functionalization reactions
Accounts of Chemical Research, 2011 Conspectus Over the last several decades, researchers have achieved remarkable progress in the field of organometallic chemistry. The development of metal-catalyzed cross-coupling reactions represents a paradigm shift in chemical synthesis, and today ...
D. A. Colby +3 more
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Controlling Site Selectivity in Palladium-Catalyzed C–H Bond Functionalization
Accounts of Chemical Research, 2012 Conspectus Effective methodology to functionalize C–H bonds requires overcoming the key challenge of differentiating among the multitude of C–H bonds that are present in complex organic molecules.
S. Neufeldt, M. Sanford
semanticscholar +1 more source
C−H Bond Functionalization under Electrochemical Flow Conditions
The Chemical Record, 2022 AbstractElectrochemical C−H functionalization is a rapidly growing area of interest in organic synthesis. To achieve maximum atom economy, the flow electrolysis process is more sustainable. This allows shorter reaction times, safer working environments, and better selectivities.
Tamlal Pokhrel +4 more
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