Results 181 to 190 of about 55,167 (238)

Phthalate Metabolite, Mono(2‐Ethyl‐5‐Hydroxyhexyl) Phthalate (MEHHP), Promotes Uterine‐Fibroid–Associated Phenotypes in Myometrial Stem Cell‐Derived 3D Organoids

Environmental Toxicology, EarlyView.
ABSTRACT This study investigates how phthalate exposure contributes to uterine fibroid (UF) development by studying the effects of the Mono‐(2‐ethyl‐5‐hydroxyhexyl) phthalate (MEHHP), a metabolite of Di(2‐ethylhexyl) phthalate, on myometrial stem cells (MMSCs).
Somayeh Vafaei, Mervat M. Omran, Qiwei Yang, Sandra Madueke‐Laveaux, Ami R. Zota, Ayman Al‐Hendy, Mohamed Ali   +6 more
wiley   +1 more source

Germinal Center-Like Tertiary Lymphoid Structures Mark Immune Responsiveness and Enable Checkpoint Immunotherapy in Bladder Cancer. [PDF]

Oncol Res
Yin Z, Zhen X, Li H, Duan H, Hu X, Yu T, Shi Q, Liu Z, Li Y, Zhang P, Dai P, Zhao M, Wang Z, Li C, Wang D, Tong Z.   +15 more
europepmc   +1 more source

Impact of general anaesthesia on immune response to first rabies vaccination in seronegative domestic cats

Veterinary Record, EarlyView.
Abstract Background Despite common concerns, evidence that anaesthesia impairs vaccine efficacy remains limited. This study assessed the impact of general anaesthesia on the immune response to rabies vaccination in cats. Methods Thirty‐five healthy female cats (6–12 months old) undergoing elective spaying were enrolled.
Pierre Bessière, Romane Breysse, Marion Chrétien, Brandon Hayes, Séverine Boullier, Anouck Labadie, Jonathan Rieder, Marine Wasniewski, Géraldine Jourdan   +8 more
wiley   +1 more source

Sex-biased plasma inflammatory protein profile in obesity. [PDF]

Sci Rep
Halland H, Vitorino R, Gerdts E, Midtbø H, Meyer K, Kararigas G.   +5 more
europepmc   +1 more source

Biomarkers to predict outcomes in diabetic foot ulcers

VIEW, EarlyView.
Studies attempting to predict the healing outcome of diabetic foot ulcers (DFUs) have investigated various biological materials and recovered molecules that may aid in discriminating wounds that will heal and those that will not heal. This graphical abstract captures the commonly studied classes of biomarkers in the context of DFUs.
Julie Okiro, Kellie Fortune, Eimear Daly, Luca McCann, Merhan Soltan, Seamus Sreenan, Fabio Quondamatteo   +6 more
wiley   +1 more source

The effect of cladribine tablets on intrathecal inflammation in relapsing-remitting multiple sclerosis. [PDF]

J Neuroinflammation
Marastoni D, Eccher C, Signori A, Anni D, Foschi M, Crescenzo F, Mazziotti V, Virla F, Sicchieri M, Turano E, Tamanti A, Camera V, Ziccardi S, Zanetti G, Pizzini FB, Martini S, Fratucello A, Bonetti B, Sormani MP, Calabrese M.   +19 more
europepmc   +1 more source

Nanobodies as next‐generation targeting platforms: From discovery technologies to translational biomedicine

VIEW, EarlyView.
Nanobodies, derived from the variable domains of camelid heavy‐chain‐only antibodies, have emerged as transformative biomedical tools due to their nanoscale size, exceptional stability, and unique capacity to recognize cryptic epitopes. This review provides a comprehensive overview of the field, outlining the structural and biochemical features of ...
Zhenrui Ye, Xianyang Li, Meixiao Zhan
wiley   +1 more source

Chemokine-chemokine receptor axis: Emerging immunotherapeutic paradigms for solid tumor microenvironment reprogramming. [PDF]

Chin Med J (Engl)
Zhao Y, Wang X, Lei T, Lu H, Zhao Y, Wang G.   +5 more
europepmc   +1 more source

Four‐dimensional immuno‐mechanobiomaterials: Dynamic material cues that program host response to prevent fibrosis and enable regeneration

VIEW, EarlyView.
Dynamic immuno‐mechanobiomaterials with time‐programmed mechanical adaptation orchestrate host responses through precise mechanotransduction and immune‐stromal regulation. These adaptive biomaterials minimize mechanical mismatch, attenuate the forign dy response and fibrosis, promote angiogenesis and controlled extracellular matrix remodeling, and ...
Gobinath Vellapalayam Manoharan, Kathirvel Ayyaswamy, Parthasarathy Vellaichamy, Nagarajan Deivanayagam Pillai, Rithik Gobinath   +4 more
wiley   +1 more source

Single-cell and spatial transcriptomics reveal that the CXCL12-CXCR4 axis drives the immune-desert phenotype in small cell lung cancer by recruiting immunosuppressive CXCR4⁺ neutrophils and S100A8⁺ monocytes. [PDF]

J Immunother Cancer
Zeng P, Li HF, Shu WB, Zhang J, Zhao TC, Hu JW, Wang JF, Wang C, Lu QY, Yang JH, An YL, Chen R.   +11 more
europepmc   +1 more source