Results 261 to 270 of about 243,058 (345)

Endocrine Resistance Score Based on Three Key Genes Predicts Prognosis and Reveals Potential Therapeutic Targets for ER+HER2− Breast Cancer

Cell Proliferation, EarlyView.
We generated endocrine‐resistant BC cell lines and identified CLEC3A, PCDH10, and ST3GAL1 as key endocrine‐resistant genes. More importantly, we validated their role in mediating resistance through PI3K‐AKT signalling and developed a predictive ERS with strong clinical relevance.
Liqin Ping, Lewei Zhu, Nian Chen, Xikun Liu, Jirui Zhong, Xiaoqing Sun, Hailin Tang, Kaiming Zhang   +7 more
wiley   +1 more source

Macrophage inducible C-type lectin (Mincle) recognizes glycosylated surface (S)-layer of the periodontal pathogen Tannerella forsythia

, 2017
Sreedevi Chinthamani, Rajendra P. Settem, Kiyonobu Honma, Jason G. Kay, Ashu Sharma   +4 more
openalex   +2 more sources

Adhesion of Immunoglobulins to Band3 Promotes Increased Erythrocyte Sedimentation Rate in Multiple Myeloma

Cell Proliferation, EarlyView.
Decreased sialic acid increases the adhesion of RBC membranes to immunoglobulins leading to an increased erythrocyte sedimentation rate (ESR). The increase in reactive oxygen species (ROS) damages the sialic acid glycosyl chains on the surface of RBC membrane proteins, causing the membrane proteins to be overexposed to the plasma environment due to the
Sicheng Bian, Jiangxia Cui, Xialin Zhang, Chongzhi Bai, Yanhong Tan, Zhuanghui Hao, Xingpeng Bu, Changxin Qu, Lili Sun, Leilei Lin, Qi Wang, Zhengrui Li, Xufeng Huang, Hengrui Liu, Ruo Wang, Yinghua Li, Hongwei Wang   +16 more
wiley   +1 more source

Localization and characterization of C-type lectin-like family of proteins in Leptospira interrogans

, 2007
Amanda Lee Toot
openalex   +2 more sources

Use of the oral microbiota as screening test to identify children at risk for caries development. A systematic review of longitudinal studies

European Journal of Oral Sciences, EarlyView.
Abstract This study investigated trends in oral microbiota composition (index test) that could indicate potential candidates to identify children at risk for dental caries development compared with visual/tactile examination (reference test). MEDLINE/PubMed, Web of Science, Embase, Scopus, Lilacs, SciELO, and Google Scholar databases were searched up ...
Heitor Sales de Barros Santos, Maria Eduarda Lisboa Pagnussatti, Marisa Maltz, Rodrigo Alex Arthur   +3 more
wiley   +1 more source

A novel malnutrition assessment model predicts the inflammatory storm of relapsed/refractory acute myeloid leukemia following C-type lectin-like molecule-1 chimeric antigen receptor T therapy. [PDF]

Front Nutr
Zhang T, Li M, Zhang X, Zhao M, Jiang Y, Wang X, Zhao Y, Shi X, Qu W, Zhang Y, Bai X, Wang B, Zhao M.   +12 more
europepmc   +1 more source

Evolutionary divergence and functional insights into the heteromeric cis‐prenyltransferase of Paramecium tetraurelia

The FEBS Journal, EarlyView.
Heteromeric cis‐prenyltransferases (CPT) are indispensable for dolichol synthesis and protein N‐glycosylation in most eukaryotes. The catalytic subunits are strongly conserved throughout evolution, in contrast to the evolutionarily variable accessory subunits. The POC1 protein from Paramecium tetraurelia is the smallest identified CPT‐accessory subunit
Agnieszka Onysk, Kamil Steczkiewicz, Mariusz Radkiewicz, Paweł Link‐Lenczowski, Przemysław Surowiecki, Karolina Sztompka, Kariona A. Grabińska, Jacek K. Nowak, Liliana Surmacz   +8 more
wiley   +1 more source

Biochemical analysis of Caenorhabditis elegans surface mutants [PDF]

, 1997
Blaxter, M.L., Link, C., Silverman, M.
core  

Structural and functional characterization of the newly identified Photorhabdus laumondii tumor necrosis factor‐like lectin

The FEBS Journal, EarlyView.
We characterize the PLTL lectin from Photorhabdus laumondii, which adopts a unique TNF‐like fold. Binding assays reveal a preference for branched histo‐blood group oligosaccharides. Protein crystallography uncovers a novel hexameric assembly and identifies key residues involved in carbohydrate recognition.
Filip Melicher, Pavel Dobeš, Jan Komárek, Lukáš Faltinek, Marek Korsák, Petra Sýkorová, Josef Houser, Michaela Wimmerová   +7 more
wiley   +1 more source

A c-type lectin <i>HcLec1</i> with dual function of immunology and mineralization from the freshwater oyster (<i>Hyriopsis cumingii</i> Lea). [PDF]

Front Immunol
Chen X, Shen X, Liu S, Li W, Wang H, Li J, Bai Z.   +6 more
europepmc   +1 more source