Results 31 to 40 of about 4,652 (199)

Proteins with GGDEF and EAL domains regulatePseudomonas putidabiofilm formation and dispersal [PDF]

FEMS Microbiology Letters, 2006
Microbial biofilm formation often causes problems in medical and industrial settings, and knowledge about the factors that are involved in biofilm development and dispersion is useful for creating strategies to control the processes. In this report, we present evidence that proteins with GGDEF and EAL domains are involved in the regulation of biofilm ...
Morten, Gjermansen, Paula, Ragas, Tim, Tolker-Nielsen   +2 more
openaire   +2 more sources

The Degenerate EAL-GGDEF Domain Protein Filp Functions as a Cyclic di-GMP Receptor and Specifically Interacts with the PilZ-Domain Protein PXO_02715 to Regulate Virulence in Xanthomonas oryzae pv. oryzae

Molecular Plant-Microbe Interactions, 2014
Degenerate GGDEF and EAL domain proteins represent major types of cyclic diguanylic acid (c-di-GMP) receptors in pathogenic bacteria. Here, we characterized a FimX-like protein (Filp) which possesses both GGDEF and EAL domains in Xanthomonas oryzae pv ...
Fenghuan Yang, Fang Tian, Xiaotong Li, Susu Fan, Huamin Chen, Maosen Wu, Ching-Hong Yang, Chenyang He   +7 more
doaj   +1 more source

Characterization of the Xylella fastidiosa PD1671 gene encoding degenerate c-di-GMP GGDEF/EAL domains, and its role in the development of Pierce's disease. [PDF]

PLoS ONE, 2015
Xylella fastidiosa is an important phytopathogenic bacterium that causes many serious plant diseases including Pierce's disease of grapevines. X. fastidiosa is thought to induce disease by colonizing and clogging xylem vessels through the formation of ...
Luciana Cursino, Dusit Athinuwat, Kelly R Patel, Cheryl D Galvani, Paulo A Zaini, Yaxin Li, Leonardo De La Fuente, Harvey C Hoch, Thomas J Burr, Patricia Mowery   +9 more
doaj   +1 more source

A novel bacterial l-arginine sensor controlling c-di-GMP levels in Pseudomonas aeruginosa [PDF]

, 2018
Nutrients such as amino acids play key roles in shaping the metabolism of microorganisms in natural environments and in host–pathogen interactions.
Cutruzzolà, F., Giardina, G., Janson, G., Leoni, L., Mantoni, F., Paiardini, A., Paone, A., Rampioni, G., Rinaldo, S.   +8 more
core   +1 more source

A Zinc Lock on GGDEF Domain Dimerization Inhibits E. coli Biofilms [PDF]

Structure, 2013
In this issue of Structure, Zähringer and colleagues present crystal structures of an important signal transduction enzyme, diguanylate cyclase DgcZ from E. coli. The authors show that zinc ions bound to the CZB domain inhibit enzyme activity and reveal how zinc availability affects biofilm formation.
openaire   +2 more sources

The Conserved Actinobacterial Two-Component System MtrAB Coordinates Chloramphenicol Production with Sporulation in Streptomyces venezuelae NRRL B-65442 [PDF]

, 2017
Streptomyces bacteria make numerous secondary metabolites, including half of all known antibiotics. Production of antibiotics is usually coordinated with the onset of sporulation but the cross regulation of these processes is not fully understood.
Antoraz, Brocker, Bush, Bush, Capra, Clark, Crack, Devine, Fernández-Martínez, Forget, Friedland, Gregory, Gust, Hosaka, Hoskisson, Hsiao, Hutchings, Hutchings, Hutchings, Jeong, Katz, Kieser, Krämer, Liu, Munnoch, Möker, Nguyen, Nicol, Plocinska, Plocinska, Purushotham, Rodriguez, Rutledge, Salazar, Smith, Soding, Som, Zahrt, Zhang   +38 more
core   +9 more sources

New insights into Legionella pneumophila biofilm regulation by c-di-GMP signaling [PDF]

, 2016
The waterborne pathogen Legionella pneumophila grows as a biofilm, freely or inside amoebae. Cyclic-di-GMP (c-di-GMP), a bacterial second messenger frequently implicated in biofilm formation, is synthesized and degraded by diguanylate cyclases (DGCs) and
Allombert, Julie, Doublet, Patricia, Lajoie Halova, Barbora, Pécastaings, Sophie, Roques, Christine, Vianney, Anne   +5 more
core   +3 more sources

ScrG, a GGDEF-EAL Protein, Participates in Regulating Swarming and Sticking inVibrio parahaemolyticus [PDF]

Journal of Bacteriology, 2007
ABSTRACTIn this work, we describe a new gene controlling lateral flagellar gene expression. The gene encodes ScrG, a protein containing GGDEF and EAL domains. This is the second GGDEF-EAL-encoding locus determined to be involved in the regulation of swarming: the first was previously characterized and namedscrABC(for “swarming and capsular ...
Yun-Kyeong, Kim, Linda L, McCarter
openaire   +2 more sources

Cyclic-di-GMP signalling and biofilm-related properties of the Shiga toxin- producing 2011 German outbreak Escherichia coli O104:H4 [PDF]

, 2014
In 2011, nearly 4,000 people in Germany were infected by Shiga toxin (Stx)-producing Escherichia coli O104:H4 with > 22% of patients developing haemolytic uraemic syndrome (HUS).
Hengge, Regine, Povolotsky, Tatyana L., Richter, Anja M., Wieler, Lothar H.   +3 more
core   +1 more source

A Minimal Threshold of c-di-GMP Is Essential for Fruiting Body Formation and Sporulation in Myxococcus xanthus [PDF]

, 2016
Generally, the second messenger bis-(3’-5’)-cyclic dimeric GMP (c-di-GMP) regulates the switch between motile and sessile lifestyles in bacteria. Here, we show that c-di-GMP is an essential regulator of multicellular development in the social bacterium ...
A Duerig, A Konovalova, A Lu, AJ Schmidt, B Julien, BK Bharati, BY Chang, BY Matsuyama, BZ Harris, C Baraquet, C Spangler, CD Boyd, D Amikam, D Kaiser, D Skotnicka, D Srivastava, DA Ryjenkov, DA Ryjenkov, Dorota Skotnicka, E Bordeleau, E Trampari, Eleftheria Trampari, Gregory T. Smaldone, H Lancero, I Bulyha, I Letunic, IS Pultz, J Hodgkin, J Hodgkin, J Sambrook, Jacob G. Malone, Jennifer Liang, JJ Wilksch, Josep Casadesús, JP Massie, JT Pratt, JW Hickman, JW Hickman, KG Roelofs, KH Chin, L Hobley, L Jelsbak, L Søgaard-Andersen, LJ Shimkets, Lotte Søgaard-Andersen, M Christen, M Christen, M Fazli, M Merighi, M Overgaard, M Singer, Mitchell Singer, MR Neunuebel, MV Navarro, N Sudarsan, N Tschowri, NB Caberoy, PD Newell, PV Krasteva, PV Krasteva, R Hengge, R Paul, R Paul, R Tamayo, RP Ryan, RP Ryan, RP Ryan, S Abel, S Steiner, SS Wu, SS Wu, SS Wu, SZ Sultan, T Petters, T Schirmer, TA Ramelot, TM Gronewold, Tobias Petters, U Römling, V Jakovljevic, Volkhard Kaever, W Li, X Fang, Y Li, Y Qi, Z Yang, ZH Chen, ZM Yang   +87 more
core   +3 more sources