Results 81 to 90 of about 598,727 (266)
C-H...O and C-H...π(arene) interactions in (2S,4S,5R)-(-)-2-(4-propoxyphenyl)-3,4-dimethyl-5-phenyl-1,3-oxazolidine [PDF]
, 2004 The title compound, C₂₀H₂₅NO₂, a condensation product of l-ephedrine and 4-propoxyaldehyde, is of interest in studies on weak interactions. It crystallizes with C-H...O and C-H...π(arene) intermolecular interactions as a one-dimensional chain [C...O = 3 ...
Gallagher, John F. +2 more
core +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
N-[(3-Bromo-1-phenylsulfonyl-1H-indol-2-yl)methyl]-4-fluoroaniline
IUCrData, 2017 In the title compound, C21H16BrFN2O2S, the indole ring system makes dihedral angles of 87.23 (10) and 77.58 (9)° with the fluorobenzene and phenyl rings, respectively.
C. Suresh Yadav +3 more
doaj +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Crystal structure of 2-oxo-2H-chromen-3-yl propanoate
Acta Crystallographica Section E: Crystallographic Communications, 2016 In the title compound, C12H10O4, the dihedral angle between the coumarin ring system [maximum deviation = 0.033 (8) Å] and the propionate side chain is 78.48 (8)°.
Eric Ziki +4 more
doaj +1 more source
Aromatic amino acids in peptides and proteins: novel syntheses, influences on structure, and the nature of C–H/π and S–H/π interactions [PDF]
, 2016 Zondlo, Neal J.In biology, the function of a protein or an enzyme is implicitly defined by its structure. The efficiency of a catalyst is dictated by the defined structure and chemical nature of the molecule.
Forbes, Christina R.
core +1 more source
Why human connection is the true metric of research success
FEBS Open Bio, EarlyView.Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
Crystal structure of methyl (E)-2-(1-methyl-2-oxoindolin-3-ylidene)acetate
Acta Crystallographica Section E: Crystallographic Communications, 2015 The title compound, C12H11NO3, is essentially planar, with the mean plane of the acetate side chain [–C—C(=O)—O—C] being inclined to the mean plane of the indole ring system by 12.49 (7)°.
M. P. Savithri +4 more
doaj +1 more source
Intermolecular O-H...O and C-H...π(C5H5), and intramolecular C-H...O interactions in 2-(ferrocenyl)thiophene-3-carboxylic acid [PDF]
, 2001 The title compound, [Fe(C₅H₅)(C₁₀H₇O₂S)], an important precursor en route to organometallic donor-π-acceptor systems, forms dimers in the solid state through cyclic intermolecular carboxylic acid O-H...O hydrogen bonds, graph set R²₂(8) [O...O 2.661 (2)
Gallagher, John F. +2 more
core +1 more source
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source