Results 91 to 100 of about 663,128 (258)
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
(E)-2-(3-Cinnamoylthioureido)acetic acid dimethyl sulfoxide disolvate
Acta Crystallographica Section E, 2011 In the title compound, C12H12N2O3S·2C2H6OS, the acetic acid and cinnamoyl groups adopt Z and E configurations, respectively, with respect to the thio group about the C—N bonds.
Mohammad B. Kassim +3 more
doaj +1 more source
4,4'-Di-tert-butyl-2,2'-[imidazolidine-1,3-diylbis(methyl-ene)]diphenol [PDF]
, 2013 In the title compound, C25H36N2O2, the two tert-butyl-substituted benzene rings are inclined at an angle of 53.5 (3)° to one another. The imidazolidine ring has an envelope conformation with with one of the C atoms of the ethylene fragment as the flap ...
Bolte, Michael +2 more
core +2 more sources
FEBS Open Bio, EarlyView.Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata +13 more
wiley +1 more source
Crystal structure of ethyl 3-anilino-2-{[bis(methylsulfanyl)methylidene]amino}-3-oxopropanoate
Acta Crystallographica Section E, 2014 The molecular conformation of the title compound, C14H18N2O3S2, is stabilized by intramolecular N—H...N and C—H...O hydrogen bonds. The crystal packing is characterized by a series of C—H...O hydrogen bonds, resulting in a three-dimensional network.
A. Kémish López-Rodríguez +2 more
doaj +1 more source
The Crystal and Molecular Structure of 4-Formylimidazoline-2-thione [PDF]
, 1977 The title compound is monoclinic, space group P2 Jc, with a = 4.020 (4), b = 21.491(3), c = 7-410 (4) ,4,, fl = 124.1 (5) °, Z = 4. The structure was solved by Patterson-function and heavy-atom methods from diffractometer X-ray data.
Conde Amiano, Alejandro +2 more
core +2 more sources
FEBS Open Bio, EarlyView.In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin +12 more
wiley +1 more source
1,2-Diazinium hydrogen chloranilate
Acta Crystallographica Section E, 2008 In the crystal structure of the title compound, C4H5N2+·C6HCl2O4−, there are three crystallographically independent 1,2-diazinium cations and hydrogen chloranilate anions.
Kazuma Gotoh, Hiroyuki Ishida
doaj +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Hydrogen-bonding patterns in 5-fluorocytosine–melamine co-crystal (4/1)
Acta Crystallographica Section E: Crystallographic Communications, 2016 The asymmetric unit of the title compound, 4C4H4FN3O·C3H6N6, comprises of two independent 5-fluorocytosine (5FC) molecules (A and B) and one half-molecule of melamine (M). The other half of the melamine molecule is generated by a twofold axis.
Marimuthu Mohana +3 more
doaj +1 more source