Results 121 to 130 of about 149 (148)

C-type natriuretic peptide and heart failure

Pharmacological Research, 2006
C-type natriuretic peptide (CNP) is a peptide produced by the vascular endothelium with vasodilative properties. It shares structural and physiological properties with the atrial and brain natriuretic peptides (ANP and BNP), whose central role in the pathophysiology of heart failure (CHF) is firmly established.
Del Ry S, Passino C, Emdin M, Giannessi D   +3 more
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C‐type natriuretic peptide in prostate cancer

APMIS, 2009
C‐type natriuretic peptide (CNP) is expressed in the male reproductive organs in pigs. To examine whether the human prostate also expresses the CNP gene, we measured CNP and N‐terminal proCNP in prostate cancer tissue extracts and performed immunohistochemical biopsy staining.
Nielsen, Soeren Junge, Iversen, Peter, Rehfeld, Jens F., Jensen, Helle Lone, Goetze, Jens Peter   +4 more
openaire   +4 more sources

C-type natriuretic peptide: a selective cardiovascular peptide

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 1993
Studies were performed in three groups of anesthetized dogs to compare the structurally related peptides atrial natriuretic peptide (ANP) and C-type natriuretic peptide (CNP). Group 1 (n = 5) and group 2 (n = 4) received intravenous infusions of CNP or ANP respectively at doses of 10 ng.kg-1.min-1 and 100 ng.kg-1.min-1.
Denise M. Heublein, Chi-Ming Wei, John C. Burnett, Alfredo L. Clavell, A. J. Stingo   +4 more
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C-Type Natriuretic Peptide and Overgrowth

2009
Natriuretic peptides are a family of structurally related peptides with different distinct biological effects. C-type natriuretic peptide (CNP)-mediated signaling is important for endochondral ossification and intervenes in the control of chondrocyte maturation by regulating the balance between proliferation and terminal differentiation. CNP is encoded
BOCCIARDI, RENATA, RAVAZZOLO, ROBERTO
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Plasma brain natriuretic peptide and C-type natriuretic peptide in essential hypertension

Journal of Hypertension, 1994
To study the relationship between hypertension and the plasma levels of brain natriuretic peptide (BNP) and C-type natriuretic peptide (CNP), and to determine whether the plasma levels of BNP and CNP are correlated.A cross-sectional study of the plasma levels of BNP and CNP in hypertensive patients and normotensive controls matched for age and sex was ...
Brown, MJ, Cheung, BM
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C-type natriuretic peptide and atrial natriuretic peptide receptors of rat brain

American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 1993
Natriuretic peptide receptors in rat brain were mapped by in vitro autoradiography using 125I-labeled [Tyr0]CNP-(1-22) to bind atrial natriuretic peptide receptor (ANPR)-B and ANPR-C receptors selectively, and 125I-labeled alpha-ANP to select ANPR-A and ANPR-C receptors.
Zhiyi Zuo, John Brown
openaire   +3 more sources

N-terminal pro-C-type natriuretic peptide, but not C-type natriuretic peptide, is greatly elevated in the fetal circulation

Clinical Science, 2004
We have identified recently a new peptide, NT-proCNP(1–50) (N-terminal pro-C-type natriuretic peptide), in the circulation of humans and sheep. A previous report of an elevated fetal–maternal gradient in immunoreactive CNP raised the possibility that processing and metabolism of proCNP may differ in maternal and fetal tissues.
Eric A. Espiner, Risto Kaaja, Timothy C. R. Prickett, M. Gary Nicholls, Timothy G. Yandle, A. Mark Richards   +5 more
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Receptor selectivity of natriuretic peptide family, atrial natriuretic peptide, brain natriuretic peptide, and C-type natriuretic peptide.

Endocrinology, 1992
To elucidate the ligand-receptor relationship of the natriuretic peptide system, which comprises at least three endogenous ligands, atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP), and C-type natriuretic peptide (CNP), and three receptors, the ANP-A receptor or guanylate cyclase-A (GC-A), the ANP-B receptor or guanylate cyclase-B (GC ...
Hiroshi Arai, Kazuwa Nakao, Masashi Mukoyama, Shin Ichi Suga, Gotaro Shirakami, Yoshikazu Kambayashi, Yoshihiro Ogawa, Yoshihiko Saito, Kiminori Hosoda, Ken Inouye   +9 more
openaire   +2 more sources

C-type natriuretic peptide (CNP) is the major natriuretic peptide in human cerebrospinal fluid

Brain Research, 1993
In order to investigate whether C-type natriuretic peptide (CNP) is present in human cerebrospinal fluid (CSF), we measured CNP-like immunoreactivity (-LI) in human CSF by specific radioimmunoassay (RIA) for CNP. We also measured atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) concentrations in human CSF. ANP-LI, BNP-LI, and CNP-LI
Izumi Nagata, Norio Hama, Osamu Hirai, Shin Ichi Suga, Osamu Nakagawa, Susumu Miyamoto, Takaaki Kaneko, Hiroo Imura, Gotaro Shirakami, Hiroaki Kubo, Haruhiko Kikuchi, Kazuwa Nakao   +11 more
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Selective Activation of the B Natriuretic Peptide Receptor by C-Type Natriuretic Peptide (CNP)

Science, 1991
The natriuretic peptides are hormones that can stimulate natriuretic, diuretic, and vasorelaxant activity in vivo, presumably through the activation of two known cell surface receptor guanylyl cyclases (ANPR-A and ANPR-B). Although atrial natriuretic peptide (ANP) and, to a lesser extent, brain natriuretic peptide (BNP) are efficient activators of the ...
Kenji Kangawa, Gregory L. Bennett, Kerry J. Koller, Naoto Minamino, Hisayuki Matsuo, David V. Goeddel, David G. Lowe   +6 more
openaire   +3 more sources