Results 81 to 90 of about 40,793 (179)

Serine Hydroxymethyltransferase ShrA (PA2444) Controls Rugose Small-Colony Variant Formation in Pseudomonas aeruginosa

open access: yesFrontiers in Microbiology, 2018
Pseudomonas aeruginosa causes many biofilm infections, and the rugose small-colony variants (RSCVs) of this bacterium are important for infection. We found here that inactivation of PA2444, which we determined to be a serine hydroxymethyltransferase ...
Mingming Pu   +4 more
doaj   +1 more source

TolC Is Required for a Mixed‐Linkage β‐Glucan (MLG) Biosynthesis: Engineering Bacteria for MLG Overproduction

open access: yesMicrobial Biotechnology, Volume 19, Issue 8, August 2026.
TolC is identified as an essential component of the mixed‐linkage β‐glucan (MLG) biosynthetic machinery in Sinorhizobium meliloti, likely enabling polymer export. Co‐expression of tolC, bgsBA, and pleD* significantly enhances MLG production and enables its synthesis in non‐native bacterial hosts.
L. Ruiz‐Sáez   +6 more
wiley   +1 more source

To Move or Not to Move: When and How Bacteria Suppress Flagellar Motility

open access: yesMolecular Microbiology, Volume 126, Issue 2, Page 173-189, August 2026.
Motility cessation in bacteria is a key regulatory strategy that provides multiple survival advantages including enhanced community cooperation, niche adaptation and evasion of host immune responses. This process is controlled by associated mechanisms such as post‐translational modifications and second messenger signalling that stabilise non‐motile ...
Fatemeh Mohaghegh   +2 more
wiley   +1 more source

An evolutionary optimization of a rhodopsin-based phototrophic metabolism in Escherichia coli

open access: yesMicrobial Cell Factories, 2017
Background The expression of the Gloeobacter rhodopsin (GR) in a chemotrophic Escherichia coli enables the light-driven phototrophic energy generation. Adaptive laboratory evolution has been used for acquiring desired phenotype of microbial cells and for
Hyun Aaron Kim   +9 more
doaj   +1 more source

Naturally Occurring CodY Variants Alter Ligand Binding, DNA Target Affinity, and Virulence in Clostridioides difficile

open access: yesMolecular Microbiology, Volume 126, Issue 1, Page 98-110, July 2026.
Single amino acid substitutions in the global regulator CodY can alter nutrient sensing and virulence regulation in Clostridioides difficile. We show that the CodY(Y146N) and CodY(V58A) variants display altered ligand binding and reduced promoter binding, leading to derepression of toxin regulatory pathways and increased virulence in vivo.
Md Kamrul Hasan   +2 more
wiley   +1 more source

Heterologous complementation analysis in E. coli of the diguanylate cyclase activity from single GGDEF domains encoded by At. caldus genes.

open access: yes, 2015
The ability of GGDEF-domain proteins to synthesize c-di-GMP and to induce a Red phenotype on a Congo red agar plate (A) by the E. coli MG1655 wild type strain (1), AM70 diguanylate cyclase null-mutant strain (2) and E.
Douglas E. Rawlings (481576)   +4 more
core   +1 more source

Diguanylate Cyclases Control Magnesium-Dependent Motility ofVibrio fischeri [PDF]

open access: yesJournal of Bacteriology, 2006
ABSTRACTFlagellar biogenesis and hence motility ofVibrio fischeridepends upon the presence of magnesium. In the absence of magnesium, cells contain few or no flagella and are poorly motile or nonmotile. To dissect the mechanism by which this regulation occurs, we screened transposon insertion mutants for those that could migrate through soft agar ...
Therese M, O'Shea   +4 more
openaire   +2 more sources

Forecasting Root Rot Disease through Predictive Microbial Functional Profiling

open access: yesAdvanced Science, Volume 13, Issue 23, 23 April 2026.
Predicting soil‐borne disease moves beyond observation with a framework that elevates microbial functional genes into reliable forecasting biomarkers. By coupling targeted qPCR assays for core stress‐response genes with machine learning, this method detects root rot risks in pre‐symptomatic soils with over 80% accuracy.
Chuan You   +11 more
wiley   +1 more source

Enhanced Exoelectrogenic Activity of Cupriavidus metallidurans in Bioelectrochemical Systems through the Expression of a Constitutively Active Diguanylate Cyclase

open access: yes, 2022
Electroactive bacteria have a wide range of applications, including electricity production, bioremediation, and the sensing of toxic compounds. Bacterial biofilm formation is often mediated by the second messenger cyclic guanosine monophosphate (c-di-GMP)
Francesca Formicola   +6 more
core   +1 more source

Cyclic di-GMP-dependent signaling pathways in the pathogenic Firmicute Listeria monocytogenes.

open access: yesPLoS Pathogens, 2014
We characterized key components and major targets of the c-di-GMP signaling pathways in the foodborne pathogen Listeria monocytogenes, identified a new c-di-GMP-inducible exopolysaccharide responsible for motility inhibition, cell aggregation, and ...
Li-Hong Chen   +7 more
doaj   +1 more source

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