Within-subject variation of C-reactive protein and high-sensitivity C-reactive protein: A systematic review and meta-analysis. [PDF]
PLoS ONEBackgroundC-reactive protein (CRP) and high-sensitivity C-reactive protein (hsCRP) are measures of inflammation used in diagnosis, to guide treatment decisions, and in disease prediction.
Alex Gough +3 more
doaj +2 more sources
Diagnosing serious infections in acutely ill children in ambulatory care (ERNIE 2 study protocol, part A): diagnostic accuracy of a clinical decision tree and added value of a point-of-care C-reactive protein test and oxygen saturation [PDF]
, 2014 Background: Acute illness is the most common presentation of children to ambulatory care. In contrast, serious infections are rare and often present at an early stage. To avoid complications or death, early recognition and adequate referral are essential.
Aertgeerts, B. +7 more
core +10 more sources
Systemic inflammation predicts all-cause mortality: a Glasgow Inflammation Outcome Study [PDF]
, 2015 Introduction: Markers of the systemic inflammatory response, including C-reactive protein and albumin (combined to form the modified Glasgow Prognostic Score), as well as neutrophil, lymphocyte and platelet counts have been shown to be prognostic of ...
Fletcher, Colin D. +5 more
core +6 more sources
Differentiating Viral and Bacterial Infections: A Machine Learning Model Based on Routine Blood Test Values [PDF]
Heliyon, Volume 10, ISSUE 8, e29372, Cell, April 30, 2024, 2023 The growing threat of antibiotic resistance necessitates accurate differentiation between bacterial and viral infections for proper antibiotic administration. In this study, a Virus vs. Bacteria machine learning model was developed to distinguish between these infection types using 16 routine blood test results, C-reactive protein concentration (CRP ...
arxiv +1 more source
Association between C-reactive protein with all-cause mortality in ELSA-Brasil cohort [PDF]
, 2020 Background: High-sensitive C-reactive protein (hsCRP) has been proposed as a marker of incident cardiovascular disease and vascular mortality, and it may also be a marker of non-vascular mortality.
Alvim Matos, Sheila M. +10 more
core +2 more sources
Dependence of C-Reactive Protein & Cholesterol [PDF]
Kirkuk Journal of Science, 2011 This study had been designed to illustrate the relationship between immunological and biochemical abnormalities in patients with coronary heart disease (CHD) in Dohuk. These patients were referred to the general Azadi hospital in Dohuk for investigation.
Malika K. Najeeb Al Barwari +1 more
doaj +1 more source
Therapeutic Lowering of C-Reactive Protein
Frontiers in Immunology, 2021 In the blood of healthy individuals C-reactive protein (CRP) is typically quite scarce, whereas its blood concentration can rise robustly and rapidly in response to tissue damage and inflammation associated with trauma and infectious and non-infectious ...
Rachel V. Jimenez, Alexander J. Szalai
doaj +1 more source
Quantitative particle agglutination assay for point-of-care testing using mobile holographic imaging and deep learning [PDF]
Lab on a Chip (2021), 2021 Particle agglutination assays are widely adapted immunological tests that are based on antigen-antibody interactions. Antibody-coated microscopic particles are mixed with a test sample that potentially contains the target antigen, as a result of which the particles form clusters, with a size that is a function of the antigen concentration and the ...
arxiv +1 more source
Role of C-Reactive Protein at Sites of Inflammation and Infection
Frontiers in Immunology, 2018 C-reactive protein (CRP) is an acute inflammatory protein that increases up to 1,000-fold at sites of infection or inflammation. CRP is produced as a homopentameric protein, termed native CRP (nCRP), which can irreversibly dissociate at sites of ...
Nicola R. Sproston, Jason J. Ashworth
doaj +1 more source
Frontiers in Immunology, 2022 C-reactive protein (CRP) has been shown to be a potential candidate target in the immunotherapy of severe influenza A infection. However, it is unclear on the pathogenesis associated with CRP in influenza infections.
Zhuohan Zhang +9 more
doaj +1 more source