Results 121 to 130 of about 2,467,830 (354)

Cobalt-catalyzed directed C–H alkenylation of pivalophenone N–H imine with alkenyl phosphates

Beilstein Journal of Organic Chemistry, 2018
A cobalt–N-heterocyclic carbene (NHC) catalyst efficiently promotes an ortho C–H alkenylation reaction of pivalophenone N–H imine with an alkenyl phosphate. The reaction tolerates various substituted pivalophenone N–H imines as well as cyclic and acyclic
Wengang Xu, Naohiko Yoshikai
doaj   +1 more source

Modular, Stereocontrolled Cβ–H/Cα–C Activation of Alkyl Carboxylic Acids

, 2019
The union of two powerful transformations, directed C–H activation and decarboxylative cross-coupling, for the enantioselective synthesis of vicinally functionalized alkyl, carbocyclic, and heterocyclic compounds is described.
Karla S., Feu, Kerstin, Gagaring, Liang, Hu, Heather L., Osswald, Ming, Shang, jin-quan, yu, Stuart, Schreiber, Nobutaka, Kato, Miao, Chen, Phil, Baran, Lisa M., Barton, Shengyang, Ni, Gang, Chen, Paula, Fernández-Canelas, Julien C., Vantourout, Bruno, Melillo, Rohan R., Merchant, Tian, qin, Case W., McNamara   +18 more
core   +1 more source

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

FEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia, Anna Dósa, Asha Kiran Maddali, András Jipa, Hajnalka Laczkó‐Dobos, Péter Lőw, Gábor Juhász   +6 more
wiley   +1 more source

Direct Synthesis of 3‐Aryl Substituted Isocoumarins and Phthalides through Palladium Acetate Catalyzed C(sp²)−H Activation in Ionic Liquids

, 2022
Andrea Aloia, Michele Casiello, Lucia D’Accolti, Caterina Fusco, Angelo Nacci, Antonio Monopoli   +5 more
openalex   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Rh(iii)-catalyzed synthesis of dibenzo[b,d]pyran-6-ones from aryl ketone O-acetyl oximes and quinones via C–H activation and C–C bond cleavage

, 2022
Wei Yang, Haonan Zhang, Yu Liu, Cuiman Tang, Xiaohui Xu, Jiaqi Liu   +5 more
openalex   +2 more sources

Palladium-Catalyzed Divergent Cyclopropanation by Regioselective Solvent-Driven C(sp3)?H Bond Activation

, 2018
Reported is a tandem palladium-catalyzed Heck/regioselective C(sp3)?H activation reaction for the divergent synthesis of spiro- and fused-cyclopropanated indolines from N-methallylated 2-bromoarylamides. The regioselectivity of the C?H bond activation in
Da Sol Chung, Jiyong Park, Joo Hyun Lee, UBin Kim, Hyunjoong Kim, Mu-Hyun Baik, Sang-gi Lee, Jae Sung Lee, Won Koo Lee, Ho Ryu   +9 more
core  

Rhodaelectrocatalysis for Annulative C−H Activation: Polycyclic Aromatic Hydrocarbons through Versatile Double Electrocatalysis

, 2019
Rapid access to structurally diversified polycyclic aromatic hydrocarbons (PAHs) in a controlled manner is of key significance in materials sciences.
Wei‐Jun Kong, Lars H. Finger, Ackermann, Lutz, João C. A. Oliveira, Oliveira, João C. A., Kong, Wei‐Jun, Finger, Lars H., Lutz Ackermann   +7 more
core   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

ChemInform Abstract: A Novel Prins Cyclization Through Benzylic/Allylic C—H Activation. [PDF]

, 2009
Binxun Yu, Tuo Jiang, Junpeng Li, Yingpeng Su, Xinfu Pan, Xuegong She   +5 more
openalex   +1 more source