Results 1 to 10 of about 220 (87)
Frontiers in Microbiology, 2023 Pectobacterium carotovorum is an important plant pathogen responsible for the destruction of crops through bacterial soft rot, which is modulated by oxygen (O2) concentration. A soluble globin coupled sensor protein, Pcc DgcO (also referred to as PccGCS)
Florian J. Fekete +4 more
doaj +3 more sources
Studying GGDEF Domain in the Act: Minimize Conformational Frustration to Prevent Artefacts
Life, 2021 GGDEF-containing proteins respond to different environmental cues to finely modulate cyclic diguanylate (c-di-GMP) levels in time and space, making the allosteric control a distinctive trait of the corresponding proteins.
Federico Mantoni +10 more
doaj +1 more source
Scientific Reports, 2023 Bordetella bronchiseptica is a gram-negative bacterium that causes respiratory diseases in different animals, including mice, making B. bronchiseptica the gold-standard model to investigate host–pathogen interaction at the molecular level.
Keila Belhart +3 more
doaj +1 more source
Identification of flgZ as a flagellar gene encoding a PilZ domain protein that regulates swimming motility and biofilm formation in Pseudomonas. [PDF]
PLoS ONE, 2014 Diguanylate cyclase and phosphodiesterase enzymatic activities control c-di-GMP levels modulating planktonic versus sessile lifestyle behavior in bacteria.
Francisco Martínez-Granero +8 more
doaj +1 more source
GGDEF domain as spatial on-switch for a phosphodiesterase by interaction with landmark protein HubP
npj Biofilms and Microbiomes, 2022 In bacteria, the monopolar localization of enzymes and protein complexes can result in a bimodal distribution of enzyme activity between the dividing cells and heterogeneity of cellular behaviors.
Tim Rick +12 more
doaj +1 more source
Bacteriophage‐mediated interference of the c‐di‐GMP signalling pathway in Pseudomonas aeruginosa
Microbial Biotechnology, 2021 Summary C‐di‐GMP is a key signalling molecule which impacts bacterial motility and biofilm formation and is formed by the condensation of two GTP molecules by a diguanylate cyclase.
Jeroen De Smet +7 more
doaj +1 more source
mBio, 2021 The marine bacterium Vibrio fischeri colonizes its host, the Hawaiian bobtail squid, in a manner requiring both bacterial biofilm formation and motility. The decision to switch between sessile and motile states is often triggered by environmental signals
Alice H. Tischler +3 more
doaj +1 more source
Microorganisms, 2023 Expression of rdar (red, dry, and rough) colony morphology-based biofilm formation in Escherichia coli is highly variable. To investigate the molecular mechanisms of semi-constitutive rdar morphotype formation, we compared their cyclic di-GMP turnover ...
Annika Cimdins-Ahne +4 more
doaj +1 more source
The importance of conserved amino acids in heme-based globin-coupled diguanylate cyclases.
PLoS ONE, 2017 Globin-coupled diguanylate cyclases contain globin, middle, and diguanylate cyclase domains that sense O2 to synthesize c-di-GMP and regulate bacterial motility, biofilm formation, and virulence.
Xuehua Wan +4 more
doaj +1 more source
mBio, 2013 WspR is a hybrid response regulator-diguanylate cyclase that is phosphorylated by the Wsp signal transduction complex in response to growth of Pseudomonas aeruginosa on surfaces.
Varisa Huangyutitham +2 more
doaj +1 more source