Results 101 to 110 of about 2,467,830 (354)
C—H oxidation reactions in complex molecule synthesis: application and development
, 2011 Among the frontier challenges in chemistry in the 21st century are the interconnected goals of increasing synthetic efficiency and diversity in the construction of complex molecules.
Stang, Erik M.
core
, 2019 Chiral rhodium(III) cyclopentadienyl catalysts ((CpRhIII)-Rh-X) play significant roles in asymmetric arene C-H activation. Rh/Ir-catalyzed couplings of arenes and strained rings have been well-studied, but they have been limited to racemic systems ...
Yang, Xifa, Zheng, Guangfan, Li, Xingwei
core +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
3d Transition Metals for C–H Activation
Chemical Reviews, 2018 C-H activation has surfaced as an increasingly powerful tool for molecular sciences, with notable applications to material sciences, crop protection, drug discovery, and pharmaceutical industries, among others. Despite major advances, the vast majority of these C-H functionalizations required precious 4d or 5d transition metal catalysts. Given the cost-
Parthasarathy Gandeepan +5 more
openaire +4 more sources
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Corrigendum: Grignard‐Type Arylation of Aldehydes via a Rhodium‐Catalyzed C−H Activation under Mild Conditions [PDF]
, 2022 Luo Yang +2 more
openalex +1 more source
Rhodium(III)-Catalyzed C-C Coupling between Arenes and Aziridines by C-H Activation
, 2013 Rhodium(III)-Catalyzed C-C Coupling between Arenes and Aziridines by C-H ...
Wan, Boshun +6 more
core +1 more source
, 2020 © 2020 Wiley-VCH Verlag GmbH & Co. KGaA, WeinheimThe utilizations of omnipresent, thermodynamically stable amides and aliphatic C(sp3)−H bonds for various functionalizations are ongoing challenges in catalysis.
Geun Seok Lee +5 more
core +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source