Results 71 to 80 of about 5,655 (194)

The MarR Family Transcriptional Regulator EmrR Negatively Regulates the Type III Secretion System (T3SS) and Positively Modulates Pathogenicity in Dickeya oryzae

Molecular Plant Pathology, Volume 27, Issue 4, April 2026.
This study revealed that the transcriptional regulator EmrR in Dickeya oryzae modulates virulence by regulating hrpL expression and c‐di‐GMP levels. It affects motility, biofilm formation, cellulase production and pathogenicity. EMSA and footprinting confirmed EmrR binds directly to the promoter of its target operon.
Mingfa Lv, Wenqi Huang, Ziwei Meng, Xiaojing Fan, Peng Li, Zeling Xu, Shaohua Chen, Xiaoyuan Chen, Jianuan Zhou, Lianhui Zhang, Yingying Cheng, Tao Zhuo, Ming Hu   +12 more
wiley   +1 more source

Characterization of Mycobacterium leprae diguanylate cyclases

, 2016
Mycobacterium leprae is the causative agent of leprosy, which is still a major health problem in several developing countries. Management of leprosy has been challenging because of the long incubation period of the disease and the development of a spectrum of clinical manifestations.
Rotcheewaphan, Suwatchareeporn, author, Belisle, John T., advisor, Borlee, Brad R., committee member, Brennan, Patrick J., committee member, Jackson, Mary, committee member, Prenni, Jessica E., committee member   +5 more
openaire   +1 more source

Expanded Functional Characterization and Optimization of Protein Expression in Treponema denticola Shuttle Plasmids

Molecular Oral Microbiology, Volume 41, Issue 2, Page 69-84, April 2026.
We report optimization of the Treponema denticola shuttle plasmid system by minimizing its size and by characterizing an array of promoter‐gene constructs for genetic complementation, including the first use in Treponema of a Tet‐inducible system for controlled expression of potentially toxic genes.
M. Paula Goetting‐Minesky, Valentina Godovikova, Prakaimuk Saraithong, Alexander H. Rickard, Brigette R. Crawley, Sara M. Agolli, Reagan L. Boyce, Trishna L. Appaji, J. Christopher Fenno   +8 more
wiley   +1 more source

Biofilms and cyclic di-GMP (c-di-GMP) signaling: lessons from Pseudomonas aeruginosa and other bacteria

, 2016
The cyclic di-GMP (c-di-GMP) second messenger represents a signaling system that regulates many bacterial behaviors and is of key importance for driving the lifestyle switch between motile loner cells and biofilm formers.
Filloux, A, Valentini, M
core   +2 more sources

Roles of the second messenger cyclic di-GMP in environmental adaptation of Sinorhizobium meliloti [PDF]

, 2017
Bacteria have evolved various systems for the integration of environmental signals to rapidly coordinate cellular pathways and adapt to changes in their environment.
Schäper, Simon
core   +1 more source

The Diguanylate Cyclase GcbA Facilitates Pseudomonas aeruginosa Biofilm Dispersion by Activating BdlA [PDF]

Journal of Bacteriology, 2015
ABSTRACT Biofilm dispersion is a highly regulated process that allows biofilm bacteria to respond to changing environmental conditions and to disseminate to new locations. The dispersion of biofilms formed by the opportunistic pathogen Pseudomonas aeruginosa is known to ...
Olga E, Petrova, Kathryn E, Cherny, Karin, Sauer   +2 more
openaire   +2 more sources

Bacterial Microbiome Composition and Functional Potentials Across Digestive Regions of Wild New Zealand Abalone (Haliotis iris)

New Zealand Journal of Marine and Freshwater Research, Volume 60, Issue 1, March 2026.
Abalone are valuable commercial marine gastropods, supporting both aquaculture and fishery markets. An important ecological aspect of their survival and physiological performance in a given habitat is a complex and balanced symbiotic relationship with microbes in their digestive system.
Jinchen Guo, Andrea C. Alfaro, Leonie Venter, Donnabella C. Lacap‐Bugler   +3 more
wiley   +1 more source

Cyclic di-GMP: second messenger extraordinaire [PDF]

, 2017
Cyclic dinucleotides (CDNs) are highly versatile signalling molecules that control various important biological processes in bacteria. The best-studied example is cyclic di-GMP (c-di-GMP).
Jenal, Urs, Lori, Christian, Reinders, Alberto   +2 more
core   +1 more source

Cyanobacteriochrome SesA Is a Diguanylate Cyclase That Induces Cell Aggregation in Thermosynechococcus [PDF]

Journal of Biological Chemistry, 2014
Cyanobacteria have unique photoreceptors, cyanobacteriochromes, that show diverse spectral properties to sense near-UV/visible lights. Certain cyanobacteriochromes have been shown to regulate cellular phototaxis or chromatic acclimation of photosynthetic pigments.
Gen, Enomoto, Ryouhei, Nomura, Takashi, Shimada, , Ni-Ni-Win, Rei, Narikawa, Masahiko, Ikeuchi   +5 more
openaire   +2 more sources

Microbial metabolites in tumor epigenetic regulation

iMeta, Volume 5, Issue 1, February 2026.
The gut microbiome modulates tumor epigenetic regulation through bioactive metabolites derived from dietary substrates. Microbiota‐produced SCFAs, secondary BAs, one‐carbon metabolites, and tryptophan‐derived ligands regulate histone acetylation, DNA methylation, and chromatin remodeling via HDAC, DNMT, AhR, and metabolic cofactor‐dependent pathways ...
Wangzheqi Zhang, Haoling Zhang, Yan Liao, Shuya Jiang, Haolong Zhang, Chenwei Huang, Zhijing Song, Rui Zhao, Ping Lu, Xiaohong Kang, Eryan Kong, Yalin Zhu, Wei Wang, Xuesong Liu, Yisheng Chen, Zhiwen Luo, Zhaoyu Li, Di Wang, Na Xing, Yadong Guo, Jingjing Zhang, Xiaojing Wang, Wenyi Wang, Mowaffaq Adam, Bakiah Shaharuddin, Muhamad Yusri Musa, Doblin Sandai, Chenglong Zhu, Aimin Jiang, Peng Luo, Zhijie Zhao, Zui Zou   +31 more
wiley   +1 more source