Results 141 to 150 of about 2,467,830 (354)

Light-driven C–H activation mediated by 2D transition metal dichalcogenides

Nature Communications
C–H bond activation enables the facile synthesis of new chemicals. While C–H activation in short-chain alkanes has been widely investigated, it remains largely unexplored for long-chain organic molecules.
Jingang Li, Di Zhang, Zhongyuan Guo, Zhihan Chen, Xi Jiang, Jonathan M. Larson, Haoyue Zhu, Tianyi Zhang, Yuqian Gu, Brian W. Blankenship, Min Chen, Zilong Wu, Suichu Huang, Robert Kostecki, Andrew M. Minor, Costas P. Grigoropoulos, Deji Akinwande, Mauricio Terrones, Joan M. Redwing, Hao Li, Yuebing Zheng   +20 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Competing C–H and C–F bond activation reactions of a fluorinated olefin at Rh: a fluorido vinylidene complex as an intermediate in an unprecedented dehydrofluorination step

, 2022
María Talavera, Thomas Braun
openalex   +2 more sources

Iron-Catalyzed Aza-Annulative π-Extension with Alkynes via C–H Activation using an Oxidative Auxiliary

: Aza-annulative π-extension (AAPE) reactions offer a potent pathway to create novel donor-acceptor conjugated materials by integrating an imine moiety into the conjugated system, serving as an electron-accepting unit.
Eiichi, Nakamura, Rui, Shang, Yan , Zhang, Shota, Fukuma   +3 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Correction: Palladium(ii)-catalyzed vinylic geminal double C–H activation and alkyne annulation reaction: synthesis of pentafulvenes

, 2023
Jyotshna Phukon, Sanjib Gogoi
openalex   +2 more sources

Chemodivergent assembly of ortho-functionalized phenols with tunable selectivity via rhodium(III)-catalyzed and solvent-controlled C-H activation [PDF]

, 2021
Haiman Zhang, Shuang Lin, Hui Gao, Kaixin Zhang, Yi Wang, Zhi Zhou, Wei Yi   +6 more
openalex   +1 more source

C―H Activation [PDF]

Acta Physico-Chimica Sinica, 2019
openaire   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Cascade C‒H-Activated Polyannulations toward Ring-Fused Heteroaromatic Polymers for Intracellular pH Mapping and Cancer Cell Killing [PDF]

, 2022
Kang Wang, Saisai Yan, Ting Han, Qian Wu, Neng Yan, Miaomiao Kang, Jinyin Ge, Dong Wang, Ben Zhong Tang   +8 more
openalex   +1 more source