Results 271 to 280 of about 672,685 (308)

Metabolic Reprogramming Driven by Trophoblasts and Decidual XCR1+PMN‐MDSC Crosstalk Controls Adverse Outcomes Associated With Advanced Maternal Age

Advanced Science, EarlyView.
The interaction between trophoblasts and decidual polymorphonuclear myeloid‐derived suppressor cells (dPMN‐MDSCs) via the XCL1–XCR1 axis is crucial for fetal development during the third trimester. Disruption of this axis impairs FOXO1 activity and causes metabolic imbalance in dPMN‐MDSCs, contributing to adverse outcomes associated with advanced ...
Meiqi Chen, Yuxiong Guo, Qing Zhao, Jingping Liu, Shuyi Kuang, Zhengcong Huang, Chenlin Lv, Shuxiu Xu, Zekai Zhuang, Anyan Yang, Jing Li, Kai Wu, Yumei He   +12 more
wiley   +1 more source

CXCL9 and CXCL10 Induce Expression of Nociceptive Ion Channels in Primary Sensory Neurons in Models of HIV-Associated Distal Sensory Polyneuropathy. [PDF]

Int J Mol Sci
Warfield R, Robinson JA, Baak S, Podgorski RM, Gabor TA, Caocci M, Niu M, Miller AD, Fox HS, Burdo TH.   +9 more
europepmc   +1 more source

The Role of Neuroinflammation in the Pathogenesis of Hepatic Encephalopathy. [PDF]

J Immunol Res
Rhodes K, Wang Y, DeMorrow S, Gurumallesh P.   +3 more
europepmc   +1 more source

Osteoarthritis Bone Marrow MSCs Retain Regenerative Competence and Chemokine Responsiveness for Drug-Based In Situ Tissue Engineering. [PDF]

Stem Cells Int
Sonnleitner J, Gulich K, Pruss A, Perka C, Gursche A, Kendoff D, Sittinger M, Hemmati-Sadeghi S, Dehne T.   +8 more
europepmc   +1 more source

Thykamine™: A New Player in the Field of Anti-Inflammatory Drugs. [PDF]

Biomedicines
Lynde C, Flamand L, McCarty V, Sampalis J.   +3 more
europepmc   +1 more source

Beyond neuronal loss: epigenetic signatures bridging immune activation and sleep dysfunction in narcolepsy type 1. [PDF]

Sleep
BaHammam AS.
europepmc   +1 more source

C-C Chemokine Receptor Type 5 regulates the levels of vasculitis and vascular dysfunction in a murine model Kawasaki Disease via adjusting the IL-6 formation

Physiology, 2023
Introduction: Kawasaki disease (KD) is a form of vasculitis characterized inflammation of the blood vessels. It is the most common cause of acquired cardiovascular disease in children and its etiology is unknown. The chemokine C-C motif receptor 5 (CCR5) is broadly studied in infectious diseases and its polymorphism can influence the KD susceptibility
Juliano Alves, Rafael Costa, Wanessa Awata, Shubhnita Singh, Ariane Bruder-Nascimento, Gabriela Barbosa, Thiago Bruder-Nascimento   +6 more
semanticscholar   +3 more sources

Early Process Development of PF-07054894, a Squaramide-Based Antagonist of C–C Chemokine Receptor Type 6 (CCR6)

Organic Process Research & Development
Gary M. Chinigo, Emma L. McInturff, Scott W. Bagley, Richard W. Barnhart, David C. Blakemore, Lu Han, Taegyo Lee, Javier Magano, J. Christopher McWilliams, Sebastien Monfette, James J. Mousseau, Senliang Pan, Dylan Pedro, Hahdi H. Perfect, Jeffrey W. Raggon, Peter R. Rose, John Sagal, John I. Trujillo, Jared Van Haitsma, Michael G. Vetelino, Xiaojing Helen Yang   +20 more
semanticscholar   +3 more sources