A newly identified three-domain C-type lectin associated with blood feeding in the tick Ixodes ricinus [PDF]
Kateryna Kotsarenko +10 more
openalex +1 more source
A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer
Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou +4 more
wiley +1 more source
Anti-allodynic effect of intrathecal antibodies against macrophage-inducible C-type lectin in spinal nerve ligation model in rat. [PDF]
Kang DH +4 more
europepmc +1 more source
Properties and N-Terminal amino acid sequences of three Erythrina lectins from Costa Rica (Leguminosae) [PDF]
Aragón-Ortiz, Federico +2 more
core
Behind the scenes: how the EMILIN/Multimerin family shapes the cancer landscape
The EMILIN/Multimerin family members regulate key hallmarks of cancer—including apoptosis, angiogenesis, metastasis, and tumor microenvironment remodeling. As indicated, their function in immune evasion, drug resistance, and metabolic reprogramming remains largely unexplored.
Evelina Poletto +9 more
wiley +1 more source
Identification and functional analysis of C-type lectin from mosquito Aedes albopictus in response to dengue virus infection. [PDF]
Gao S +11 more
europepmc +1 more source
Multimeric IgM‐fragment crystallizable region (Fc) fragments retain the ability to bind C1q and initiate the classical complement pathway, leading to C4 activation and deposition in vitro. However, the Fc cores can also inhibit complement‐dependent cytotoxicity by competing with surface‐bound antibodies for C1q engagement.
Andrea J. Pinto +9 more
wiley +1 more source
Detection of Thrombosis Using Soluble C-Type Lectin-like Receptor-2 with D-Dimer Level and Platelet Count. [PDF]
Wada H +8 more
europepmc +1 more source
The authors investigated the effects of various glycan ligands for CLEC10A, a lectin receptor expressed on dendritic cells (DCs). Monocyte‐derived DCs were stimulated with glycan‐conjugated dendrimers in combination with the TLR1/2 ligand Pam3CysK4, and responses were investigated at the mRNA and protein level.
Nadia L. van der Meijs +7 more
wiley +1 more source
Legionella pneumophila modulates macrophage functions through epigenetic reprogramming via the C-type lectin receptor Mincle. [PDF]
Stegmann F, Diersing C, Lepenies B.
europepmc +1 more source

