Results 91 to 100 of about 29,179,465 (256)

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source

Structural variability of Ag(I) metal–organic networks: C–H⋯π and metal⋯π interactions

, 2016
The synthesis and X-ray structural characterization of two silver(I) coordination polymers, [Ag2(bpp)2(Phdac)]·5H2O (1) and [Ag2(bpp)(HSSal)] (2), are reported, where bpp = 4,4′-trimethylene dipyridine, H2Phdac = 1,4-phenylenediacetic acid, and H3SSal ...
Debdoot Hazari (840247), Saikat K. Seth (840249), Horst Puschmann (840250), Swapan K. Jana (840248), Sudipta Dalai (840251)   +4 more
core   +1 more source

Crystal structure of (E)-1-(2,4-dinitrophenyl)-2-[(E)-5-phenyl-1-(p-tolyl)pent-2-en-4-yn-1-ylidene]hydrazine

Acta Crystallographica Section E: Crystallographic Communications, 2015
In the title compound, C24H18N4O4, the plane of the phenyl ring is inclined to those of the toluene ring and the dinitro-substituted benzene ring by 66.96 (19) and 47.06 (18)°, respectively, while the planes of the two benzene rings are inclined to one ...
Alexander A. Golovanov, Anna V. Vologzhanina, Evgeniya D. Voronova, Vadim V. Bekin, Sergey V. Naumov   +4 more
doaj   +1 more source

Synthesis and characterization of a mononuclear zinc(ii) Schiff base complex: on the importance of C-H⋯π interactions. [PDF]

RSC Adv, 2021
Basak T, Frontera A, Chattopadhyay S.
europepmc   +1 more source

Identification and characterization of a gene conferring stress resistance in Escherichia coli and cyanobacteria

FEBS Open Bio, EarlyView.
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada, Takaaki Tanaka, Manaka Uehara, Keigo Nakano, Ken Morishima, Rintaro Inoue, Masaaki Sugiyama, Masafumi Yohda   +7 more
wiley   +1 more source

Crystal structure and Hirshfeld surface analysis of 4-methyl-N-[2-(5-methylfuran-2-yl)phenyl]-N-[(5-phenylfuran-2-yl)methyl]benzenesulfonamide

Acta Crystallographica Section E: Crystallographic Communications
In the title compound, C29H25NO4S, the molecular conformation is stable with intramolecular C—H...O and C—H...N interactions being observed. In the crystal, molecules are linked by C—H...O interactions, forming layers parallel to the (100) plane.
Selbi Annadurdyyeva, Anastasia E. Levina, Victor N. Khrustalev, Roya Z. Nazarova, Khudayar I. Hasanov, Nurlana D. Sadikhova, Mehmet Akkurt, Gizachew Mulugeta Manahelohe   +7 more
doaj   +1 more source

Crystal structure of (7-methyl-2-oxo-2H-chromen-4-yl)methyl piperidine-1-carbodithioate

Acta Crystallographica Section E: Crystallographic Communications, 2015
In the title compound, C17H19NO2S2, the 2H-chromene ring system is nearly planar, with a maximum deviation of 0.0383 (28) Å, and the piperidine ring adopts a chair conformation.
K. R. Roopashree, T. G. Meenakshi, K. Mahesh Kumar, O. Kotresh, H. C. Devarajegowda   +4 more
doaj   +1 more source

Hydrogen bonding patterns and C-H...π interactions in the structure of the antiparkinsonian drug (R)-rasagiline mesylate determined using laboratory and synchrotron X-ray powder diffraction data. [PDF]

Acta Crystallogr B Struct Sci Cryst Eng Mater, 2023
Dugarte-Dugarte AJ, Toro RA, van de Streek J, Henao JA, Fitch AN, Dejoie C, Delgado JM, Díaz de Delgado G.   +7 more
europepmc   +1 more source

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

FEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli, Beatrice Lucia Bona, Francesca Baldelli Bombelli   +2 more
wiley   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian, Minghui Zhao, Yuanbo Hu, Kaiyue Wang, Haiguang Liu, Zetong Bai, Kebin Zheng   +6 more
wiley   +1 more source