Results 101 to 110 of about 40,793 (179)

Identification of two different chemosensory pathways in representatives of the genus Halomonas

BMC Genomics, 2018
Background Species of the genus Halomonas are salt-tolerant organisms that have a versatile metabolism and can degrade a variety of xenobiotic compounds, utilizing them as their sole carbon source.
Ana Florencia Gasperotti, María Victoria Revuelta, Claudia Alicia Studdert, María Karina Herrera Seitz   +3 more
doaj   +1 more source

BolA Is Required for the Accurate Regulation of c-di-GMP, a Central Player in Biofilm Formation

mBio, 2017
The bacterial second messenger cyclic dimeric GMP (c-di-GMP) is a nearly ubiquitous intracellular signaling molecule involved in the transition from the motile to the sessile/biofilm state in bacteria.
Ricardo N. Moreira, Clémentine Dressaire, Susana Barahona, Lisete Galego, Volkhard Kaever, Urs Jenal, Cecília M. Arraiano   +6 more
doaj   +1 more source

c-di-GMP-linked phenotypes are modulated by the interaction between a diguanylate cyclase and a polar hub protein

, 2017
Summaryc-di-GMP is a major player in the decision between biofilm and motile lifestyles. Several bacteria present a large number of c-di-GMP metabolizing proteins, thus a fine-tuning of this nucleotide levels may occur.
Pio Colepicolo, Ana Laura Boechat, Gianlucca G. Nicastro, Thays de O. Pereira, Eliezer Stefanello, Christophe Bordi, Gilberto H. Kaihami, Jacobo Hernandez-Montelongo, Regina L. Baldini, André A. Pulschen   +9 more
core   +1 more source

The Diguanylate Cyclase SadC Is a Central Player in Gac/Rsm-Mediated Biofilm Formation in Pseudomonas aeruginosa [PDF]

, 2014
Pseudomonas aeruginosa is a Gram-negative opportunistic human pathogen and a threat for immunocompromised and cystic fibrosis patients. It is responsible for acute and chronic infections and can switch between these lifestyles upon taking an informed ...
Jaeger, Tina, Hui, K, Filloux, A, Moscoso, Joana A., Jenal, U, Valentini, Martina, Jaeger, T, Hui, Kailyn, Valentini, M, Moscoso, JA, Moscoso, Joana A, Filloux, Alain, Jenal, Urs, Filloux A, Hui K, Jenal U, Moscoso JA, Jaeger T, Valentini M   +18 more
core   +1 more source

Contribution of Physical Interactions to Signaling Specificity between a Diguanylate Cyclase and Its Effector

mBio, 2015
Cyclic diguanylate (c-di-GMP) is a bacterial second messenger that controls multiple cellular processes. c-di-GMP networks have up to dozens of diguanylate cyclases (DGCs) that synthesize c-di-GMP along with many c-di-GMP-responsive target proteins that ...
Kurt M. Dahlstrom, Krista M. Giglio, Alan J. Collins, Holger Sondermann, George A. O’Toole   +4 more
doaj   +1 more source

Multiple diguanylate cyclase-coordinated regulation of pyoverdine synthesis in Pseudomonas aeruginosa [PDF]

, 2015
The nucleotide signalling molecule bis-(3'-5')-cyclic dimeric guanosine monophosphate (c-di-GMP) plays an essential role in regulating microbial virulence and biofilm formation. C-di-GMP is synthesized by diguanylate cyclase (DGC) enzymes and degraded by
Joey Kuok Hoong Yam, Givskov, Michael, Yicai Chen, Liu, Yang, Anee Mohanty, Liang Yang, Tolker-Nielsen, Tim, Song Lin Chua, Yang, Liang, Yang Liu, Chen, Yicai, Nielsen, Thomas Eiland, Mingjun Yuan, Tim Tolker‐Nielsen, Cao, Bin, Thomas E. Nielsen, Yam, Joey Kuok Hoong, Michael Givskov, Nielsen, Thomas E., Yuan, Mingjun, Chua, Song Lin, Mohanty, Anee, Bin Cao   +22 more
core   +1 more source

Oxygen and Bis(3′,5′)-cyclic Dimeric Guanosine Monophosphate Binding Control Oligomerization State Equilibria of Diguanylate Cyclase-Containing Globin Coupled Sensors

, 2016
Bacteria sense their environment to alter phenotypes, including biofilm formation, to survive changing conditions. Heme proteins play important roles in sensing the bacterial gaseous environment and controlling the switch between motile and sessile ...
Shannon Rivera (3359585), Emily E. Weinert (2127613), Shawnna C. Joynt (3359588), D. Douglas Deer (3359591), Justin L. Burns (3359582), David Dvorak (3359594)   +5 more
core   +1 more source

The Inhibitory Site of a Diguanylate Cyclase Is a Necessary Element for Interaction and Signaling with an Effector Protein [PDF]

, 2016
Many bacteria contain large cyclic diguanylate (c-di-GMP) signaling networks made of diguanylate cyclases (DGCs) and phosphodiesterases that can direct cellular activities sensitive to c-di-GMP levels.
Giglio, Krista M, Dahlstrom, Kurt M, O\u27Toole, George A, Sondermann, Holger   +3 more
core   +1 more source

Interplay of virulence factors and signaling molecules: albumin and calcium-mediated biofilm regulation in Bordetella bronchiseptica

Journal of Bacteriology
Bordetella bronchiseptica, a respiratory pathogen capable of infecting various mammals, including humans, is associated with chronic infections. B.
Sabrina Laura Mugni, Nicolás Ambrosis, George A. O´Toole, Federico Sisti, Julieta Fernández   +4 more
doaj   +1 more source

Characterization of diguanylate cyclase metabolism-related gene in Azorhizobium caulinodans ORS571

, 2019
[Objective] To study the phenotypes of Azorhizobium caulinodansORS571 mutant strain lacking the diguanylate cyclase AZC-2412, and to explore its functional mechanism.
杨学智, 孙雨, 李润植, 沈日敏, 解志红   +4 more
core