Results 261 to 270 of about 470,032 (357)

Myricetin Potentiates Antibiotics Against Resistant <i>Pseudomonas aeruginosa</i> by Disrupting Biofilm Formation and Inhibiting Motility Through FimX-Mediated c-di-GMP Signaling Interference. [PDF]

Biology (Basel)
Zeng D, Jiao F, Yang Y, Dou S, Yu J, Yu X, Zhou Y, Xue J, Li X, Duan H, Zhang Y, Guo J, Yang W.   +12 more
europepmc   +1 more source

Tlr0485 is a cAMP-activated c-di-GMP phosphodiesterase in a cyanobacterium <i>Thermosynechococcus</i>

, 2020
Gen Enomoto, Ayako Kamiya, Yukiko Okuda, Rei Narikawa, Masahiko Ikeuchi   +4 more
openalex   +2 more sources

From Genome to Geroscience: How DNA Damage Shapes Systemic Decline

BioEssays, EarlyView.
Persistent DNA damage triggers systemic secretory responses including damage‐associated molecular patterns (DAMPs), the senescence‐associated secretory phenotype (SASP), and extracellular vesicles (EVs). This non‐cell‐autonomous signaling disrupts intercellular communication, driving organism‐wide dysfunction and aging, and offering new therapeutic ...
Athanasios Siametis, George A. Garinis
wiley   +1 more source

Adjunctive beneficial effect of c-di-GMP, a STING agonist, in enhancing protective efficacy of TLR4-adjuvanted tuberculosis subunit vaccine formulations. [PDF]

J Biomed Sci
Kwon KW, Choi E, Kim H, Kim HW, Choi S, Lee S, Ha SJ, Shin SJ.   +7 more
europepmc   +1 more source

A fluorescence-based high-throughput screening method for determining the activity of diguanylate cyclases and c-di-GMP phosphodiesterases

, 2020
Ziqiang Wang, Teng-Fei Xuan, Jun Liu, Wei‐Min Chen, Jing Lin   +4 more
openalex   +2 more sources

Unveiling the complexity of cellular senescence in cancers: From mechanism to therapeutic opportunities

BMEMat, EarlyView.
This review highlights the complex roles of cellular senescence in cancer progression and suppression, discusses the mechanisms and regulatory pathways involved, and evaluates the efficacy of the “One‐Two punch” sequential treatment approach while addressing emerging challenges in this novel therapeutic strategy.
Qiuming Pan, Ye Zhu, Zhi Ye, Huayang Zhang, Junxi Wang, Guozhong Yi, Zhiyong Li, Rongyang Xu, Luyao Wang, Zhenzhen Wu, Songtao Qi, Guanglong Huang, Shanqiang Qu   +12 more
wiley   +1 more source

Echinacoside reduces intracellular c-di-GMP levels and potentiates tobramycin activity against Pseudomonas aeruginosa biofilm aggregates. [PDF]

NPJ Biofilms Microbiomes
Cai YM, Hong F, De Craemer A, Malone JG, Crabbé A, Coenye T.   +5 more
europepmc   +1 more source

434: Interspecies signaling during cystic fibrosis airway infection: How cAMP and c-di-GMP direct Pseudomonas aeruginosa chemotaxis toward Staphylococcus aureus

, 2021
Kaitlin D Yarrington, Dominique H. Limoli   +1 more
openalex   +1 more source

Continuous purification of a parvovirus using two aqueous two‐phase extraction steps

Biotechnology Progress, EarlyView.
Abstract Aqueous two‐phase systems (ATPS) are a liquid–liquid extraction method that offers low‐cost, continuous‐adaptable virus purification. A two‐step ATPS using polyethylene glycol (PEG) and sodium citrate that recovered 66% of infectious porcine parvovirus with 2.0 logs of protein removal and 1.0 logs of DNA removal in batch has now been run ...
Natalie M. Nold, Sheridan Waldack, Grace James, Trisha Colling, Lynn Manchester, Taravat Sarvari, Amanda Bekkala, Seth A. Kriz, Madison Baldwin, Emily Agustin‐Mazariegos, Michael J. Betenbaugh, Caryn L. Heldt   +11 more
wiley   +1 more source

Identification of FleQ from Pseudomonas aeruginosa as a c‐di‐GMP‐responsive transcription factor

Molecular Microbiology, 2008
J. W. Hickman, C. Harwood
semanticscholar   +1 more source