Results 41 to 50 of about 40,793 (179)

Activation and polar sequestration of PopA, a c-di-GMP effector protein involved in Caulobacter crescentus cell cycle control [PDF]

, 2014
When Caulobacter crescentus enters S-phase the replication initiation inhibitor CtrA dynamically positions to the old cell pole to be degraded by the polar ClpXP protease.
Ebbensgaard, Anna Elisabeth, Ozaki, Shogo, Ebbensgaard, Anna, Schirmer, Tilman, Zumthor, Ludwig, Manfredi, Pablo, Jenal, Urs, Schalch-Moser, Annina, Ozaki S, Zumthor L, Schirmer T, Ebbensgaard A, Jenal U, Manfredi P, Schalch-Moser A   +14 more
core   +1 more source

Subcellular Clustering of the Phosphorylated WspR Response Regulator Protein Stimulates Its Diguanylate Cyclase Activity

mBio, 2013
WspR is a hybrid response regulator-diguanylate cyclase that is phosphorylated by the Wsp signal transduction complex in response to growth of Pseudomonas aeruginosa on surfaces.
Varisa Huangyutitham, Zehra Tüzün Güvener, Caroline S. Harwood   +2 more
doaj   +1 more source

Bacterial cyclic diguanylate signaling networks sense temperature [PDF]

, 2021
Many bacteria use the second messenger cyclic diguanylate (c-di-GMP) to control motility, biofilm production and virulence. Here, we identify a thermosensory diguanylate cyclase (TdcA) that modulates temperature-dependent motility, biofilm development ...
Singh, Manu, Nicolas Fournier, Julie Groizeleau, Justin L. MacCallum, Joe Jonathan Harrison, Jennings, Laura K., Good, Nathan M., Ian A. Lewis, Weerayuth Kittichotirat, Singletary, Larissa A., Ann Karen Cornelia Brassinga, Ayush Kumar, MacCallum, Justin L., Lou, Yuefei, Maria Silvina Stietz, Rich, Jacquelyn D., Bryan G. Yipp, Stietz, Maria Silvina, Bumgarner, Roger E., Hynes, Michael F., Trevor E. Randall, Fournier, Nicolas, Kumar, Ayush, Elise Granton, Groves, Ryan A., Yipp, Bryan G., Randall, Trevor E., Katherine Leblanc, Fanny Liu, Kittichotirat, Weerayuth, Boo Shan Tseng, Parsek, Matthew R., Jacquelyn D. Rich, Roger E. Bumgarner, Fiona S. L. Brinkman, Brinkman, Fiona S.L., Tseng, Boo Shan, Yuefei Lou, Laura K. Jennings, Emily Au, Winsor, Geoffrey L., Matthew R. Parsek, Au, Emily, Almblad, Henrik, Nathan M. Good, Larissa A. Singletary, Groizeleau, Julie, Henrik Almblad, Michael F. Hynes, Manu Singh, Harrison, Joe Jonathan, Liu, Fanny, Brassinga, Ann Karen Cornelia, Leblanc, Katherine, Lewis, Ian A., Geoffrey L. Winsor, Granton, Elise, Tara M. L. Winstone, Winstone, Tara M.L., Ryan A. Groves   +59 more
core   +1 more source

A novel c-di-GMP signal system regulates biofilm formation in Pseudomonas aeruginosa

Microbial Cell, 2020
The bacterial second messenger cyclic-di-GMP (c-di-GMP) controls biofilm formation and other phenotypes relevant to pathogenesis. The human pathogen Pseudomonas aeruginosa encodes 17 diguanylate cyclase (DGCs) proteins which are required for c-di-GMP ...
Gukui Chen, Haihua Liang
doaj   +1 more source

Structural elucidation of the multidomain response regulator PleD using X-ray crystallography [PDF]

, 2004
c-diGMP (bis-(3!5)-cyclic di-guanosine monophosphate) is used extensively in bacteria to control biofilm formation and is lately postulated as a novel secondary messenger.
Chan, Carmen
core   +1 more source

Specialized and shared functions of diguanylate cyclases and phosphodiesterases in Streptomyces development [PDF]

Molecular Microbiology, 2020
Abstract Levels of the second messenger bis-3’-5’-cyclic di-guanosinemonophosphate (c-di-GMP) determine when Streptomyces initiate sporulation to survive under adverse conditions. c-di-GMP signals are integrated into the genetic differentiation network by the regulator BldD and the ...
Haist, Julian, Neumann, Sara Alina, Al-Bassam, Mahmoud M, Lindenberg, Sandra, Elliot, Marie A, Tschowri, Natalia   +5 more
openaire   +2 more sources

Investigating the allosteric regulation of YfiN from Pseudomonas aeruginosa: clues from the structure of the catalytic domain. [PDF]

PLoS ONE, 2013
Pseudomonas aeruginosa is responsible for a plethora of biofilm mediated chronic infections among which cystic fibrosis pneumonia is the most frightening. The long-term survival strategy of P.
Giorgio Giardina, Alessandro Paiardini, Silvia Fernicola, Stefano Franceschini, Serena Rinaldo, Valentina Stelitano, Francesca Cutruzzolà   +6 more
doaj   +1 more source

Cyanobacteriochrome SesA Is a Diguanylate Cyclase That Induces Cell Aggregation in Thermosynechococcus [PDF]

Journal of Biological Chemistry, 2014
Cyanobacteria have unique photoreceptors, cyanobacteriochromes, that show diverse spectral properties to sense near-UV/visible lights. Certain cyanobacteriochromes have been shown to regulate cellular phototaxis or chromatic acclimation of photosynthetic pigments.
Gen, Enomoto, Ryouhei, Nomura, Takashi, Shimada, , Ni-Ni-Win, Rei, Narikawa, Masahiko, Ikeuchi   +5 more
openaire   +2 more sources

c-di-GMP-related phenotypes are modulated by the interaction between a diguanylate cyclase and a polar hub protein. [PDF]

Sci Rep, 2020
c-di-GMP is a major player in the switch between bioflm and motile lifestyles. Several bacteria exhibit a large number of c-di-GMP metabolizing proteins, thus a fne-tuning of this nucleotide levels may occur.
Nicastro GG, Kaihami GH, Pulschen AA, Hernandez-Montelongo J, Boechat AL, de Oliveira Pereira T, Rosa CGT, Stefanello E, Colepicolo P, Bordi C, Baldini RL.   +10 more
europepmc   +3 more sources

Diguanylate cyclase DgcP is involved in plant and human Pseudomonas spp. infections [PDF]

, 2015
The second messenger cyclic di-GMP (c-di-GMP) controls the transition between different lifestyles in bacterial pathogens. Here, we report the identification of DgcP (diguanylate cyclase conserved in Pseudomonads), whose activity in the olive tree ...
Aragon, IM, Moscoso, JA, Gallegos, M-T, Ramos, C, Guery, B, Filloux, A, Pérez-Mendoza, D, Faure, E, Aragón, Isabel M., Guery, B., Faure, E., Pérez-Mendoza, Daniel, Moscoso, J.A., Gallegos, María Trinidad, Ramos, Cayo, Filloux, Alain   +15 more
core   +2 more sources