Results 51 to 60 of about 35,352 (121)

Responsive nitric oxide‐releasing antibacterial materials for biofilm‐associated infections: Mechanisms, design strategies, and applications

open access: yesResponsive Materials, Volume 4, Issue 3, August 2026.
This review summarizes the recent progress in responsive NO‐releasing materials and their applications in biofilm‐associated infectious diseases. The design principles and response mechanisms are given to provide inspiration toward the future development of multi‐responsive NO‐releasing materials.
Wenyue Sun   +8 more
wiley   +1 more source

Diguanylate cyclase DgcP is involved in plant and human Pseudomonas spp. infections [PDF]

open access: yes, 2015
The second messenger cyclic di-GMP (c-di-GMP) controls the transition between different lifestyles in bacterial pathogens. Here, we report the identification of DgcP (diguanylate cyclase conserved in Pseudomonads), whose activity in the olive tree ...
Aragon, IM   +7 more
core   +2 more sources

Regulation of Protein Secretion Systems Mediated by Cyclic Diguanylate in Plant-Interacting Bacteria

open access: yesFrontiers in Microbiology, 2019
The ubiquitous second messenger cyclic diguanylate (c-di-GMP) is involved in the regulation of different processes in bacteria. In phytopathogens, intracellular fluctuations in the concentration of this molecule contribute to the lifestyle switching from
Francisco Javier López-Baena   +2 more
doaj   +1 more source

Recent Advances in the Molecular Mechanisms of Bacterial Anti‐Phage Defence Systems

open access: yesMicrobial Biotechnology, Volume 19, Issue 8, August 2026.
Panoptes as an example for an antiphage system consists of OptS producing a cyclic dinucleotide that prevents activation of OptE, a transmembrane protein. Phage T4 infection introduces the sponge protein Acb2 that adsorbs the cyclic dinucleotide thus activating OptE which disrupts the cell membrane aborting phage infection.
Harald Brüssow
wiley   +1 more source

Population Genomics of Microbial Biostalactites: Non-recombinogenic Genome Islands and Microdiversification by Transposons

open access: yesFrontiers in Microbiology, 2022
Intrapopulation genetic variability in prokaryotes is receiving increasing attention thanks to improving sequencing methods; however, the ability to distinguish intrapopulation variability from species clusters or initial stages of gene flow barrier ...
Kateřina Burkartová   +4 more
doaj   +1 more source

TolC Is Required for a Mixed‐Linkage β‐Glucan (MLG) Biosynthesis: Engineering Bacteria for MLG Overproduction

open access: yesMicrobial Biotechnology, Volume 19, Issue 8, August 2026.
TolC is identified as an essential component of the mixed‐linkage β‐glucan (MLG) biosynthetic machinery in Sinorhizobium meliloti, likely enabling polymer export. Co‐expression of tolC, bgsBA, and pleD* significantly enhances MLG production and enables its synthesis in non‐native bacterial hosts.
L. Ruiz‐Sáez   +6 more
wiley   +1 more source

Activation of the diguanylate cyclase PleD by phosphorylation-mediated dimerization

open access: yes, 2007
Diguanylate cyclases (DGCs) are key enzymes of second messenger signaling in bacteria. Their activity is responsible for the condensation of two GTP molecules into the signaling compound cyclic di-GMP.
Abel, Sören   +11 more
core   +1 more source

ASSESSMENT OF A PREDICTED DIGUANYLATE CYCLASE IN TREPONEMA DENTICOLA [PDF]

open access: yes, 2018
Periodontal disease is a progressive inflammatory condition that is characterized by the reabsorption of alveolar bone, the destruction of connective tissue, and edentulism. It is caused by a dysbiosis in the oral microbiome as a result of a shift from a
Patel, Dhara T
core   +1 more source

c-di-GMP-related phenotypes are modulated by the interaction between a diguanylate cyclase and a polar hub protein [PDF]

open access: yes, 2020
c-di-GMP is a major player in the switch between bioflm and motile lifestyles. Several bacteria exhibit a large number of c-di-GMP metabolizing proteins, thus a fne-tuning of this nucleotide levels may occur.
Stefanello, E   +10 more
core   +2 more sources

Comparative analysis of diguanylate cyclase and phosphodiesterase genes in Klebsiella pneumoniae

open access: yesBMC Microbiology, 2012
Background Klebsiella pneumoniae can be found in environmental habitats as well as in hospital settings where it is commonly associated with nosocomial infections.
Cruz Diana P   +4 more
doaj   +1 more source

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