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C-reactive protein [PDF]

Radiopaedia.org, 2012
CRP is phylogenetically a highly conserved plasma protein, with homolog in vertebrates and many invertebrates that participates in the systemic response to inflammation.
Moneer Faraj, Nihaya Salem
semanticscholar   +4 more sources

Diagnostic strategies for C-reactive protein [PDF]

BMC Cardiovascular Disorders, 2002
Background Serum C-reactive protein (CRP) has been identified in prospective epidemiological research as an independent risk marker for cardiovascular disease. In this paper, short-term biological variation of CRP is documented and a strategy to test the
Kluft Cees, Meijer Piet, Vrijkotte Tanja GM, Riese Harriëtte, de Geus Eco JC   +4 more
doaj   +5 more sources

C-Reactive Protein and Arteriosclerosis

Mediators of Inflammation, 2014
Although extensively studied and indeed emotionally discussed for more than two decades the role of C-reactive protein (CRP) in cardiovascular disease remains controversial. Three major questions are still not yet resolved. (1) Is CRP a clinically relevant marker of cardiovascular risk? (2) Is CRP even more than a risk marker, that is, a risk factor in
Jan Torzewski, Jianglin Fan, Heribert Schunkert, Alexander Szalai, Michael Torzewski   +4 more
doaj   +4 more sources

Functionality of C-Reactive Protein for Atheroprotection [PDF]

Frontiers in Immunology, 2019
C-reactive protein (CRP) is a pentameric molecule made up of identical monomers. CRP can be seen in three different forms: native pentameric CRP (native CRP), non-native pentameric CRP (non-native CRP), and monomeric CRP (mCRP).
Sanjay K. Singh, Alok Agrawal
doaj   +5 more sources

C-reactive Protein [PDF]

Journal of Biological Chemistry, 2004
C-reactive protein (CRP) is a phylogenetically highly conserved plasma protein, with homologs in vertebrates and many invertebrates, that participates in the systemic response to inflammation. Its plasma concentration increases during inflammatory states, a characteristic that has long been employed for clinical purposes.
David Samols, Irving Kushner, Steven Black   +2 more
openaire   +3 more sources

Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein.

New England Journal of Medicine, 2008
BACKGROUND Increased levels of the inflammatory biomarker high-sensitivity C-reactive protein predict cardiovascular events. Since statins lower levels of high-sensitivity C-reactive protein as well as cholesterol, we hypothesized that people with ...
P. Ridker, E. Danielson, F. Fonseca, J. Genest, A. Gotto, J. Kastelein, W. Koenig, P. Libby, A. Lorenzatti, Jean G Macfadyen, B. Nordestgaard, J. Shepherd, J. Willerson, R. Glynn   +13 more
semanticscholar   +1 more source

C-Reactive Protein as a Biomarker for Major Depressive Disorder?

International Journal of Molecular Sciences, 2022
The etiopathogenesis of depression is not entirely understood. Several studies have investigated the role of inflammation in major depressive disorder. The present work aims to review the literature on the association between C-Reactive Protein (CRP) and
L. Orsolini, S. Pompili, S. Tempia Valenta, V. Salvi, U. Volpe   +4 more
semanticscholar   +1 more source

Deficiency of C-reactive protein or human C-reactive protein transgenic treatment aggravates influenza A infection in mice

Frontiers in Immunology, 2022
C-reactive protein (CRP) has been shown to be a potential candidate target in the immunotherapy of severe influenza A infection. However, it is unclear on the pathogenesis associated with CRP in influenza infections.
Zhuohan Zhang, Zhuohan Zhang, Yongjun Gao, Yongjun Gao, Li Li, Li Li, Junhao Luo, Junhao Luo, Rongbao Gao, Rongbao Gao   +9 more
doaj   +1 more source

C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women.

New England Journal of Medicine, 2000
BACKGROUND Since inflammation is believed to have a role in the pathogenesis of cardiovascular events, measurement of markers of inflammation has been proposed as a method to improve the prediction of the risk of these events.
P. Ridker, C. Hennekens, Julie E. Buring, N. Rifai   +3 more
semanticscholar   +1 more source

The role of C-reactive protein as a prognostic marker in COVID-19

International Journal of Epidemiology, 2021
Background C-reactive protein (CRP) is a non-specific acute phase reactant elevated in infection or inflammation. Higher levels indicate more severe infection and have been used as an indicator of COVID-19 disease severity.
Dominic Stringer, P. Braude, P. Myint, L. Evans, J. Collins, A. Verduri, T. Quinn, A. Vilches-Moraga, M. Stechman, L. Pearce, S. Moug, K. McCarthy, J. Hewitt, B. Carter, Eilidh Alice Aine Carly Ross Giovanni Caroline Joanna Tar Bruce Einarsson McGovern Bisset Alexander Guaraldi, E. Bruce, A. Einarsson, Ā. McGovern, C. Bisset, R. Alexander, G. Guaraldi, C. Murphy, J. Kelly, Tarik El Jichi Mutasem, Sandeep Singh, D. Paxton, W. Harris, J. Hesford, M. Holloway, E. Mitchel, F. Rickard, N. Galbraith, E. Bhatti, J. Edwards, S. Duffy, F. Barlow-Pay, Madeline Garcia, S. Sangani, T. Kneen, Thomas Lee, A. Price, C. Davey, Sheila Jones, K. Lunstone, A. Cavenagh, C. Silver, T. Telford, R. Simmons   +47 more
semanticscholar   +1 more source