Results 101 to 110 of about 3,724 (177)

A GGDEF and EAL domain-containing protein in Pseudomonas syringae pv. actinidiae regulates virulence via its diguanylate cyclase activity

Phytopathology Research
Kiwifruit bacterial canker (KBC), caused by Pseudomonas syringae pv. actinidiae (Psa), poses a severe threat to the global kiwifruit industry, highlighting the urgent need to elucidate its pathogenic mechanisms. Cyclic diguanylate monophosphate (c-di-GMP)
Yudi Wang, Mingming Yang, Jinfang Zhou, Xianwei Xie, Jiabing Ma, Yao Wang, Xihui Shen, Lili Huang   +7 more
doaj   +1 more source

Identification of two different chemosensory pathways in representatives of the genus Halomonas

BMC Genomics, 2018
Background Species of the genus Halomonas are salt-tolerant organisms that have a versatile metabolism and can degrade a variety of xenobiotic compounds, utilizing them as their sole carbon source.
Ana Florencia Gasperotti, María Victoria Revuelta, Claudia Alicia Studdert, María Karina Herrera Seitz   +3 more
doaj   +1 more source

Contribution of Physical Interactions to Signaling Specificity between a Diguanylate Cyclase and Its Effector

mBio, 2015
Cyclic diguanylate (c-di-GMP) is a bacterial second messenger that controls multiple cellular processes. c-di-GMP networks have up to dozens of diguanylate cyclases (DGCs) that synthesize c-di-GMP along with many c-di-GMP-responsive target proteins that ...
Kurt M. Dahlstrom, Krista M. Giglio, Alan J. Collins, Holger Sondermann, George A. O’Toole   +4 more
doaj   +1 more source

Structural biology of bacterial response regulator proteins and their complexes with cognate ligands [PDF]

, 2009
Two bacterial response regulator systems were studied in this thesis. NMR spectroscopy and X-ray crystallography were used to determine the structures of both domains of the antibiotic sensor TipAL, as well as of the c-di-GMP receptor PA4608, in ...
Allan, Martin Georg
core   +1 more source

BolA Is Required for the Accurate Regulation of c-di-GMP, a Central Player in Biofilm Formation

mBio, 2017
The bacterial second messenger cyclic dimeric GMP (c-di-GMP) is a nearly ubiquitous intracellular signaling molecule involved in the transition from the motile to the sessile/biofilm state in bacteria.
Ricardo N. Moreira, Clémentine Dressaire, Susana Barahona, Lisete Galego, Volkhard Kaever, Urs Jenal, Cecília M. Arraiano   +6 more
doaj   +1 more source

The Diguanylate Cyclase SadC Is a Central Player in Gac/Rsm-Mediated Biofilm Formation in Pseudomonas aeruginosa [PDF]

, 2014
Pseudomonas aeruginosa is a Gram-negative opportunistic human pathogen and a threat for immunocompromised and cystic fibrosis patients. It is responsible for acute and chronic infections and can switch between these lifestyles upon taking an informed ...
Jaeger, Tina, Hui, K, Filloux, A, Moscoso, Joana A., Jenal, U, Valentini, Martina, Jaeger, T, Hui, Kailyn, Valentini, M, Moscoso, JA, Moscoso, Joana A, Filloux, Alain, Jenal, Urs   +12 more
core   +1 more source

Phylogenetic Analysis and Characterization of Diguanylate Cyclase and Phosphodiesterase in Planktonic Filamentous Cyanobacterium Arthrospira sp. [PDF]

Int J Mol Sci, 2023
Wang K, Li W, Cui H, Qin S.
europepmc   +1 more source

Genomic Island-Encoded Diguanylate Cyclase from Vibrio alginolyticus Regulates Biofilm Formation and Motility in Pseudoalteromonas. [PDF]

Microorganisms, 2023
Cai T, Tang H, Du X, Wang W, Tang K, Wang X, Liu D, Wang P.   +7 more
europepmc   +1 more source

Interplay of virulence factors and signaling molecules: albumin and calcium-mediated biofilm regulation in Bordetella bronchiseptica

Journal of Bacteriology
Bordetella bronchiseptica, a respiratory pathogen capable of infecting various mammals, including humans, is associated with chronic infections. B.
Sabrina Laura Mugni, Nicolás Ambrosis, George A. O´Toole, Federico Sisti, Julieta Fernández   +4 more
doaj   +1 more source

Intact and mutated Shigella diguanylate cyclases increase c-di-GMP

Journal of Biological Chemistry
The intracellular human pathogen Shigella invades the colonic epithelium to cause disease. Prior to invasion, this bacterium navigates through different environments within the human body, including the stomach and the small intestine. To adapt to changing environments, Shigella uses the bacterial second messenger cyclic di-GMP (c di-GMP) signaling ...
Ruchi Ojha, Stefanie Krug, Prentiss Jones, Benjamin J. Koestler   +3 more
openaire   +2 more sources