Results 171 to 180 of about 18,984,511 (231)

Using Synthetic Glycans to Investigate Anti‐Glycan Antibodies and Explore Their Medical Potential

Angewandte Chemie International Edition, Volume 65, Issue 39, 21 September 2026.
Anti‐glycan antibodies are essential in health and disease. Access to novel glycan structures paves the way for progress in antibody profiling for biomarker discovery, antibody development, and vaccine design. We summarize the strategies to synthesize and utilize synthetic glycans for the development and application of anti‐glycan antibodies in basic ...
Fabienne Weber, Aina Valenti, Jiří Ledvinka, Oren Moscovitz, Peter H. Seeberger   +4 more
wiley   +1 more source

Bile Acid Metabolism as a Unifying Readout for Diet, Microbiome Function, and Gastrointestinal Disease

The FASEB Journal, Volume 40, Issue 17, 15 September 2026.
Dietary components shape the gut microbiome, which modifies bile acids through transformations. The resulting bile acid pool is sensed by host receptors to regulate immunity, metabolism, and intestinal function. Targeted bile acid measurements provide a unifying readout to study diet‐microbiome interactions and to develop next‐generation dietary ...
Jason Dichter
wiley   +1 more source

Proline Stickland fermentation supports <i>C. difficile</i> spore maturation. [PDF]

Appl Environ Microbiol
Carter ZA, O'Brien CE, McBride SM.
europepmc   +1 more source

Synthesis of Glycopeptide Antibiotic Peptide Substrates Using Knorr‐Pyrazole Chemistry

ChemMedChem, Volume 21, Issue 17, 14 September 2026.
The glycopeptide antibiotics (GPAs) are important clinical antibiotics. While chemoenzymatic synthesis of more hydrophilic GPAs like vancomycin has aided our understanding of GPA crosslinking, hydrophobic GPAs remain underexplored. Here, we show that modified Knorr‐pyrazole chemistry improves access to hydrophobic peptidyl‐CoAs, with such substrates ...
Jemma Gullick, W. Ramani H. Weerasinghe, Ralf B. Schittenhelm, Julien Tailhades, Max J. Cryle   +4 more
wiley   +1 more source

Fecal Microbiota-Based Therapies Compared to Fecal Microbiota Transplantation for Preventing Recurrent C difficile Infection. [PDF]

Clin Gastroenterol Hepatol
Nguyen L, Feuerstadt P, Allegretti JR, Axelrad J.   +3 more
europepmc   +1 more source

<i>Clostridioides difficile</i> clinical diagnostic test methods and results are associated with recovery of <i>C. difficile</i> by stool culture. [PDF]

Microbiol Spectr
Skinner AM, Guh AY, Petrella LA, Sambol S, Cheknis A, Johnson S, Czaja CA, Johnston H, Basiliere E, Dhonau RA, Korhonen L, Paulick AL, Samore MH, Adamczyk M, Gargis AS, Gerding DN.   +15 more
europepmc   +1 more source

Infant Acid-Suppressant Medication, C. difficile Colonisation, and Childhood Body Mass Index in a Canadian Cohort. [PDF]

Acta Paediatr
Bridgman SL, Drall KM, Lau AA, Tun HM, Morales-Lizcano NP, Huynh HQ, Mandhane PJ, Moraes TJ, Simons E, Turvey SE, Subbarao P, Scott JA, Kozyrskyj AL.   +12 more
europepmc   +1 more source