Results 161 to 170 of about 206,495 (234)

Silver-Catalyzed C(sp3)–H Functionalization

ACS Organic & Inorganic Au
Masoud Sadeghi
doaj   +1 more source

Stereo-reversed E2 unlocks <i>Z</i>-selective C-H functionalization. [PDF]

Science
Verardi PJ, Ryutov EA, Mukherjee P, Lalisse R, Targos K, Inagaki T, Kelly M, Guzei IA, Schreier M, Gutierrez O, Wickens ZK.   +10 more
europepmc   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Undirected, Homogeneous C–H Bond Functionalization: Challenges and Opportunities

ACS Central Science, 2016
John F. Hartwig, Matthew A. Larsen
doaj   +1 more source

Chelation-assisted multiple and relay C-H functionalization of unactivated aliphatic <i>E</i>-alkenes. [PDF]

Chem Sci
Wang Y, Li X, Peng C, Chen Y, Lu X, Zhu Y, Yu P, Zhong G, Zhang J.   +8 more
europepmc   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Bimetallic [Co/K] hydrogen evolution catalyst for electrochemical terminal C-H functionalization. [PDF]

Nat Commun
Zhang S, Hong L, Feng J, Wang M, Hu J, Zhang Y, Li MB.   +6 more
europepmc   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

On-DNA C-H functionalization of electron-rich arenes for DNA-encoded libraries. [PDF]

Nat Chem
de Pedro Beato E, Torkowski L, Hartmann P, Vogelsang L, Dietz KJ, Ritter T.   +5 more
europepmc   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

FEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso, Jaime Hiniesta‐Valero, Alejandra Guerra‐Castellano, Miguel A. De la Rosa, Irene Díaz‐Moreno   +4 more
wiley   +1 more source