Results 91 to 100 of about 3,724 (177)

Analysis of CdgC as the major diguanylate cyclase in S. venezuelae

, 2021
The proliferation of Gram-positive soil bacteria Streptomyces is temporally and genetically coordinated with a complex developmental life cycle, including three main stages of differentiation: vegetative hyphal growth, formation of aerial mycelium and sporulation.
openaire   +1 more source

Antibiotic Persister Cells in Acinetobacter baumannii: Overview of Molecular Mechanisms and Removal Strategies

Environmental Microbiology, Volume 27, Issue 11, November 2025.
Antibiotic persister cells in Acinetobacter baumannii: review of the molecular mechanisms involved in this physiology, such as toxin/antitoxin, second messengers, SOS response, PAA or membranes; and elimination strategies such as antibiotics or phages.
Delphine Vergoz, Emmanuelle Dé, Corinne Loutelier‐Bourhis, Stéphane Alexandre   +3 more
wiley   +1 more source

Comparative Genomic Analysis Identifies FleQ and GcbB as Virulence‐Associated Factors in Pseudomonas syringae pv. tabaci Strains

Molecular Plant Pathology, Volume 26, Issue 11, November 2025.
Comparative genomic analysis between highly virulent strain Pta6605 and less virulent strain Pta7375 showed that point mutations in fleQ and gcbB are responsible for the contrasting virulence‐related phenotypes between the two strains. ABSTRACT Pseudomonas syringae pv.
Muhammad Taufiq Hidayat, Kei Yoshioka, Takafumi Nishimura, Shuta Asai, Sachiko Masuda, Ken Shirasu, Nanami Sakata, Mikihiro Yamamoto, Yoshiteru Noutoshi, Kazuhiro Toyoda, Yuki Ichinose, Hidenori Matsui   +11 more
wiley   +1 more source

ChIP-Seq and RNA-Seq reveal an AmrZ-mediated mechanism for cyclic di-GMP synthesis and biofilm development by Pseudomonas aeruginosa.

PLoS Pathogens, 2014
The transcription factor AmrZ regulates genes important for P. aeruginosa virulence, including type IV pili, extracellular polysaccharides, and the flagellum; however, the global effect of AmrZ on gene expression remains unknown, and therefore, AmrZ may ...
Christopher J Jones, David Newsom, Benjamin Kelly, Yasuhiko Irie, Laura K Jennings, Binjie Xu, Dominique H Limoli, Joe J Harrison, Matthew R Parsek, Peter White, Daniel J Wozniak   +10 more
doaj   +1 more source

Heterologous complementation analysis in E. coli of the diguanylate cyclase activity from single GGDEF domains encoded by At. caldus genes.

, 2015
The ability of GGDEF-domain proteins to synthesize c-di-GMP and to induce a Red phenotype on a Congo red agar plate (A) by the E. coli MG1655 wild type strain (1), AM70 diguanylate cyclase null-mutant strain (2) and E.
Douglas E. Rawlings (481576), Lina Ruiz (692628), Matías Castro (4865401), Shelly M. Deane (692627), Nicolas Guiliani (692629)   +4 more
core   +1 more source

Oxygen promotes biofilm formation of Shewanella putrefaciens CN32 through a diguanylate cyclase and an adhesin

, 2013
Although oxygen has been reported to regulate biofilm formation by several Shewanella species, the exact regulatory mechanism mostly remains unclear. Here, we identify a direct oxygen-sensing diguanylate cyclase (DosD) and reveal its regulatory role in ...
Zhou, Xian-Xuan, Wu, Chao, Song, Xiang-Ning, Yin, Hao, Han, Jun-Cheng, Li, Wen-Wei, Yu, Han-Qing, Zhao, Li-Ping, Tian, Li-Jiao, Cheng, Yuan-Yuan   +9 more
core   +1 more source

Echinacoside reduces intracellular c-di-GMP levels and potentiates tobramycin activity against Pseudomonas aeruginosa biofilm aggregates

npj Biofilms and Microbiomes
Cyclic diguanylate (c-di-GMP) is a central biofilm regulator in Pseudomonas aeruginosa, where increased intracellular levels promote biofilm formation and antibiotic tolerance.
Yu-Ming Cai, Feng Hong, Amber De Craemer, Jacob George Malone, Aurélie Crabbé, Tom Coenye   +5 more
doaj   +1 more source

A diguanylate cyclase regulates motility and biofilm formation in Bordetella bronchiseptica mediated by a GGDEF-EAL protein [PDF]

, 2019
Bordetella bronchiseptica is a bacterium that causes respiratory infections in a variety of mammalian hosts. We have already described c-di-GMP role in motility and biofilm formation. We previously showed that over expressing BdcA (Bordetella diguanylate
Zacca, F., Sisti, Federico, Fernández, Julieta, Gutiérrez, M. P., Belhart, K.   +4 more
core   +1 more source

Identification of an interaction between diguanylate cyclase CdgB and a putative interacting partner (PIP) in Streptomyces

Streptomyces is a group of filamentous bacteria, best known to produce diverse clinically important antibiotics. This group has a complex life cycle regulated by 3’-5’-cyclic diguanylic acid (c-diGMP).
Prada Mora, Juanita
core   +1 more source

Folding of the transcription factor Brinker and interactions of the bacterial second messenger c-di-GMP studied by NMR [PDF]

, 2013
Nuclear magnetic resonance (NMR) spectroscopy is a technique, which allows the non-invasive investigation of structures, dynamics and interactions of biomolecules.
Gentner, Martin
core   +1 more source