Results 281 to 290 of about 237,325 (347)

Genome‐Wide Blood DNA Methylation Profiling in Birch Pollen Allergic Patients Undergoing Allergen‐Specific Immunotherapy

open access: yesAllergy, EarlyView.
Whole genome‐wide DNA methylation analysis of whole blood of patients undergoing 6 months of birch pollen subcutaneous allergen immunotherapy revealed epigenetic changes linked to allergen immunotherapy. Birch pollen AIT decreases methylation in HLA genes and induces methylation in genes associated with Th2 and TGF‐β pathways, increases CD8+ T cell ...
Angelika Lahnsteiner   +8 more
wiley   +1 more source

The use of deidentified organ donor testes for research

open access: yesAndrology, EarlyView.
Abstract Our knowledge of testis development and function mainly comes from research using mammalian model organisms, primarily the mouse. However, there are integral differences between men and other mammalian species regarding cellular composition and expression profiles during fetal and post‐natal testis development and in the mature testis ...
Marina V. Pryzhkova   +4 more
wiley   +1 more source

Lactate inhibits glucose‐induced zigzag motility and enhances linear motility in bull spermatozoa by suppressing glycolysis

open access: yesAndrology, EarlyView.
Abstract Background Energy metabolism and substrate balance are critical determinants of sperm motility and fertility. Linear motility is necessary for sperm forward movement, whereas hyperactivated motility is a prerequisite for fertilization. The preference of metabolic pathways depends on substrate availability which controls sperm motility. However,
Md Faizul Hossain Miraz   +4 more
wiley   +1 more source

The physiological and pathological effects of sphingolipid metabolism and signaling in the central nervous system

open access: yesBrain Pathology, EarlyView.
Sphingolipids are vital components of cell membranes. Metabolic disruptions of sphingolipids, including ceramide and sphingosine‐1‐phosphate, are linked to neurological disorders. This article summarizes the classification, structure, and metabolic processes of sphingolipids, and the physiological and pathological effects of sphingolipid metabolism and
Tian Li   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy