Results 201 to 210 of about 459,122 (273)
Targeting the Menin–KMT2A interaction in leukemia: Lessons learned and future directions
Abstract Chromosomal rearrangements involving the Mixed Lineage Leukemia gene (MLL1, KMT2A) are defining a genetically distinct subset in about 10% of human acute leukemias. Translocations involving the KMT2A‐locus at chromosome 11q23 are resulting in the formation of a chimeric oncogene, where the N‐terminal part of KMT2A is fused to a variety of ...
Florian Perner+3 more
wiley +1 more source
c-di-GMP phosphodiesterase ProE interacts with quorum sensing protein PqsE to promote pyocyanin production in <i>Pseudomonas aeruginosa</i>. [PDF]
Feng Q+5 more
europepmc +1 more source
Intact and mutated Shigella diguanylate cyclases increase c-di-GMP. [PDF]
Ojha R, Krug S, Jones P, Koestler BJ.
europepmc +1 more source
This study identifies the potential quorum sensing (QS) bacteria in wastewater treatment plants (WWTPs) and constructs a QS communication network through the establishment of a local QS bacterial database with six languages and the analysis of over 1000 activated sludge microbiome samples collected from 269 WWTPs.
Yong‐Chao Wang+3 more
wiley +1 more source
How c-di-GMP controls progression through the Streptomyces life cycle. [PDF]
Gallagher KA+4 more
europepmc +1 more source
Our study provides a comprehensive multi‐omics profile of aging, integrating proteomic, metabolomic, and metagenomic analyses across diverse tissues and plasma. We identified the synergistic amplification of the circulating complement system and tissue‐wide immunoglobulin accumulation as key molecular drivers of inflammaging.
Feng Zhang+17 more
wiley +1 more source
Author Correction: A c-di-GMP signaling module controls responses to iron in Pseudomonas aeruginosa. [PDF]
Zhan X+8 more
europepmc +1 more source