Results 201 to 210 of about 470,032 (357)
Novel c-di-GMP recognition modes of the mouse innate immune adaptor protein STING. Corrigendum [PDF]
, 2013 Ko‐Hsin Chin +10 more
openalex +1 more source
Investigation of the biosynthesis of exopolysaccharides within the biofilm matrix of Pseudomonas aeruginosa and Pseudomonas syringae pv. actinidiea : a thesis presented in partial fulfilment of the requirements for degree of Doctor of Philosophy in Microbiology and Genetics at Massey University, Manawatu, New Zealand [PDF]
, 2017 Polysaccharides are highly abundant natural biopolymers, which have biologically significant structural functions in living organisms. Various polysaccharides, with specific physicochemical properties, contribute to biofilm formation; defined as cell ...
Ghods, Shirin
core
Advanced Science, EarlyView.This review first summarizes the complex pathogenesis of atherosclerosis and outlines the limitations of conventional therapies. It then explores innovative nanoparticle drug delivery system (NDDS) developments, detailing their precision targeting strategies, responsiveness to plaque‐specific stimuli, modulation of key pathological processes, and ...
Yunqi Zhang +13 more
wiley +1 more source
Polyphosphate, cyclic AMP, guanosine tetraphosphate, and c-di-GMP reduce in vitro Lon activity [PDF]
, 2014 Devon O. Osbourne +3 more
openalex +1 more source
Advanced Science, EarlyView.Shear‐activated nanoparticles carrying nitroglycerin selectively target high‐shear stress collateral vessels during ischaemic stroke, enhancing blood flow to at‐risk brain without systemic side effects. This novel approach significantly improves outcomes in animal models, outperforming conventional nitroglycerin delivery.
Magdalena Litman +21 more
wiley +1 more source
A Network‐Driven Framework for Drug Response Precision Prediction of Acute Myeloid Leukemia
Advanced Science, EarlyView.A network‐based precision medicine platform, named NetAML is offered for personalized treatment of AML. It combines network analysis and machine learning to develop 87 models predicting drug sensitivity for clinical drugs. NetAML identifies interpretable gene signatures that drive differential drug responses, enabling the prediction of individual ...
Yinyin Wang +7 more
wiley +1 more source
Advanced Science, EarlyView.This review explores the transformative potential of lipid‐based nanoparticles (LNPs) in renal cell carcinoma (RCC) therapy. It systematically analyzes six LNP platforms‐from liposomes to hybrid nanoparticles‐highlighting their unique advantages in targeted drug delivery, resistance reversal, and immunomodulation.
Wei Yao +7 more
wiley +1 more source
Estudo de proteínas GGDEF-EAL em vias de sinalização de c-di-GMP em Xanthomonas citri subsp. citri [PDF]
, 2015 Raphael Dias Teixeira
openalex +1 more source
Advanced Science, EarlyView.CDSCs exhibit the potential to differentiate into endothelial cells, vascular pericytes, and osteoblasts. These differentiated cells are capable of secreting additional pro‐hematopoietic cytokines. Furthermore, CDSCs can inhibit apoptosis and reduce DNA damage in injured hematopoietic stem and progenitor cells (HSPCs, including RHSCs and RHPCs), while ...
Rui Dong +16 more
wiley +1 more source