Results 51 to 60 of about 2,732,208 (333)

Social context prevents heat hormetic effects against mutagens during fish development

FEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere, Claudio Silva De Freitas, Adam Bates, Kenneth B. Storey, Pedro Beltran‐Alvarez, Katharina C. Wollenberg Valero   +5 more
wiley   +1 more source

C-reactive protein levels and outcomes after statin therapy.

New England Journal of Medicine, 2005
BACKGROUND Statins lower the levels of low-density lipoprotein (LDL) cholesterol and C-reactive protein (CRP). Whether this latter property affects clinical outcomes is unknown.
P. Ridker, C. Cannon, D. Morrow, N. Rifai, L. Rose, C. Mccabe, M. Pfeffer, E. Braunwald   +7 more
semanticscholar   +1 more source

Correlation of C-reactive protein with clinical outcome in critically ill patients with sepsis

Journal of Medical and Scientific Research
Introduction: Biomarkers like C-reactive protein (CRP) identify patients with sepsis and are helpful in predicting the severity of sepsis. The objective of the study was to correlate CRP with mortality in patients with sepsis admitted to intensive care ...
Kumar C, Talwar V, Kumar P, Chhabra PH
doaj   +1 more source

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

FEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke, Izadora Volpato Rossi, Marcel I. Ramirez   +2 more
wiley   +1 more source

Gall bladder wall thickness and C-reactive protein as a predictor of difficult laparoscopic cholecystectomy

Journal of Medical and Scientific Research
ver the past two decades, laparoscopic cholecystectomy has become the preferred method for treating gallstone disease. Despite its many benefits, it is not without potential complications.
Nair A, Appukuttan A, Mathew J, Oommen AN, Joseph A   +4 more
doaj   +1 more source

Agar-Gel Precipitin-Inhibition Technique for C-Reactive Protein Determinations [PDF]

, 1965
John G. Ray, Donald E. Shay
  +5 more sources

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

FEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source

Autophagy in cancer and protein conformational disorders

FEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

FEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp, Katharina Rataj, Stefanie König, Marcia E. Newcomer, Oliver Werz, Ulrike Garscha   +5 more
wiley   +1 more source

From C-Reactive Protein to Interleukin-6 to Interleukin-1: Moving Upstream To Identify Novel Targets for Atheroprotection.

Circulation Research, 2016
Plasma levels of the inflammatory biomarker high-sensitivity C-reactive protein (hsCRP) predict vascular risk with an effect estimate as large as that of total or high-density lipoprotein cholesterol.
P. Ridker
semanticscholar   +1 more source