Results 91 to 100 of about 2,467,830 (354)

Selective Borylation of C(sp3)−H Bond of Methyl Ethers Catalyzed by Iron Complexes Bearing Anionic Benzene‐Based PCP‐Pincer Ligands

ChemistryEurope
Highly selective catalytic C(sp3)−H borylation of methoxy groups has been achieved using newly synthesized iron complexes bearing benzene‐based PCP‐type pincer ligands as catalysts. Reactions of various aryl and alkyl methyl ethers as substrates with bis(
Shogo Kuriyama, Yuto Suga, Ken Sakata, Yoshiaki Nishibayashi   +3 more
doaj   +1 more source

Non-Oxidative Activation of C-H and Derict Conversion of Methane into Ethylene and Aromatics

, 2012
Non-Oxidative Activation of C-H and Derict Conversion of Methane into Ethylene and ...
包信和
core  

Selective C–H Activation of Unprotected Allylamines by Control of Catalyst Speciation

, 2023
An outstanding challenge in the Pd-catalyzed functionalization of allylamines is the control of stereochemistry. Terminal alkenes preferentially undergo Heck-type reactions, while internal alkenes may undergo a mixture of Heck and C–H activation ...
Ankita, Mishra, Vinod, Landge, Michael, Young, Audrey, Bonds, Waruna, Thotamune, Indunil, Alahakoon, Ajith, Karunarathne   +6 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Participation of c-FLIP in NLRP3 and AIM2 inflammasome activation

, 2017
Cellular FLICE-inhibitory protein (c-FLIP) is an inhibitor of caspase-8 and is required for macrophage survival. Recent studies have revealed a selective role of caspase-8 in noncanonical IL-1 beta production that is independent of caspase-1 or ...
賴明宗, Wu, Y-H;Kuo, W-C;Wu, Y-J;Yang, K-T;Chen, S-T;Jiang, S-T;Gordy, C.;He, Y-W;Lai, M-Z   +1 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

A Generalized Approach for Distal C–H Arylation of Organic Building Blocks: Unveiling the Role of Counter Anion

Advanced Science
Aryl–aryl coupling at remote C–H sites remain a formidable challenge in organic synthesis, particularly for electronically biased arenes and heteroarenes.
Jagrit Grover, Gaurav Prakash, Astam Mandal, Devika Ghosh, Siddhartha Maiti, Claire Empel, Debabrata Maiti   +6 more
doaj   +1 more source

Cobalta‐Electrocatalyzed C−H Activation in Biomass‐Derived Glycerol: Powered by Renewable Wind and Solar Energy

, 2020
Aqueous glycerol was identified as a renewable reaction medium for metalla‐electrocatalyzed C−H activation powered by sustainable energy sources. The renewable solvent was employed for cobalt‐catalyzed C−H/N−H functionalizations under mild conditions ...
Gleb A. Chesnokov, Chesnokov, Gleb A., Ackermann, Lutz, Tjark H. Meyer, Meyer, Tjark H., Lutz Ackermann   +5 more
core   +1 more source

Mechanism of the Arene-Limited Nondirected C–H Activation of Arenes with Palladium

, 2021
Recently palladium catalysts have been discovered that enable the directing group-free C–H activation of arenes without requiring an excess of the arene substrate, thereby enabling methods for the late-stage modification of complex organic molecules. The
Philipp, Wedi, Christian, Mück-Lichtenfeld, Mirxan, Farizyan, Klaus, Bergander, Manuel, van Gemmeren   +4 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source