miRNA‑29a inhibits the proliferation of HUVECs by regulating the ITGB1/β‑catenin/c‑Myc pathway. [PDF]
Sun Q +8 more
europepmc +1 more source
The GFPT2/O-GlcNAcylation/c-Myc axis promotes bladder cancer progression. [PDF]
Xie H +9 more
europepmc +1 more source
Activation of c-Myc confers resistance to venetoclax via inhibition of Bim in t(8;21)-positive acute myeloid leukemia. [PDF]
Yin Z +7 more
europepmc +1 more source
Moderate downregulation of NDUFA13 promotes cardiomyocytes proliferation and heart regeneration through the glycolysis/c‑Myc/<i>Ccnd1</i> axis. [PDF]
Gao Y +5 more
europepmc +1 more source
SerpinB7 promotes c-Myc-mediated glycolysis by interacting with ANXA2 to facilitate the progression of non-small cell lung cancer. [PDF]
Zhao F +24 more
europepmc +1 more source
CX26 promotes pancreatic cancer progression by competitively inhibiting interaction of c-Myc with PSMD2 and enhancing c-Myc stability. [PDF]
He C +5 more
europepmc +1 more source
Related searches:
Both genetic and epigenetic mechanisms intimately regulate cancer development and chemoresistance. Different genetic alterations are observed in multiple genes, and most are irreversible.
Homa Fatma, S. Maurya, Hifzur R Siddique
semanticscholar +1 more source
c-Myc-driven Hepatocarcinogenesis
Anticancer Research, 2021Dysregulation of the c-Myc gene is frequently found in human hepatocellular carcinoma (HCC), often accompanied by genetic and epigenetic alterations in other cancer-related genes. Here, we investigated the tumorigenic potential of c-Myc in diverse genetic environments in which the Ras, Wnt/β-catenin, Sonic hedgehog, or P53 pathways were either ...
Hyuk, Moon +2 more
openaire +2 more sources
Recent Update on Targeting c-MYC G-Quadruplexes by Small Molecules for Anticancer Therapeutics.
Journal of Medicinal Chemistry, 2020Guanine-rich DNA sequences have the propensity to adopt four-stranded tetrahelical G-quadruplex (G4) structures that are overrepresented in gene promoters. The structural polymorphism and physicochemical properties of these non-Watson-Crick G4 structures
Ritapa Chaudhuri +3 more
semanticscholar +1 more source

