Results 201 to 210 of about 459,122 (273)

Targeting the Menin–KMT2A interaction in leukemia: Lessons learned and future directions

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Chromosomal rearrangements involving the Mixed Lineage Leukemia gene (MLL1, KMT2A) are defining a genetically distinct subset in about 10% of human acute leukemias. Translocations involving the KMT2A‐locus at chromosome 11q23 are resulting in the formation of a chimeric oncogene, where the N‐terminal part of KMT2A is fused to a variety of ...
Florian Perner   +3 more
wiley   +1 more source

QSCNAS: A platform for quorum sensing and quenching bacteria analysis in global wastewater treatment plants

open access: yesiMeta, EarlyView.
This study identifies the potential quorum sensing (QS) bacteria in wastewater treatment plants (WWTPs) and constructs a QS communication network through the establishment of a local QS bacterial database with six languages and the analysis of over 1000 activated sludge microbiome samples collected from 269 WWTPs.
Yong‐Chao Wang   +3 more
wiley   +1 more source

How c-di-GMP controls progression through the Streptomyces life cycle. [PDF]

open access: yesCurr Opin Microbiol
Gallagher KA   +4 more
europepmc   +1 more source

Integrative cross‐tissue analysis unveils complement‐immunoglobulin augmentation and dysbiosis‐related fatty acid metabolic remodeling during mammalian aging

open access: yesiMeta, EarlyView.
Our study provides a comprehensive multi‐omics profile of aging, integrating proteomic, metabolomic, and metagenomic analyses across diverse tissues and plasma. We identified the synergistic amplification of the circulating complement system and tissue‐wide immunoglobulin accumulation as key molecular drivers of inflammaging.
Feng Zhang   +17 more
wiley   +1 more source

Author Correction: A c-di-GMP signaling module controls responses to iron in Pseudomonas aeruginosa. [PDF]

open access: yesNat Commun
Zhan X   +8 more
europepmc   +1 more source

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