Results 1 to 10 of about 3,106 (185)

In silico comparative analysis of GGDEF and EAL domain signaling proteins from the Azospirillum genomes [PDF]

BMC Microbiology, 2018
Background The cyclic-di-GMP (c-di-GMP) second messenger exemplifies a signaling system that regulates many bacterial behaviors of key importance; among them, c-di-GMP controls the transition between motile and sessile life-styles in bacteria. Cellular c-
Alberto Ramírez Mata, César Millán Pacheco, José F. Cruz Pérez, Martha Minjárez Sáenz, Beatriz E. Baca   +4 more
doaj   +3 more sources

c-di-GMP turn-over in Clostridium difficile is controlled by a plethora of diguanylate cyclases and phosphodiesterases. [PDF]

PLoS Genetics, 2011
Clostridium difficile infections have become a major healthcare concern in the last decade during which the emergence of new strains has underscored this bacterium's capacity to cause persistent epidemics.
Eric Bordeleau, Louis-Charles Fortier, François Malouin, Vincent Burrus   +3 more
doaj   +1 more source

Control of Cell Size by c-di-GMP Requires a Two-Component Signaling System in the Cyanobacterium Anabaena sp. Strain PCC 7120

Microbiology Spectrum, 2023
Each bacterial species possesses a specific cell size and morphology, which constitute important and recognizable physical traits. How bacteria maintain their particular cell size and morphology remains an essential question in microbiology ...
Qin-Xue Sun, Min Huang, Ju-Yuan Zhang, Xiaoli Zeng, Cheng-Cai Zhang   +4 more
doaj   +1 more source

Diguanylate Cyclases in Vibrio cholerae: Essential Regulators of Lifestyle Switching

Frontiers in Cellular and Infection Microbiology, 2020
Biofilm formation in Vibrio cholerae empowers the bacteria to lead a dual lifestyle and enhances its infectivity. While the formation and dispersal of the biofilm involves multiple components—both proteinaceous and non-proteinaceous, the key to the ...
Sumit Biswas, Om Prakash Chouhan, Divya Bandekar   +2 more
doaj   +1 more source

Characterisation of Variants of Cyclic di-GMP Turnover Proteins Associated with Semi-Constitutive rdar Morphotype Expression in Commensal and Uropathogenic Escherichia coli Strains

Microorganisms, 2023
Expression of rdar (red, dry, and rough) colony morphology-based biofilm formation in Escherichia coli is highly variable. To investigate the molecular mechanisms of semi-constitutive rdar morphotype formation, we compared their cyclic di-GMP turnover ...
Annika Cimdins-Ahne, Ali-Oddin Naemi, Fengyang Li, Roger Simm, Ute Römling   +4 more
doaj   +1 more source

Identification of the core c-di-GMP turnover proteins responsible for root colonization of Bacillus velezensis

iScience, 2022
Summary: Root colonization by beneficial rhizobacteria determines their plant beneficial effects. The messenger c-di-GMP is involved in the bacterial transition process between motility and biofilm, which are crucial to the colonization ability of the ...
Xiaoyan Dong, Chen Tu, Yanan Liu, Ruifu Zhang, Yunpeng Liu   +4 more
doaj   +1 more source

The Structure of an Unconventional HD-GYP Protein from Bdellovibrio Reveals the Roles of Conserved Residues in this Class of Cyclic-di-GMP Phosphodiesterases

mBio, 2011
Cyclic-di-GMP is a near-ubiquitous bacterial second messenger that is important in localized signal transmission during the control of various processes, including virulence and switching between planktonic and biofilm-based lifestyles.
Andrew L. Lovering, Michael J. Capeness, Carey Lambert, Laura Hobley, R. Elizabeth Sockett   +4 more
doaj   +1 more source

Genetic dissection of Escherichia coli's master diguanylate cyclase DgcE: Role of the N-terminal MASE1 domain and direct signal input from a GTPase partner system.

PLoS Genetics, 2019
The ubiquitous second messenger c-di-GMP promotes bacterial biofilm formation by playing diverse roles in the underlying regulatory networks. This is reflected in the multiplicity of diguanylate cyclases (DGC) and phosphodiesterases (PDE) that synthesize
Vanessa Pfiffer, Olga Sarenko, Alexandra Possling, Regine Hengge   +3 more
doaj   +1 more source

Characterization and analysis of a novel diguanylate cyclase PA0847 from Pseudomonas aeruginosa PAO1

Infection and Drug Resistance, 2019
Yan Zhang,1,2 Jiayi Guo,1 Ning Zhang,2 Wensu Yuan,2 Zhi Lin,2 Weidong Huang11Department of Biochemistry and Molecular Biology, School of Basic Medicine, Ningxia Medical University, Yinchuan 750004, People’s Republic of China; 2School of Life ...
Zhang Y, Guo J, Zhang N, Yuan W, Lin Z, Huang W   +5 more
doaj  

A GGDEF and EAL domain-containing protein in Pseudomonas syringae pv. actinidiae regulates virulence via its diguanylate cyclase activity

Phytopathology Research
Kiwifruit bacterial canker (KBC), caused by Pseudomonas syringae pv. actinidiae (Psa), poses a severe threat to the global kiwifruit industry, highlighting the urgent need to elucidate its pathogenic mechanisms. Cyclic diguanylate monophosphate (c-di-GMP)
Yudi Wang, Mingming Yang, Jinfang Zhou, Xianwei Xie, Jiabing Ma, Yao Wang, Xihui Shen, Lili Huang   +7 more
doaj   +1 more source