Results 41 to 50 of about 3,043 (159)

Identification, activity and disulfide connectivity of C-di-GMP regulating proteins in Mycobacterium tuberculosis. [PDF]

open access: yesPLoS ONE, 2010
C-di-GMP, a bacterial second messenger plays a key role in survival and adaptation of bacteria under different environmental conditions. The level of c-di-GMP is regulated by two opposing activities, namely diguanylate cyclase (DGC) and phosphodiesterase
Kajal Gupta   +2 more
doaj   +1 more source

TolC Is Required for a Mixed‐Linkage β‐Glucan (MLG) Biosynthesis: Engineering Bacteria for MLG Overproduction

open access: yesMicrobial Biotechnology, Volume 19, Issue 8, August 2026.
TolC is identified as an essential component of the mixed‐linkage β‐glucan (MLG) biosynthetic machinery in Sinorhizobium meliloti, likely enabling polymer export. Co‐expression of tolC, bgsBA, and pleD* significantly enhances MLG production and enables its synthesis in non‐native bacterial hosts.
L. Ruiz‐Sáez   +6 more
wiley   +1 more source

c-di-GMP turn-over in Clostridium difficile is controlled by a plethora of diguanylate cyclases and phosphodiesterases. [PDF]

open access: yesPLoS Genetics, 2011
Clostridium difficile infections have become a major healthcare concern in the last decade during which the emergence of new strains has underscored this bacterium's capacity to cause persistent epidemics.
Eric Bordeleau   +3 more
doaj   +1 more source

To Move or Not to Move: When and How Bacteria Suppress Flagellar Motility

open access: yesMolecular Microbiology, Volume 126, Issue 2, Page 173-189, August 2026.
Motility cessation in bacteria is a key regulatory strategy that provides multiple survival advantages including enhanced community cooperation, niche adaptation and evasion of host immune responses. This process is controlled by associated mechanisms such as post‐translational modifications and second messenger signalling that stabilise non‐motile ...
Fatemeh Mohaghegh   +2 more
wiley   +1 more source

Control of Cell Size by c-di-GMP Requires a Two-Component Signaling System in the Cyanobacterium Anabaena sp. Strain PCC 7120

open access: yesMicrobiology Spectrum, 2023
Each bacterial species possesses a specific cell size and morphology, which constitute important and recognizable physical traits. How bacteria maintain their particular cell size and morphology remains an essential question in microbiology ...
Qin-Xue Sun   +4 more
doaj   +1 more source

Pharmacological Evaluation of Methanolic Fruit Extract of Lannea coromandelica: Antioxidant, Cytotoxic, Antidiabetic, Antibacterial, Anti‐Inflammatory, and Sedative Activities

open access: yesFood Science &Nutrition, Volume 14, Issue 5, May 2026.
Phytochemical investigation of Lannea coromandelica through GC–MS and in silico analysis revealed diverse bioactive compounds with promising pharmacological potential. Integrated in vitro and in vivo assays demonstrated significant antioxidant, antidiabetic, antibacterial, anti‐inflammatory, and sedative activities, supporting its therapeutic relevance.
Priota Islam Meem   +7 more
wiley   +1 more source

GGDEF-EAL domain proteins in bacterial physiology

open access: yes, 2008
GGDEF and EAL domain proteins were identified in the chromosome of many bacteria. GGDEF domain proteins are generally diguanyl cyclases which synthesize the secondary messenger cyclic di-GMP.
Abdul Kader (33837)
core   +1 more source

In silico comparative analysis of GGDEF and EAL domain signaling proteins from the Azospirillum genomes

open access: yesBMC Microbiology, 2018
Background The cyclic-di-GMP (c-di-GMP) second messenger exemplifies a signaling system that regulates many bacterial behaviors of key importance; among them, c-di-GMP controls the transition between motile and sessile life-styles in bacteria. Cellular c-
Alberto Ramírez Mata   +4 more
doaj   +1 more source

The MarR Family Transcriptional Regulator EmrR Negatively Regulates the Type III Secretion System (T3SS) and Positively Modulates Pathogenicity in Dickeya oryzae

open access: yesMolecular Plant Pathology, Volume 27, Issue 4, April 2026.
This study revealed that the transcriptional regulator EmrR in Dickeya oryzae modulates virulence by regulating hrpL expression and c‐di‐GMP levels. It affects motility, biofilm formation, cellulase production and pathogenicity. EMSA and footprinting confirmed EmrR binds directly to the promoter of its target operon.
Mingfa Lv   +12 more
wiley   +1 more source

Diguanylate Cyclases in Vibrio cholerae: Essential Regulators of Lifestyle Switching

open access: yesFrontiers in Cellular and Infection Microbiology, 2020
Biofilm formation in Vibrio cholerae empowers the bacteria to lead a dual lifestyle and enhances its infectivity. While the formation and dispersal of the biofilm involves multiple components—both proteinaceous and non-proteinaceous, the key to the ...
Sumit Biswas   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy