Results 201 to 210 of about 24,065 (296)

Lymphocyte Micronucleus Formation Is Driven by Inflammation‐Induced Oxidative DNA Damage in Oesophageal Cancer Development

International Journal of Cancer, EarlyView.
Chromosomal instability is a hallmark of cancer, but minimally invasive ways to detect systemic DNA damage and cancer risk remain limited. Here, using patient blood samples, the authors investigated lymphocyte micronuclei (MN) frequency as a potential marker of DNA damage across the progression from gastroesophageal reflux disease to Barrett's ...
Kathryn Munn, Rachel Lawrence, Hasan Haboubi, Hamsa Naser, Kate Hurlow, Ume‐Kulsoom Shah, Lisa Williams, Sarah Gwynne, Owen Bodger, Jiri Zavadil, Francois Virard, Shareen Doak, Laura E. Thomas, Gareth Jenkins   +13 more
wiley   +1 more source

Ampicillin promotes the biofilm formation of <i>Shewanella putrefaciens</i> through the c-di-GMP-regulated BpfAGD system. [PDF]

Microbiol Spectr
Shi R, Sun D, Liu J, Yang J, Zhu J, Liu C, Liu W.   +6 more
europepmc   +1 more source

Tumor Infiltrating Lymphocyte Therapy Combined With PD‐1/LAG‐3 Inhibition in Patients With Recurrent Platinum‐Resistant Ovarian Cancer

International Journal of Cancer, EarlyView.
The detection of tumor‐infiltrating lymphocytes (TILs) is a positive prognostic factor in ovarian cancer. Moreover, TILs are significantly boosted by immunotherapy, though ovarian cancer patients have seen limited benefit from immune therapies. This study investigated the safety and feasibility of TIL therapy combined with PD‐1 and LAG‐3 inhibitors in ...
Tine J. Monberg, Cathrine L. Lorentzen, Marie C. W. Westergaard, Trine Z. Iversen, Troels H. Borch, Marco Donia, Sigrid M. Mannering, Stine E. W. Banke, Özcan Met, Inge Marie Svane   +9 more
wiley   +1 more source

The rising tide: Trends in induction of labor at term over a 5‐year period at a single centre

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 383-390, April 2025.
Abstract Objective Induction of labor (IOL) is a controversial topic in contemporary obstetric practice, with some suggesting that the increase in elective induction (eIOL) as a potential contributor to increasing cesarean delivery (CD) rates. The objectives of this single‐center study were to examine the rates of IOL, trends in indications for IOL ...
Sarah M. Nicholson, Susan Hatt, Etaoin M. Kent, Michael P. Geary, Patrick Dicker, Zara E. Molphy, Karen Flood, Fergal D. Malone   +7 more
wiley   +1 more source

Parallel regulatory circuits orchestrate biofilm formation in response to c-di-GMP levels and growth phase. [PDF]

PLoS Genet
Trebino MA, Kitts G, Haycocks JRJ, Wheat R, Chaudry I, Park JH, Erill I, Grainger DC, Yildiz FH.   +8 more
europepmc   +1 more source

Predictive factors for emergency cesarean section in grand multiparous compared to primiparous and multiparous women

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To identify predictive factors for emergency cesarean section (CS) in grand multiparous women and compare them with primiparous and multiparous women. Methods This was a retrospective cohort study in a single large university‐affiliated tertiary medical center between 2011 and 2018, analyzing all women with singleton pregnancies that
Roza Berkovitz Shperling, Liat Lerner‐Geva, Gal Ariel, Inna Zaslavsky Paltiel, Vered H. Eisenberg   +4 more
wiley   +1 more source

PelD is required downstream of c-di-GMP for host specialization of Pseudomonas lurida. [PDF]

BMC Microbiol
Czerwinski A, Löwenstrom J, Franzenburg S, Groth EE, Obeng N, Schulenburg H.   +5 more
europepmc   +1 more source

Engineered extracellular vesicles for precision renal therapy: Bioengineering strategies and clinical translation

Interdisciplinary Medicine, EarlyView.
Engineered extracellular vesicles (EVs) offer a versatile platform for kidney‐targeted therapy. This review summarizes bioengineering strategies, including cargo loading, surface modification, biomimetic fabrication, and biomaterial integration. We highlight translational challenges and propose future solutions to accelerate the clinical application of
Linru Shi, Bei Li, Wanzhu Liu, Haifeng Wu, Wenrong Xu, Cheng Ji, Hui Qian   +6 more
wiley   +1 more source

Reply to: "c-di-GMP does not bind H-NS, nor inhibits H-NS binding DNA". [PDF]

Nat Commun
Li S, Zhang L.
europepmc   +1 more source

Engineering exosomal cargo loading via endogenous molecular pathways: Strategies to enhance therapeutic potential

Interdisciplinary Medicine, EarlyView.
This review illustrates how scientists engineer exosomes by hijacking the cell's own cargo‐sorting machinery. These strategies efficiently load therapeutic molecules into natural vesicles, creating powerful next‐generation drug delivery systems (Created with BioGDP.com).
Huanrong Zhu, Chenning Zhang, Shihan Ma, Zhanxue Xu, Cailing Liang, Fang Cheng, Hongbo Chen   +6 more
wiley   +1 more source