Results 41 to 50 of about 2,732,208 (333)
C-Reactive Protein and Cancer—Diagnostic and Therapeutic Insights
Frontiers in Immunology, 2020 Cancer disease describes any pathology involving uncontrolled cell growth. As cells duplicate, they can remain localized in defined tissues, forming tumor masses and altering their microenvironmental niche, or they can disseminate throughout the body in ...
Peter C. Hart +3 more
semanticscholar +1 more source
BMC Medical Genetics, 2009 Background Elevated baseline C-reactive protein (CRP) levels are associated with increased risk for developing cardiovascular disease. Several CRP gene variants have been associated with altered baseline CRP levels in ambulatory populations. However, the
Collard Charles D +6 more
doaj +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Prognostic value of C-reactive protein in patients with COVID-19
medRxiv, 2020 Background Elevated serum C-reactive protein (CRP) level was observed in most patients with COVID-19. Methods Data of COVID-19 patients with clinical outcome in a designated hospital in Wuhan, China, were retrospectively collected and analyzed from Jan ...
Xiaoming Luo +11 more
semanticscholar +1 more source
International Journal of Medical Biochemistry, 2022 INTRODUCTION: Coronavirus disease 2019 (COVID-19), a global pandemic with catastrophic consequences for healthcare systems causing serious respiratory illness, was first reported in China.
Çiğdem Damla Deniz +6 more
doaj +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
C-reactive protein as an early predictor of COVID-19 severity
Journal of Medical Biochemistry, 2020 Background Data for predicting severity of patients with COVID-19 infection are sparse and still under investigation. We retrospectively studied whether the admission serum C-reactive protein level (CRP) can serve as nearly predictor of disease severity ...
Maryame Ahnach +4 more
semanticscholar +1 more source
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Antibodies to C reactive protein [PDF]
Annals of the Rheumatic Diseases, 2006 C reactive protein (CRP) is a known indicator of inflammation. Serum CRP is often raised in patients with inflammatory conditions.To determine whether individuals make antibodies to CRP and whether this might affect serum CRP concentrations.An enzyme linked immunosorbent assay was developed for the detection of antibodies to CRP.
Peter H. Schur, Barbara J Rosenau
openaire +3 more sources
Development of canine C-reactive protein assays
Acta Veterinaria Scandinavica, 2020 C-reactive protein (CRP), which is released during tissue damage and inflammation, is a useful nonspecific inflammatory marker in both human and veterinary clinical practice.
Takaki Waritani +2 more
doaj +1 more source