Results 151 to 160 of about 69,600 (248)

<i>Orientia tsutsugamushi</i> binds to multiple C-type lectin receptors. [PDF]

open access: yesInfect Immun
Hefter V   +5 more
europepmc   +1 more source

Immunoregulatory Property of C-Type Lectin-Like Receptors in Fibrosing Interstitial Lung Diseases

open access: yesImmunoregulatory Property of C-Type Lectin-Like Receptors in Fibrosing Interstitial Lung Diseases
The innate immune system identifies exogenous threats or endogenous stress through germline-encoded receptors called pattern recognition receptors (PRRs) that initiate consecutive downstream signaling pathways to control immune responses. However, the contribution of the immune system and inflammation to fibrosing interstitial lung diseases (ILD ...
openaire  

Degradomics for large‐scale mechanistic insights on proteases and proteolysis in human health

open access: yesThe FEBS Journal, EarlyView.
Proteolysis has an important role in human disease but remains relatively unexplored. Degradomics, the uncovering of proteolysis in tissues, cells, and proteins, uses mass spectrometry‐based terminomics to identify protein termini occurring therein (forward degradomics) and to define the actions of proteases (reverse degradomics).
Daniel R. Martin   +2 more
wiley   +1 more source

Latent Neoehrlichia mikurensis Infections May Be Reactivated in Patients With B‐Cell Lymphomas Treated With Rituximab

open access: yesImmunology, EarlyView.
Eight percent of this cohort of patients had a latent Neoehrlichia mikurensis infection. It was only the latently infected patients who had N. mikurensis‐specific T cells, not the matched B‐cell lymphoma patients without the infection. The T‐cell responses of latently infected patients included perforin‐expressing Th1 and CD8+ T cells that upregulated ...
Linda Wass   +4 more
wiley   +1 more source

Blood Immunopathology of Tuberculosis Patients Disrupts Monocyte‐Dependent T‐Cell Activation and Cytokine Expression

open access: yesImmunology, EarlyView.
TB serum selectively disrupts monocyte‐dependent PHA T cell activation and cytokines associated with proliferation while preserving SEB T cell and Pam3/PHA monocyte cytokine responses. ABSTRACT Pulmonary tuberculosis in humans is characterised by features of immunopathology, which influence both antimycobacterial therapy and the long‐term prognosis. In
Joseph F. Arthur   +20 more
wiley   +1 more source

Bacterial cell envelope components of gut commensals: effects in host-microbe interaction. [PDF]

open access: yesAnn Med
Vilela Rodrigues T   +6 more
europepmc   +1 more source

The receptor‐like pseudokinase LENG stimulates chilling tolerance in rice by inhibiting the activity of the OsCRPK1‐OsGF14d module

open access: yesJournal of Integrative Plant Biology, EarlyView.
The rice receptor‐like pseudokinase LENG enhances chilling tolerance by binding to and suppressing the kinase activity of OsCRPK1, thereby preventing OsCRPK1‐mediated phosphorylation of the cold‐tolerance positive regulator OsGF14d. ABSTRACT Cold damage during the seedling and reproductive stages has a pronounced impact on rice development and yield ...
Shuting Yuan   +12 more
wiley   +1 more source

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