Results 11 to 20 of about 2,948 (189)
PLoS Genetics, 2022 Bacterial second messengers are important for regulating diverse bacterial lifestyles. Cyclic di-GMP (c-di-GMP) is produced by diguanylate cyclase enzymes, named GGDEF proteins, which are widespread across bacteria.
Rebecca C Lowry +8 more
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Dual-function enzyme acts as a global c-di-GMP sink and local anti sigma factor antagonist to drive cellular differentiation. [PDF]
PLoS GeneticsSoil bacteria of the genus Streptomyces are natural producers of over two-thirds of clinically used antibiotics. Their ability to generate these valuable metabolites is tightly linked to a developmental program involving the transition from vegetative ...
Buse Cınar Cakmak +7 more
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Microbiology Spectrum, 2023 Colony pattern formations of bacteria with motility manifest complicated morphological self-organization phenomena. Leptolyngbya boryana is a filamentous cyanobacterium, which has been used as a genetic model organism for studying metabolism including ...
Kazuma Toida +10 more
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In silico comparative analysis of GGDEF and EAL domain signaling proteins from the Azospirillum genomes [PDF]
BMC Microbiology, 2018 Background The cyclic-di-GMP (c-di-GMP) second messenger exemplifies a signaling system that regulates many bacterial behaviors of key importance; among them, c-di-GMP controls the transition between motile and sessile life-styles in bacteria. Cellular c-
Alberto Ramírez Mata +4 more
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GGDEF-EAL domain proteins in bacterial physiology
, 2008 GGDEF and EAL domain proteins were identified in the chromosome of many bacteria. GGDEF domain proteins are generally diguanyl cyclases which synthesize the secondary messenger cyclic di-GMP. EAL domain proteins are generally c-di-GMP specific phosphodiesterase which degrade c-di-GMP.
Abdul Kader (33837)
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Systematic Nomenclature for GGDEF and EAL Domain-Containing Cyclic Di-GMP Turnover Proteins of Escherichia coli [PDF]
Journal of Bacteriology, 2016 ABSTRACT In recent years, Escherichia coli has served as one of a few model bacterial species for studying cyclic di-GMP (c-di-GMP) signaling. The widely used E. coli K-12 laboratory strains possess 29 genes encoding proteins with GGDEF and/or EAL domains, which include 12 ...
Hengge, Regine +7 more
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Functional analysis of GGDEF-EAL didomain-containing proteins in cyclic-di-GMP signaling [PDF]
, 2019 DOCTOR OF PHILOSOPHY (SBS)
Qi, Yaning
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Microbiology Research, 2018 RpfG is a member of a class of wide spread bacterial two-component regulators with an HD-GYP cyclic di-GMP phosphodiesterase domain. In the plant pathogen Xanthomonas campestris pv. campestris (Xcc), RpfG together with the sensor kinase RpfC regulates the synthesis of a range of virulence factors as a response to the cell-cell Diffusible Signaling ...
Shi-qi An, Ji-liang Tang
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A systematic analysis of the role of GGDEF-EAL domain proteins in virulence and motility in Xanthomonas oryzae pv. oryzicola [PDF]
Scientific Reports, 2016 AbstractThe second messenger c-di-GMP is implicated in regulation of various aspects of the lifestyles and virulence of Gram-negative bacteria. Cyclic di-GMP is formed by diguanylate cyclases with a GGDEF domain and degraded by phosphodiesterases with either an EAL or HD-GYP domain.
Wei, Chao +8 more
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Domain architecture of the Mycobacterium tuberculosis MabR (Rv2242), a member of the PucR transcription factor family [PDF]
HeliyonMabR (Rv2242), a PucR-type transcription factor, plays a crucial role in regulating mycolic acid biosynthesis in Mycobacterium tuberculosis. To understand its regulatory mechanisms, we determined the crystal structures of its N-terminal and C-terminal ...
Véronique Megalizzi +8 more
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