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C-Type Lectin-Like Receptor 2 (CLEC-2)
2016C-type lectin-like receptor 2 (CLEC-2) has been identified as a receptor for a platelet-activating snake venom, rhodocytin. CLEC-2 elicits powerful platelet activation signals in a manner dependent on Src, Syk kinases, and phospholipase Cγ2, similar to the collagen receptor glycoprotein (GP) VI/FcRγ-chain complex.
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Acta Neurologica Scandinavica, 2019
Increased permeability and changes in gut microbiota contributed to the pathogenesis of Alzheimer's disease (AD). Zonulin is a key modulator that regulates intestinal barrier function. Peripheral platelet alterations have been involved in AD pathology. C-type lectin-like receptor 2 (CLEC-2) is a receptor on the platelet surface for activation.
Xin Wang +4 more
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Increased permeability and changes in gut microbiota contributed to the pathogenesis of Alzheimer's disease (AD). Zonulin is a key modulator that regulates intestinal barrier function. Peripheral platelet alterations have been involved in AD pathology. C-type lectin-like receptor 2 (CLEC-2) is a receptor on the platelet surface for activation.
Xin Wang +4 more
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C-type lectin-like receptor 2 in lung epithelium protects against acute lung injury
American Journal of Respiratory Cell and Molecular BiologyAbstract C-type lectin-like receptor 2 (CLEC2) is a transmembrane receptor highly expressed on platelets, which regulates platelet aggregation and immune response. Yet, the function of CLEC2 in lung epithelium and its contribution to acute lung injury (ALI) is unclear.
Tian Jiang +12 more
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The characterization of a novel C-type lectin-like receptor, CLEC9A
2008Includes abstract. Includes bibliographical references (leaves 147-161).
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Molecular organization and function of C-type lectin like receptors on dendritic cells
2003Item does not contain ...
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Platelet c-type lectin-like receptor reduces cholestatic liver injury in mice
Journal of Hepatology, 2018S. Maruyama +3 more
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