Results 21 to 30 of about 2,948 (189)

Diguanylate Cyclase GdpX6 with c-di-GMP Binding Activity Involved in the Regulation of Virulence Expression in Xanthomonas oryzae pv. oryzae

Microorganisms, 2021
Cyclic diguanylate monophosphate (c-di-GMP) is a secondary messenger present in bacteria. The GGDEF-domain proteins can participate in the synthesis of c-di-GMP as diguanylate cyclase (DGC) or bind with c-di-GMP to function as a c-di-GMP receptor. In the
Weiwei Yan, Yiming Wei, Susu Fan, Chao Yu, Fang Tian, Qi Wang, Fenghuan Yang, Huamin Chen   +7 more
doaj   +1 more source

Comparative Genomic Analysis Identifies FleQ and GcbB as Virulence-Associated Factors in Pseudomonas syringae pv. tabaci Strains. [PDF]

Mol Plant Pathol
Comparative genomic analysis between highly virulent strain Pta6605 and less virulent strain Pta7375 showed that point mutations in fleQ and gcbB are responsible for the contrasting virulence‐related phenotypes between the two strains. ABSTRACT Pseudomonas syringae pv.
Hidayat MT, Yoshioka K, Nishimura T, Asai S, Masuda S, Shirasu K, Sakata N, Yamamoto M, Noutoshi Y, Toyoda K, Ichinose Y, Matsui H.   +11 more
europepmc   +2 more sources

Patterns of abundance, chromosomal localization, and domain organization among c-di-GMP-metabolizing genes revealed by comparative genomics of five alphaproteobacterial orders

BMC Genomics, 2022
Background Bis-(3′-5′)-cyclic dimeric guanosine monophosphate (c-di-GMP) is a bacterial second messenger that affects diverse processes in different bacteria, including the cell cycle, motility, and biofilm formation.
Sonja Koppenhöfer, Andrew S. Lang
doaj   +1 more source

Virulence Regulation and Lifestyle Transitions: The Role of c-di-GMP and Two-Component Systems in Erwinia amylovora and Their Evolutionary Context Within Enterobacterales. [PDF]

Mol Plant Pathol
Erwinia amylovora infects apple blossoms by activating the T3SS, then spreads systemically via amylovoran‐mediated biofilms. Transitions between motile and sessile states are regulated by key two‐component systems and c‐di‐GMP. This review summarises infection biology, virulence factors, regulatory networks and evolutionary insights underlying fire ...
Niroula D, Bhandari K, Sundin GW, Joshi JR.   +3 more
europepmc   +2 more sources

<i>Staphylococcus aureus</i> uses a GGDEF protein to recruit diacylglycerol kinase to the membrane for lipid recycling. [PDF]

Proc Natl Acad Sci U S A
Staphylococcus aureus is a Gram-positive pathogen responsible for numerous antibiotic-resistant infections. Identifying vulnerabilities in S. aureus is crucial for developing new antibiotics to treat these infections.
Mychack A, Evans D, Gilles T, James MJ, Walker S.   +4 more
europepmc   +4 more sources

Regulation of the physiology and virulence of Ralstonia solanacearum by the second messenger 2′,3′-cyclic guanosine monophosphate

Nature Communications, 2023
Previous studies have demonstrated that bis-(3',5')-cyclic diguanosine monophosphate (bis-3',5'-c-di-GMP) is a ubiquitous second messenger employed by bacteria. Here, we report that 2',3'-cyclic guanosine monophosphate (2',3'-cGMP) controls the important
Xia Li, Wenfang Yin, Junjie Desmond Lin, Yong Zhang, Quan Guo, Gerun Wang, Xiayu Chen, Binbin Cui, Mingfang Wang, Min Chen, Peng Li, Ya-Wen He, Wei Qian, Haibin Luo, Lian-Hui Zhang, Xue-Wei Liu, Shihao Song, Yinyue Deng   +17 more
doaj   +1 more source

Role of the GGDEF regulator PleD in polar development of Caulobacter crescentus [PDF]

Molecular Microbiology, 2003
SummarySeveral members of the two‐component signal transduction family have been implicated in the control of  polar development in Caulobacter crescentus: PleC and DivJ, two polarly localized histidine sensor kinases; and the response regulators DivK and PleD.
Aldridge, P., Paul, R., Goymer, P., Rainey, P., Jenal, U.   +4 more
openaire   +4 more sources

Role of the GGDEF protein family in Salmonella cellulose biosynthesis and biofilm formation [PDF]

Molecular Microbiology, 2004
Summary Salmonella enterica serovar Typhimurium is capable of producing cellulose as the main exopolysaccharide compound of the biofilm matrix. It has been shown for Gluconacetobacter xylinum that cellulose biosynthesis is allosterically regulated by bis‐(3′,5′) cyclic diguanylic acid, whose synthesis/degradation depends on diguanylate cyclase ...
García, Begoña, Latasa Osta, Cristina, Solano Goñi, Cristina, García del Portillo, Francisco, Gamazo de la Rasilla, Carlos, Lasa, Íñigo   +5 more
openaire   +3 more sources

CdgB GGDEF domain structure.

, 2022
(A) Sequence alignment between CdgB GGDEF domain from A. baldaniorum Sp245 (GenBank access number CCD03171.1) and other GGDEF domains of known structure. PleD, C. crescentus (GenBank access number YP_002517919.1), and RbdA, P.
Sandra R. Reyes-Carmona (14165033), Víctor I. Viruega-Góngora (14165027), Alberto Ramírez-Mata (6336152), María L. Xiqui-Vázquez (14165036), David Zamorano-Sánchez (8582430), Iris S. Acatitla-Jácome (14165030), Beatriz Eugenia Baca (6336146)   +6 more
core   +1 more source

ScrG, a GGDEF-EAL Protein, Participates in Regulating Swarming and Sticking inVibrio parahaemolyticus [PDF]

Journal of Bacteriology, 2007
ABSTRACTIn this work, we describe a new gene controlling lateral flagellar gene expression. The gene encodes ScrG, a protein containing GGDEF and EAL domains. This is the second GGDEF-EAL-encoding locus determined to be involved in the regulation of swarming: the first was previously characterized and namedscrABC(for “swarming and capsular ...
Yun-Kyeong, Kim, Linda L, McCarter
openaire   +2 more sources